← Full hand pain algorithm
Reasoning GP · Algorithm · 1-page summary

Hand pain in adults

For: adults with hand or wrist pain, swelling, stiffness, numbness or reduced grip. Not for: children (local paediatric pathway); one painful finger, widespread joint pain or Raynaud's alone (their own algorithms).
Reviewed October 2026 · next review April 2027
NICE NG100NG226NG219NG12BSSH
Core rule: exclude the septic joint, tendon-sheath infection, ischaemia and injection or bite injuries before any reassurance. Persistent synovitis → urgent rheumatology, without waiting for blood results.

0Stop — call 999 now — before any history

  • Cold, painful, pale/blue or mottled hand or digit with sensory or motor change → 999 / immediate ED. An absent radial pulse is not required; Allen's test must not delay referral.
  • Necrotising fasciitis (rapidly spreading redness, pain out of proportion, bullae, crepitus, toxicity) or compartment syndrome after trauma or casting (pain on passive stretch, tense swelling) → 999. A palpable pulse does not exclude it.
  • Shocked, septic or rapidly deteriorating, or threatened limb → 999. Never delay transfer for community bloods or imaging.

1Triage by pattern — stiffness and distribution

FindingPoints to → action
Hot swollen jointSeptic until excluded → Same-day ED
Soft MCP/PIP swellingStiffness >30 min → Urgent rheumatology
Bony nodes, thumb baseStiffness <30 min: OA, primary care
Night median tinglingCTS; wasting → Urgent surgical
Radial styloid; lockingde Quervain's, trigger finger: primary care

2Screen — one row is enough

  • Septic joint or flexor sheath infection (fusiform, held flexed, pain on passive extension) → Same-day ED / hand surgery
  • Grease or paint-gun injection, even a tiny wound → Immediate hand / plastics; do not explore or close.
  • Fight-bite over a knuckle, or bite into joint, tendon or bone → Same-day ED / hand surgery; do not close.
  • Open fracture, dislocation, rotation, tendon or neurovascular injury → Same-day ED / hand trauma
  • Gout or pseudogout if sepsis not reasonably excluded, or unwell → Same-day ED / hand surgery
  • Lump increasing in size → consider Urgent ultrasound ≤2 weeks (NG12); sarcoma suggested → suspected-cancer pathway; never biopsy.

3Assess — only once blocks 0–2 are answered

☐ Joints, symmetry, stiffness  ☐ Swelling: bony, soft or fusiform  ☐ Tinel's, Phalen's, Finkelstein's, grind  ☐ Grip, thenar wasting, sensation, capillary refill  ☐ Psoriasis, IBD, gout, diabetes, thyroid  ☐ Vibrating tools; fluoroquinolones

Inflammatory: CRP/ESR, FBC, RF + anti-CCP; normal results never delay referral. Gout: urate; if <360 µmol/L in a flare, repeat ≥2 weeks after it settles. Not routine: X-ray for typical OA, MRI, ANA; NCS before a splint trial.

4Classify — only if the screen is negative

  • Inflammatory — bilateral MCP/PIP synovitis sparing DIPs; nail pitting → Urgent rheumatology (NG100), even with normal bloods.
  • OA — Heberden's/Bouchard's nodes, 1st CMC squaring; age ≥45, activity-related. X-ray only if atypical.
  • Carpal tunnel — night or activity median paraesthesia; NCS if uncertain, atypical, severe or motor deficit.
  • Tendon — de Quervain's (Finkelstein's positive); trigger finger (A1 pulley, locking).
  • Other — gout/CPPD (urate supports, crystals confirm); Dupuytren's; HAVS (vibration, cold blanching).
  • Uncertain hot swollen joint — say so → Same-day hospital. Treat as septic until excluded.

5Treat today — doses: NICE/SPC, BNF, local formulary

  • Hand OA: exercise, hand therapy; consider a topical NSAID, then an oral NSAID with a PPI after GI, renal, liver and CV risk. No routine paracetamol or weak opioids.
  • Carpal tunnel: neutral night wrist splint trial; consider steroid injection if trained.
  • Gout flare (septic joint reasonably excluded): NSAID, colchicine or a short oral steroid, by renal, hepatic, CV/GI risk and interactions.

6Refer routinely

  • Carpal tunnel failing conservative care → surgery; thenar wasting, objective weakness, severe/progressive sensory loss → Urgent.
  • Thumb-base OA failing conservative treatment; de Quervain's failing steroid injections; trigger finger grade III–IV; Dupuytren's affecting function → orthopaedics.
  • OA, mild–moderate carpal tunnel, tendinopathy → hand therapy. HAVS → occupational health.

7Never reassure by

  • Normal CRP/ESR or negative RF or anti-CCP when synovitis persists.
  • A tiny puncture wound after a grease or paint gun, or a bite over a knuckle.
  • A palpable radial pulse with a cold, pale digit, or a palpable pulse after trauma or casting.
  • A gout history in a hot swollen joint: exclude sepsis first.
  • A normal serum urate during a flare.
  • A normal X-ray in early RA.

8Safety-net — say it, then document it

999 “Call 999 for rapidly spreading redness or swelling with severe pain or feeling very unwell, a cold, pale, blue or mottled hand or finger with numbness or weakness, or severe worsening pain with tight swelling after an injury or in a plaster cast.”

Same day “Go to A&E or the hand unit today for a hot swollen joint, a swollen, bent, very tender finger, any grease or paint-gun injury, or a bite or punch wound over a knuckle. See us today for severe worsening pain, loss of hand function, new numbness or weak grip, or feeling unwell with joint pain.”

✓Safe to leave primary care only if — all five, documented

No block 0–2 feature (sepsis, ischaemia, injection, bite, fracture) Joint pattern, stiffness and neurovascular status recorded Synovitis looked for; urgent rheumatology sent if persistent Cause named, or uncertainty stated, with a review date Safety-net given and documented
Summary of the full Reasoning GP hand pain algorithm, which holds the detail, examination, gout and DMARD management, lifestyle and evidence. Sources: NICE NG100, NG226, NG219, NG12 (updated April 2026); BSSH; Control of Vibration at Work Regulations. Clinical reference — follow local hand-surgery and rheumatology pathways and check doses: NICE/SPC, BNF.