Short course · WHO maternal and newborn health

Safe pregnancy and birth: antenatal and postnatal contacts

Most deaths of mothers and newborns can be prevented with good care before, during and after birth, and much of that care can be given in primary care by nurses, midwives and clinical officers. This course takes you through the WHO antenatal (2016) and postnatal (2022) recommendations, then the three emergencies that kill most often around the birth: bleeding, infection and a baby who does not breathe. Each lesson starts from what to do, which medicines to give and who needs referral now.

8 lessonsabout 230 minutes of reading
4 CPD hoursself-declared learning time
15-question quizpass mark 12
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Course objectives
  • Plan and deliver the WHO eight-contact antenatal model and the four postnatal contacts.
  • Give the antenatal preventive package with correct doses: iron and folic acid, calcium, IPTp, tetanus vaccination and deworming.
  • Recognise hypertension, pre-eclampsia and eclampsia, give magnesium sulfate and refer safely.
  • Diagnose and treat anaemia in pregnancy using WHO haemoglobin cut-offs.
  • Recognise danger signs in mothers and newborns after birth, and offer contraception and nutrition advice after birth.
  • Detect postpartum haemorrhage early and start the WHO first-response bundle.
  • Recognise maternal sepsis, give first treatment and refer.
  • Give essential newborn care at birth and start bag-and-mask ventilation within the first minute when a baby does not breathe.
Lesson 1 of 8 · about 20 minutes

The WHO antenatal model: eight contacts

By the end of this lesson you can
  • Describe the 2016 WHO antenatal contact schedule and why it replaced four visits.
  • List what to ask, examine and test at the first contact.

For many years, WHO advised four "focused" antenatal visits. In 2016 WHO published 49 recommendations on routine antenatal care and replaced the four-visit model with a minimum of eight contacts. The evidence suggested that more contacts lead to fewer perinatal deaths and a better experience for women.

Return at 41 weeks if she has not given birth. WHO ANC recommendations (2016).
TrimesterContacts (weeks of pregnancy)
FirstContact 1: up to 12 weeks
SecondContact 2: 20 weeks; contact 3: 26 weeks
ThirdContacts 4 to 8: 30, 34, 36, 38 and 40 weeks

WHO uses the word contact rather than visit because it means a real connection with a health worker. Contacts can be adapted to local services, including outreach and community health workers. Anything missed at one contact should be done at the next.

The first contact

  • History: last menstrual period, previous pregnancies and births, illnesses, medicines, tobacco, alcohol and other substances.
  • Examination: blood pressure, weight, pallor, fundal height or uterine size, fetal heart when audible.
  • Tests: haemoglobin, HIV and syphilis, urine for asymptomatic bacteriuria (culture, or Gram stain if no culture; not dipstick).
  • One ultrasound scan before 24 weeks, where available, to date the pregnancy and detect twins and anomalies. It can be done at contact 1 or contact 2.
  • Ask about intimate partner violence when assessing conditions it may cause, if you are trained, can see her in private and have somewhere to refer.

Every contact

Ask how she is feeling and about danger signs; measure blood pressure; look for anaemia; check fetal growth and the fetal heart; give and check supplements; give one or two key messages; and update her birth and emergency plan. WHO recommends that each woman carries her own case notes, which improves continuity when she is seen by different workers.

Danger signs to teach every womanVaginal bleeding, convulsions, severe headache with blurred vision, fever and too weak to get out of bed, severe abdominal pain, or fast or difficult breathing: go to the facility immediately, day or night.

Worked case 2: Late booking at 28 weeks

Ms F, 31, has her first contact at 28 weeks because the clinic was closed during the rainy season. She has had no tests. BP 118/72, no danger signs.

What should she have today?
Answer: Everything from the first contact: history, BP, Hb, HIV and syphilis tests, urine for bacteriuria where culture or Gram stain is available, and the preventive package (lesson 2). It is now too late for the dating scan before 24 weeks, so do not delay care for it.
When are her next contacts?
Answer: At 30, 34, 36, 38 and 40 weeks, with a return at 41 weeks if she has not given birth. Missed contacts are not repeated: you simply carry on with the schedule from where she is.
Case: Ms A, first pregnancy, 10 weeks

Ms A, 19, comes because her period is late. A pregnancy test is positive and she is about 10 weeks pregnant. The clinic has a haemoglobinometer, rapid HIV and syphilis tests and no ultrasound. The nearest scan is at the district hospital.

When should her next contacts be?

At 20, 26, 30, 34, 36, 38 and 40 weeks: eight contacts in all including today. She should come back at 41 weeks if she has not given birth, and at once with any danger sign.

What tests should she have today, and what about a scan?

Haemoglobin, HIV and syphilis today, and a urine test for bacteriuria if culture or Gram stain is available. Arrange one ultrasound before 24 weeks, ideally by contact 2 at 20 weeks, at the district hospital.

Key points
  • At least eight antenatal contacts: up to 12 weeks, then 20, 26, 30, 34, 36, 38 and 40 weeks.
  • First contact: history, BP, Hb, HIV and syphilis, urine for bacteriuria, plan one scan before 24 weeks.
  • Woman-held notes and a birth and emergency plan at every contact.
Lesson 2 of 8 · about 25 minutes

The preventive package

By the end of this lesson you can
  • Give iron and folic acid, calcium, IPTp, tetanus vaccination and deworming at the right dose and time.
  • Explain which supplements WHO does not recommend for all women.

Iron and folic acid

WHO recommends daily oral iron 30 to 60 mg (elemental) with folic acid 400 micrograms (0.4 mg) for every pregnant woman, to prevent maternal anaemia, puerperal sepsis, low birth weight and preterm birth. Where 40% or more of pregnant women are anaemic, 60 mg is preferred. Folic acid should start as early as possible, ideally before conception, to prevent neural tube defects.

If daily iron is not tolerated because of side effects, and where fewer than 20% of pregnant women are anaemic, weekly iron 120 mg with folic acid 2.8 mg is an option. This is prevention, not treatment.

Calcium

Where diets are low in calcium, give 1.5 to 2.0 g elemental calcium a day to reduce the risk of pre-eclampsia. WHO suggests splitting it into three doses with meals and taking it several hours apart from iron, because the two interfere with each other.

Malaria in pregnancy

In malaria-endemic areas of Africa, give intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) to all pregnant women, starting as early as possible in the second trimester (from 13 weeks), at scheduled contacts at least one month apart, aiming for at least three doses. Together with an insecticide-treated bed net. Use folic acid 0.4 mg, not 5 mg: high doses may stop SP from working.

Tetanus

  • Never vaccinated, or not known: two doses of a tetanus toxoid-containing vaccine one month apart, the second at least two weeks before birth. A third dose six months later, and two more in later years or pregnancies.
  • One to four doses in the past: one dose in this pregnancy, up to a total of five.

Deworming

Where more than 20% of people have soil-transmitted worm infection, give preventive anthelminthic treatment after the first trimester, as part of the national programme.

Not routinely recommended

WHO does not recommend routine vitamin B6, vitamin C and E, or vitamin D supplements, multiple micronutrients, or high-protein supplements for all pregnant women. Vitamin A is only for areas where deficiency is a severe public health problem. Women with high caffeine intake (over 300 mg a day) should cut down.

Who can give itWHO supports task sharing the distribution of supplements and IPTp to a wide range of cadres, including auxiliary nurses, nurses and midwives. A reliable supply matters more than who hands it out.
Case: Mrs B, 16 weeks, malaria area

Mrs B lives in an area with high malaria transmission and lots of hookworm. She is 16 weeks pregnant, Hb 112 g/L. She had two tetanus doses in her last pregnancy three years ago. The pharmacy has stocked folic acid 5 mg tablets instead of combined iron and folic acid.

What should she receive today?

Daily iron 30 to 60 mg with folic acid 0.4 mg; her first dose of IPTp-SP (she is past 13 weeks); one dose of tetanus toxoid-containing vaccine; deworming (she is past the first trimester, in an endemic area); calcium if diets are low in calcium; a bed net.

What is the problem with the 5 mg folic acid?

High-dose folic acid (5 mg or more) may reduce how well SP works. Folic acid for antenatal use should be 0.4 mg daily. Raise it with the pharmacy and district.

Key points
  • Daily iron 30 to 60 mg plus folic acid 0.4 mg for every pregnant woman.
  • Calcium 1.5 to 2.0 g a day where intake is low, several hours apart from iron.
  • IPTp-SP from 13 weeks, at least a month apart, at least three doses, in endemic Africa.
  • Tetanus vaccination according to previous doses; deworming after the first trimester where worms are common.
Lesson 3 of 8 · about 30 minutes

Hypertension, pre-eclampsia and eclampsia

By the end of this lesson you can
  • Classify hypertension in pregnancy and recognise severe pre-eclampsia.
  • Give the magnesium sulfate loading dose and lower severe BP before referral.

Hypertensive disorders affect about one in ten pregnant women. In Africa and Asia, nearly one in ten maternal deaths is associated with them. Most of these deaths can be avoided with timely care.

Classify

Adapted from WHO MCPC (2017).
FindingsClassification
BP 140/90 or more before 20 weeksChronic hypertension
BP 140 to 159 / 90 to 109 twice, 4 hours apart, after 20 weeks; no proteinuriaGestational hypertension
As above with proteinuria 2+ on dipstickPre-eclampsia
BP 160/110 or more with proteinuria, or any severe feature: severe headache, blurred vision, upper abdominal pain, breathlessness, little urine, clonusSevere pre-eclampsia
Convulsions with raised BPEclampsia

Pre-eclampsia may have no symptoms, and swelling of the feet is not a reliable sign. That is why blood pressure is measured at every contact. Eclamptic fits can happen with only modestly raised BP and in about a quarter of cases they happen after the birth.

Magnesium sulfate

Magnesium sulfate is the best drug to prevent and treat eclamptic fits, and WHO recommends it in preference to other anticonvulsants. WHO says it should be available in all health facilities. The full regimen is a loading dose and 24 hours of maintenance. Where the full regimen cannot be given, give the loading dose and transfer immediately.

  • Loading dose (IM regimen): 4 g of 20% solution IV over 5 minutes, then 10 g of 50% deep IM, 5 g in each buttock, with 1 mL of 2% lidocaine in the syringe.
  • Before each maintenance dose: breathing at least 16 per minute, knee reflexes present, urine at least 30 mL per hour.
  • Antidote: calcium gluconate 1 g (10 mL of 10%) IV slowly.

Blood pressure

Treat BP of 160/110 or more. WHO says the choice of drug should depend on the clinician's experience, cost and availability; hydralazine, methyldopa, labetalol and nifedipine have all been widely used. For non-severe hypertension (140 to 159 / 90 to 109), WHO 2020 says to offer treatment where there is good follow-up, with methyldopa or a beta-blocker. Never use ACE inhibitors or ARBs in pregnancy, and do not give ergometrine to women with high BP.

Prevention

  • Low-dose aspirin 75 mg daily for women at high risk (previous pre-eclampsia, diabetes, chronic hypertension, kidney or autoimmune disease, twins), started before 20 weeks.
  • Calcium where intake is low (lesson 2).
  • Bed rest, salt restriction, vitamins C, D and E, and diuretics do not prevent pre-eclampsia.

Worked case 2: Fits two days after birth

A community health worker brings Mrs G to the health centre on day 2 after a normal birth at home. She had a fit an hour ago. BP 158/104, proteinuria 2+. She is drowsy but breathing normally.

What is the diagnosis?
Answer: Postpartum eclampsia. About a quarter of eclamptic fits happen after birth, and the BP need not be very high.
What do you do?
Answer: ABCDE and recovery position; the magnesium sulfate loading dose; check breathing rate, knee reflexes and urine before any further dose; lower BP if it reaches 160/110; transfer with a health worker and calcium gluconate. Keep the baby with her and breastfeeding if possible.
Case: Mrs C, 34 weeks, headache

Mrs C comes to a health centre with a headache that paracetamol has not helped and blurred vision. BP is 164/112 and 162/110 fifteen minutes later. Urine protein 3+. The district hospital is 2 hours away. The health centre has magnesium sulfate, nifedipine and calcium gluconate.

What is the classification?

Severe pre-eclampsia: BP 160/110 or more with proteinuria and severe symptoms after 20 weeks.

What do you do before she leaves?

Give the magnesium sulfate loading dose (4 g IV over 5 minutes plus 10 g deep IM, 5 g in each buttock), give oral nifedipine to bring BP below 160/110 (repeat after 30 minutes if needed, per protocol), start an IV line, and transfer urgently with a health worker, calcium gluconate and a note of the doses. Never leave her alone.

Key points
  • Measure BP at every contact; 140/90 or more after 20 weeks needs a urine protein check.
  • Severe pre-eclampsia or eclampsia: magnesium sulfate loading dose, lower BP of 160/110 or more, urgent transfer.
  • Aspirin 75 mg from before 20 weeks for high-risk women; calcium where diets are low in calcium.
Lesson 4 of 8 · about 20 minutes

Anaemia in pregnancy

By the end of this lesson you can
  • Diagnose and grade anaemia in pregnancy using WHO cut-offs and clinical signs.
  • Treat anaemia and know when to refer.

Anaemia makes women tired and breathless and lowers their reserve if they bleed at birth. Common causes in low-resource settings include iron deficiency, malaria, hookworm, schistosomiasis, HIV, TB and sickle cell disease.

Diagnose

Measure haemoglobin at the first contact. WHO recommends a full blood count, or an on-site haemoglobinometer where there is no laboratory, rather than the haemoglobin colour scale. At later contacts look for pallor of the palms and conjunctiva, and ask about tiredness and breathlessness.

WHO haemoglobin cut-off guideline (2024).
TrimesterAnaemia if Hb is belowSevere if Hb is below
First and third110 g/L70 g/L
Second105 g/L70 g/L
Severe anaemiaHb below 70 g/L, severe pallor, or any pallor with breathing over 30 a minute, tiring easily or breathlessness at rest is severe anaemia: refer urgently and plan birth in a facility that can transfuse.

Treat

  • Increase elemental iron to 120 mg a day with folic acid 400 micrograms until Hb is 110 g/L or more, then go back to the preventive dose (WHO ANC 2016). PCPNC gives this as one 60 mg tablet twice a day for 3 months.
  • Test and treat malaria in endemic areas; make sure IPTp and a bed net are in place.
  • Deworm after the first trimester where worms are common.
  • Reassess at the next contact (4 to 6 weeks); if anaemia persists, check adherence and refer.

After birth, iron (with or without folic acid) for 6 to 12 weeks reduces anaemia where it is common in pregnancy.

Worked case 2: Breathless at 36 weeks

Mrs H, 36 weeks, Hb 64 g/L, is breathless at rest with breathing 34 per minute and very pale palms. Malaria is common in the area.

How do you classify her?
Answer: Severe anaemia: Hb below 70 g/L with breathlessness at rest.
What is the plan?
Answer: Urgent referral to a facility that can transfuse and manage birth; test and treat for malaria; she should give birth where blood is available because she has little reserve if she bleeds (lesson 6).
Case: Mrs D, 24 weeks, tired

Mrs D is 24 weeks pregnant with her fourth child. She says she is tired all the time. Her palms are pale but she is not breathless at rest; breathing rate 22 per minute. Hb on the haemoglobinometer is 88 g/L. She stopped her iron because it upset her stomach.

How do you classify her anaemia?

Second trimester, Hb 88 g/L: moderate anaemia (70 to 94 g/L). No severe signs, so not severe anaemia.

What is your plan?

Explain why iron matters and discuss side effects; restart iron at 120 mg elemental iron a day (for example 60 mg twice daily) with folic acid 0.4 mg; malaria test and IPTp in an endemic area; deworm if indicated; recheck in 4 to 6 weeks and refer if not improving.

Key points
  • Anaemia: Hb below 110 g/L (below 105 in the second trimester); severe below 70 g/L.
  • Treat with 120 mg elemental iron daily plus folic acid until Hb is normal.
  • Treat malaria and worms; refer severe anaemia and plan birth where blood is available.
Lesson 5 of 8 · about 35 minutes

Postnatal care of mother and baby, contraception and nutrition

By the end of this lesson you can
  • Schedule the four WHO postnatal contacts.
  • Recognise maternal and newborn danger signs and give routine postnatal care.
  • Offer contraception after birth that is safe with breastfeeding, and give nutrition advice.

The days after birth are the most dangerous time for mothers and newborns, but postnatal care is often the most neglected part of maternity care. WHO's 2022 recommendations call for a minimum of four postnatal contacts.

ContactWhen
1In the facility for at least 24 hours after a vaginal birth; after a home birth, as early as possible within 24 hours
2Day 3 (48 to 72 hours)
3Between days 7 and 14
4During week 6

The mother

  • First 24 hours: bleeding, uterine tone, fundal height, temperature and pulse from the first hour; BP soon after birth and again within 6 hours; passed urine within 6 hours.
  • Later: well-being, bleeding, urine and bowels, perineum, breasts, headache, tiredness, BP, and mood.
  • Screen for depression and anxiety with a validated tool, with care available for women who screen positive.
  • Offer full contraceptive information and services.
  • Iron for 6 to 12 weeks where anaemia in pregnancy is common.
Mother: go to the facility immediatelyHeavy bleeding (2 or 3 pads soaked in 20 to 30 minutes, or increasing), convulsions, headache with blurred vision, fast or difficult breathing, fever and too weak to get out of bed, severe abdominal pain, calf pain or swelling, or chest pain.

The baby

Newborn danger signs: referNot feeding well, convulsions, breathing over 60 a minute, severe chest indrawing, no spontaneous movement, temperature over 37.5 °C or under 35.5 °C, jaundice in the first 24 hours or yellow palms and soles at any age.
  • Exclusive breastfeeding until 6 months, with support at every contact.
  • Delay the first bath for at least 24 hours.
  • Clean, dry cord care. Chlorhexidine only where harmful substances are commonly put on the cord.
  • Sleep on the back. Immunise according to the national schedule.

Contraception after birth

WHO recommends offering full contraceptive information and services at postnatal contacts. A pregnancy soon after birth carries more risk for mother and baby: WHO advises waiting at least 24 months after a live birth before trying to become pregnant again. Ovulation can return before the first period, especially if the woman is not fully breastfeeding.

Adapted from the WHO Medical eligibility criteria for contraceptive use, 5th edition (2015). Category 1: no restriction; 2: benefits generally outweigh risks; 3: risks usually outweigh benefits; 4: do not use.
MethodBreastfeeding, under 6 weeks after birthNotes
Copper IUDInsert within 48 hours of birth, or wait until 4 weeks or moreNot between 48 hours and 4 weeks
Progestogen-only pill, implantUsually safe to start (MEC category 2)Category 1 from 6 weeks
Progestogen-only injectable (DMPA)Not usually recommended before 6 weeks (category 3)Category 1 from 6 weeks
Combined pill, patch or ringDo not use (category 4)Breastfeeding: wait until 6 months; not breastfeeding: from 3 to 6 weeks depending on clot risk
Lactational amenorrhoea method (LAM)Works only if all three: no periods, fully or nearly fully breastfeeding, baby under 6 monthsStart another method when any one stops
CondomsAny timeAlso protect against STIs and HIV

Nutrition after birth

  • Encourage a varied diet and enough to drink. Breastfeeding needs extra food; do not let the mother eat less to save food for others.
  • Give iron, with or without folic acid, for 6 to 12 weeks after birth where anaemia in pregnancy is common (WHO 2022).
  • If she had severe anaemia or a large blood loss, check Hb and treat (lesson 4).
  • Keep breastfeeding support at every contact: good attachment, feeding on demand, nothing else to drink for the baby.

You can breastfeed and still use a family planning method that is safe for your baby. Let us choose one today, before your periods come back.

Worked case 2: Contraception at the week-6 contact

Mrs J, 24, is fully breastfeeding her 6-week-old baby and has had no period. She wants to wait at least two years before another pregnancy and does not want an IUD.

What can she use now?
Answer: A progestogen-only method: implant, progestogen-only pill or DMPA are all category 1 from 6 weeks while breastfeeding. LAM also works now, but only while all three conditions hold.
What should she not be given?
Answer: Combined oral contraceptives: not until 6 months after birth while breastfeeding, because they can reduce milk supply.
Case: Home visit on day 3

A community health worker visits Mrs E on day 3 after a home birth. Mrs E feels tired but well, her bleeding is less than on day 1, BP is 132/84. The baby has been sleepy and feeding poorly since this morning and feels hot; the temperature is 38.0 °C.

Who needs urgent referral?

The baby: not feeding well and a temperature above 37.5 °C are both newborn danger signs. Refer urgently to the health facility, with the mother continuing to breastfeed if the baby can.

What should still be done for Mrs E?

Reassure, check for her own danger signs, ask about mood, support breastfeeding, and plan her next contacts (days 7 to 14 and week 6). Remind her of her own danger signs, and discuss contraception.

Key points
  • Four postnatal contacts: first 24 hours, day 3, days 7 to 14, week 6.
  • Check BP after birth and at every contact; BP can peak at the end of the first week.
  • Newborn danger signs: poor feeding, convulsions, fast breathing, chest indrawing, no movement, fever or low temperature, early jaundice.
  • Exclusive breastfeeding, delayed bathing, clean dry cord, depression screening and contraception.
  • Offer contraception at every postnatal contact: copper IUD within 48 hours or from 4 weeks; progestogen-only methods while breastfeeding; no combined pill before 6 months if breastfeeding.
  • Advise at least 24 months before the next pregnancy; iron for 6 to 12 weeks where anaemia is common.
Lesson 6 of 8 · about 35 minutes

Postpartum haemorrhage: prevent, detect early, act at once

By the end of this lesson you can
  • Prevent postpartum haemorrhage with a uterotonic for every woman.
  • Detect PPH early by measuring blood loss and watching vital signs.
  • Start the WHO first-response bundle (MOTIVE) and know when to escalate.

Postpartum haemorrhage (PPH) is the leading direct cause of maternal death worldwide. Most deaths happen within hours of birth, and many happen because bleeding is recognised late: looking at blood loss usually underestimates it. WHO now recommends measuring blood loss objectively, for example with a calibrated drape, and acting early.

When to act (WHO, FIGO and ICM 2025)Measured blood loss of 500 mL or more, or 300 mL or more with any abnormal vital sign (fast pulse, low blood pressure, signs of shock): start the treatment bundle now. Do not wait for the woman to look unwell.

Prevent: every woman, every birth

  • Give a uterotonic immediately after the baby is born. Oxytocin 10 IU IM or IV is the first choice. Heat-stable carbetocin is an alternative where oxytocin quality cannot be assured.
  • Where no injectable uterotonic can be given safely (for example a home birth with a community health worker), oral misoprostol (400 or 600 micrograms) is an option per national programme.
  • Delay cord clamping for at least 1 minute unless the baby needs resuscitation.
  • After the placenta: check the uterus is firm by feeling the abdomen, and check again regularly over the first hours.
  • Do not give ergometrine to women with high BP or pre-eclampsia (lesson 3).

Detect: measure, do not guess

Place a calibrated drape (or another collection device) under the woman straight after birth and read it at intervals during the first hour. Record pulse and BP at the same time. Signs of shock: fast weak pulse, low BP, pallor, sweating, fast breathing, confusion, little urine.

Act: the MOTIVE first-response bundle

Bundle from WHO recommendations on assessment of postpartum blood loss and use of a treatment bundle (2023); TXA from the WHO recommendation on tranexamic acid (2017). Start all the steps together; a team works faster than one person.
StepWhat to do
M: MassageRub the uterus through the abdomen until it is firm; expel clots
O: OxytocicIV oxytocin infusion per protocol; other uterotonics (misoprostol, ergometrine if BP is normal) if bleeding continues
T: Tranexamic acid1 g IV over 10 minutes, as soon as possible and within 3 hours of birth; a second 1 g if bleeding continues after 30 minutes or restarts within 24 hours
I: IV fluidsLarge-bore IV line; crystalloid (normal saline or Ringer's lactate); take blood for Hb and cross-match if possible
V: Vaginal examinationLook for tears and bleeding from the cervix and vagina; check the placenta is complete; empty the bladder
E: EscalateStill bleeding after the bundle: call senior help, bimanual uterine compression, transfer to a facility that can transfuse and operate

Think of the causes

A soft uterus (atony) is the commonest cause. Others are tears of the cervix, vagina or perineum, a retained placenta or pieces of it, a ruptured or inverted uterus, and a clotting problem. A firm uterus with ongoing bleeding means look for a tear.

If you must transferKeep her warm and lying flat. Send a written note of blood loss, vital signs and every dose given. A non-pneumatic anti-shock garment, where available, can be used as a temporary measure while you wait for or during transfer.

Source: WHO recommendations for the prevention and treatment of postpartum haemorrhage (2012); WHO, FIGO and ICM consolidated PPH guideline (2025).

Worked case 2: Bleeding at a health post

Mrs L gave birth at a health post 20 minutes ago. She had oxytocin 10 IU IM. The drape now reads 350 mL. Her pulse has risen from 84 to 112 and BP is 96/60. The uterus feels soft.

Is this PPH?
Answer: Yes. 300 mL or more with abnormal vital signs (fast pulse, falling BP) meets the 2025 criteria. Do not wait for 500 mL.
What do you do in the next 15 minutes?
Answer: Call for help and start everything at once: uterine massage, IV oxytocin, TXA 1 g IV over 10 minutes, IV crystalloid, examine for tears and check the placenta, empty the bladder. If bleeding continues: bimanual compression and urgent transfer.
Case: Mrs K, retained placenta

Mrs K, 29, has given birth to her fourth baby at a health centre. Oxytocin 10 IU was given. Thirty minutes later the placenta has not delivered and she is bleeding steadily. The drape reads 550 mL. Pulse 108, BP 100/64. The nearest hospital is 90 minutes away.

Does she have PPH, and what is the likely cause?

Yes: measured loss over 500 mL. The likely cause is the retained placenta, which stops the uterus contracting.

What do you do now?

Call for help. Start the bundle: massage, IV oxytocin infusion, TXA 1 g IV over 10 minutes, IV fluids, examine for tears, empty the bladder. Try controlled cord traction once if trained. If the placenta does not deliver or bleeding continues, transfer urgently with a health worker, IV fluids running and a written record. Manual removal of the placenta needs a skilled provider, pain relief and a prophylactic antibiotic (lesson 7).

Key points
  • Oxytocin 10 IU IM or IV for every woman straight after the birth.
  • Measure blood loss; act at 500 mL, or at 300 mL with abnormal vital signs.
  • MOTIVE bundle together: massage, oxytocic, tranexamic acid, IV fluids, vaginal examination, escalate.
  • TXA 1 g IV within 3 hours of birth; repeat after 30 minutes if still bleeding.
  • Still bleeding: bimanual compression and urgent transfer.
Lesson 7 of 8 · about 30 minutes

Maternal sepsis

By the end of this lesson you can
  • Define maternal sepsis and recognise it early.
  • Give first treatment and refer.
  • Use the WHO measures that prevent infection around birth.

WHO defines maternal sepsis as a life-threatening condition in which infection causes organ dysfunction during pregnancy, childbirth, after an abortion, or after birth (WHO statement on maternal sepsis, 2017). It is one of the leading direct causes of maternal death, and many deaths follow a delay in noticing that a woman with an infection is getting worse.

Where the infection comes from

  • The uterus: infection of the membranes in labour (chorioamnionitis) or of the lining after birth (endometritis), often after prolonged rupture of membranes, long labour, many vaginal examinations, retained products or a caesarean.
  • After an unsafe or incomplete abortion.
  • Wound, breast (mastitis or abscess), urinary tract or pneumonia.
  • Malaria, HIV-related infections and TB can also cause sepsis in pregnancy.

Recognise it

Infection plus any sign in the right-hand column: treat as sepsis. Adapted from WHO MCPC (2017) and the WHO statement on maternal sepsis (2017).
Look for infectionLook for organ dysfunction (sepsis)
Fever 38 °C or more (or a low temperature), chillsFast breathing or low oxygen
Foul-smelling vaginal discharge or lochiaFast pulse, low BP, cold hands, slow capillary refill
Tender uterus, lower abdominal painConfusion, drowsiness
Red, painful wound or breast; burning urine; coughLittle or no urine; jaundice
Think sepsisFever, or feeling very unwell, in pregnancy or after birth or abortion: check pulse, BP, breathing rate, temperature and consciousness every time. A normal temperature does not rule out sepsis.

Act

  • ABCDE (see the Basic emergency care course): oxygen if breathing is fast or oxygen is low; IV line and fluid if signs of shock.
  • Give the first dose of IV or IM antibiotics before transfer, following your national protocol. WHO suggests ampicillin plus gentamicin for chorioamnionitis, and clindamycin plus gentamicin for endometritis after birth (WHO 2015).
  • Test for malaria where it occurs and treat if positive.
  • Refer urgently. Retained products, an abscess or a uterus that needs surgery cannot be treated with antibiotics alone.
  • The baby of a mother with infection around birth is at risk of sepsis too: check the baby for danger signs (lesson 5).

Prevent it

  • Hand hygiene and clean birth practices at every birth.
  • Vaginal examinations only when needed: in active labour, WHO suggests every 4 hours.
  • Prophylactic antibiotics for caesarean section (before the skin incision), manual removal of the placenta, and third- or fourth-degree perineal tears.
  • WHO does not recommend routine antibiotics after an uncomplicated vaginal birth or an episiotomy, or routine perineal shaving.

Source: WHO recommendations for prevention and treatment of maternal peripartum infections (2015); WHO statement on maternal sepsis (2017).

Worked case 2: Sick after an abortion

Ms N, 20, comes with lower abdominal pain and fever 4 days after an abortion done outside a health facility. Temperature 38.8 °C, pulse 124, BP 88/56, breathing 28 per minute. The vaginal discharge smells bad.

What is happening?
Answer: Sepsis after an unsafe abortion, with signs of shock. She may have retained products or an injury to the uterus.
What do you do?
Answer: ABCDE, oxygen, IV fluids for shock, first doses of IV antibiotics per protocol, and urgent transfer to a facility that can evacuate the uterus and operate. Treat her without judgement: fear of blame delays care.
Case: Mrs P, day 4 after birth

Mrs P gave birth at home 4 days ago after a 2-day labour; her waters broke a day before the birth. She has fever and lower abdominal pain. Temperature 38.6 °C, pulse 118, BP 104/68, breathing 24 per minute, alert. The uterus is tender and the lochia smells bad.

What is the likely diagnosis, and is it sepsis?

Endometritis (infection of the uterus) after prolonged rupture of membranes and a long labour. Her fast pulse and breathing are warning signs: treat as possible sepsis and do not wait for her BP to fall.

What do you do before she leaves?

IV line and fluids, first dose of antibiotics per national protocol (clindamycin plus gentamicin is a WHO-suggested regimen for endometritis), malaria test where relevant, and urgent referral. Check the baby for danger signs and keep breastfeeding if she can.

Key points
  • Maternal sepsis is infection plus organ dysfunction in pregnancy, birth, after abortion or after birth.
  • Check pulse, BP, breathing, temperature and consciousness in every woman with fever or who feels very unwell.
  • First dose of antibiotics and IV fluids before transfer; refer urgently.
  • Prevent: clean birth, fewer vaginal examinations, prophylactic antibiotics for caesarean, manual removal and severe tears.
Lesson 8 of 8 · about 35 minutes

The newborn at birth: essential care and the golden minute

By the end of this lesson you can
  • Give essential newborn care in the first hour.
  • Help a baby who does not breathe: dry, stimulate, and start bag-and-mask ventilation within one minute.
  • Know when to stop resuscitation and when to refer.

Around one in ten babies needs some help to start breathing, and a small number need ventilation with a bag and mask. Most can be saved by a prepared health worker with simple equipment. Every birth attendant should be ready for this at every birth.

Prepare before every birth

  • A warm room, free of draughts; two clean dry cloths; a cap.
  • A self-inflating bag with newborn masks (sizes for term and preterm babies), checked to work.
  • A suction device; cord ties or clamps and clean scissors.
  • A helper who knows what to do, and a plan for referral.

Essential newborn care in the first hour

  1. Dry the baby thoroughly at once, wiping the face and body, and remove the wet cloth. Look at breathing while you dry.
  2. Breathing well or crying: place the baby skin-to-skin on the mother's chest and cover both.
  3. Delay cord clamping for at least 1 minute (unless the baby needs ventilation).
  4. Help the mother start breastfeeding within the first hour.
  5. After the first feed: eye care per national protocol, vitamin K 1 mg IM, weigh, examine, and birth-dose vaccines on the national schedule. Delay the first bath for at least 24 hours.

The golden minute: a baby who does not breathe

Adapted from WHO Guidelines on basic newborn resuscitation (2012) and Helping Babies Breathe principles.
IfThen
Not breathing or gasping after dryingKeep warm; clear the airway only if mouth or nose is blocked by secretions; rub the back two or three times
Still not breathing wellClamp and cut the cord, move to a warm flat surface and start bag-and-mask ventilation within 1 minute of birth, with room air
VentilatingHead slightly extended; firm mask seal over chin, mouth and nose; watch the chest rise with each breath. About 40 breaths a minute
Chest not risingReposition the head, reapply the mask, clear the airway, squeeze harder
After about 1 minute of ventilationCheck heart rate and breathing. Breathing well: stop, skin-to-skin, watch closely. Not breathing: continue and call for help
Do notIn babies born through clear fluid who start breathing on their own, do not suction the mouth or nose. Do not hang babies upside down, slap them or put them in cold water.

When to stop

WHO advises stopping resuscitation if there is no detectable heart rate after 10 minutes of effective ventilation, and if the heart rate stays below 60 per minute with no breathing after 20 minutes. Support the family and record what happened.

After resuscitation

Any baby who needed ventilation is at risk: keep skin-to-skin, check breathing, temperature and feeding often, and refer to a facility that can care for sick newborns. Small babies (under 2.0 kg) need kangaroo mother care, starting as soon as possible after birth, and closer follow-up (see the sick young infant protocol).

Source: WHO Guidelines on basic newborn resuscitation (2012); WHO Essential newborn care course; WHO recommendations on maternal and newborn care for a positive postnatal experience (2022); WHO recommendations for care of the preterm or low-birth-weight infant (2022).

Worked case 2: A small baby born early

Mrs S gives birth at 34 weeks at a health centre. The baby cries after drying and weighs 1.8 kg. The room is cool.

What does this baby need first?
Answer: Skin-to-skin contact on the mother's chest (kangaroo position), a cap and a cover, and breastfeeding support. Delay cord clamping, give vitamin K and delay the bath.
Does the baby need referral?
Answer: Yes: a baby under 2.0 kg needs care at a facility able to support small babies, with kangaroo mother care continued during transfer and feeding checked often.
Case: Floppy and not breathing

You attend a birth at a health centre. The baby is born after a long second stage, is floppy and is not breathing. You dry the baby and rub the back. After 30 seconds the baby is still not breathing. You have a bag and mask.

What do you do now?

Clamp and cut the cord, place the baby on a warm flat surface, position the head slightly extended and start bag-and-mask ventilation with room air so that it begins within 1 minute of birth. Watch for the chest to rise; about 40 breaths a minute.

After 1 minute of ventilation the baby has a heart rate but is gasping. What next?

Continue ventilation, call for help, and check again. When the baby breathes well, stop ventilation, place skin-to-skin and monitor closely. Refer the baby for observation and care after resuscitation.

Key points
  • Prepare for every birth: warm room, dry cloths, working bag and mask, a helper.
  • Dry at once, skin-to-skin, delayed cord clamping, breastfeeding in the first hour, vitamin K.
  • Not breathing after drying and rubbing: bag-and-mask ventilation within 1 minute, with room air.
  • Stop if no heart rate after 10 minutes of effective ventilation.
  • Refer babies who needed ventilation or weigh under 2.0 kg; kangaroo mother care.
Final quiz

Quiz and CPD certificate

Answer all 15 questions, then press Mark. You need 12 or more to pass. You can look back at the lessons: the aim is learning. A pass gives a printable certificate of completion for 4 hours of self-directed learning; you need a free account, signed in, to issue it.

Sources

  1. World Health Organization. WHO recommendations on antenatal care for a positive pregnancy experience. 2016 (ISBN 9789241549912).
  2. World Health Organization. WHO recommendations on maternal and newborn care for a positive postnatal experience. 2022 (ISBN 9789240045989).
  3. World Health Organization. WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia. 2011 (ISBN 9789241548335).
  4. World Health Organization. WHO recommendations on drug treatment for non-severe hypertension in pregnancy. 2020.
  5. World Health Organization. Managing complications in pregnancy and childbirth: a guide for midwives and doctors, 2nd edition. 2017.
  6. World Health Organization. Guideline on haemoglobin cutoffs to define anaemia in individuals and populations. 2024.
  7. World Health Organization. Pregnancy, childbirth, postpartum and newborn care: a guide for essential practice, 3rd edition. 2015.
  8. World Health Organization. WHO recommendations for the prevention and treatment of postpartum haemorrhage. 2012 (ISBN 9789241548502).
  9. World Health Organization. WHO recommendation on tranexamic acid for the treatment of postpartum haemorrhage. 2017 (ISBN 9789241550154).
  10. World Health Organization. WHO recommendations on the assessment of postpartum blood loss and use of a treatment bundle for postpartum haemorrhage. 2023 (ISBN 9789240085398).
  11. World Health Organization, International Federation of Gynecology and Obstetrics and International Confederation of Midwives. Consolidated guideline on the prevention, diagnosis and treatment of postpartum haemorrhage. 2025. Launched October 2025; diagnostic threshold taken from the launch summary.
  12. World Health Organization. WHO recommendations for prevention and treatment of maternal peripartum infections. 2015 (ISBN 9789241549363).
  13. World Health Organization. Statement on maternal sepsis. 2017 (WHO/RHR/17.02).
  14. World Health Organization. Guidelines on basic newborn resuscitation. 2012 (ISBN 9789241503693).
  15. World Health Organization. WHO recommendations for care of the preterm or low-birth-weight infant. 2022.
  16. World Health Organization. Medical eligibility criteria for contraceptive use, 5th edition. 2015 (ISBN 9789241549158).
  17. World Health Organization. Report of a WHO technical consultation on birth spacing. 2005.
Adapted from WHO guidance; not endorsed by WHO. This page paraphrases and adapts the WHO publications listed under Sources, which are licensed CC BY-NC-SA 3.0 IGO; the adapted text is shared under the same licence for non-commercial education. Reasoning GP is not affiliated with WHO or any other organisation named here. Use it alongside your national guidelines, essential medicines list and formulary, and your clinical judgement. Doses are given only where they come from a WHO source; otherwise follow your national guideline or formulary.