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Reasoning GP · Algorithm · 1-page summary

Rash with fever in a child

For: children with fever and a rash in primary care; the NICE traffic light is validated under 5, same principles to 16. Not for: fever without rash (fever in children algorithm); immunocompromised children follow their specialist pathway.
Reviewed October 2026 · next review April 2027
NICE NG143NICE NG240UKHSANICE CKS
Core rule: look at the whole child before the rash. A non-blanching rash with fever is meningococcal disease until proved otherwise — and the glass test cannot exclude it.

0Stop — call 999 now — do not delay transfer

  • Non-blanching rash with fever, or an ill child with a rash → 999; meningococcal disease strongly suspected → IM/IV benzylpenicillin or ceftriaxone unless it delays transfer (dose per NICE/SPC (children: BNFC)).
  • Shock (mottled, cold hands and feet, weak pulse), suspected meningitis, seizure, respiratory compromise → 999
  • iGAS features — pain out of proportion, rapidly spreading redness, toxic child → 999

1Triage — NICE NG143 traffic light

ColourAction
RedUrgent paediatric assessment (generally ≤2 h); 999 if life-threatening
Under 3 monthsTemperature 38°C or more → red
AmberFace-to-face; same-day paediatrics if concerning, else safety-net and review
GreenHome with written safety-net

2Screen

  • Fever for 5 days or more with red eyes, lips, rash, swollen hands or feet → Same-day paediatrics (Kawasaki)
  • Blisters, skin pain, mucosal involvement (eczema herpeticum, SJS) → Same-day
  • Complicated chickenpox, neonate or immunosuppressed with chickenpox or measles → Same-day
  • Unexplained petechiae, pallor, hepatosplenomegaly → immediate paediatric assessment

3Assess

☐ Temperature, HR, RR, SpO₂, capillary refill, hydration  ☐ Undress fully; check conjunctivae, palms, soles, mouth  ☐ Blanching or not  ☐ Vaccination (MMR/MMRV)  ☐ Contacts, pregnant household members  ☐ Urine if under 5 with no source

Do not: delay transfer for tests, or rely on the glass test.

4Classify

  • Measles — cough, coryza, conjunctivitis, Koplik spots, rash from the face down → notify, isolate.
  • Scarlet fever — sore throat, sandpaper rash, strawberry tongue → treat, notify.
  • Chickenpox — itchy vesicles in crops → supportive; no NSAIDs.
  • HFMD · slapped cheek · roseola — well child → supportive.
  • Kawasaki — fever for 5 days or more + mucocutaneous signs → same-day.
  • Uncertain — reassess; any doubt about a non-blanching rash → 999.

5Treat today — doses: NICE/SPC, BNFC, local formulary

  • Scarlet fever: phenoxymethylpenicillin for 10 days; allergy → macrolide per UKHSA.
  • Chickenpox: paracetamol, fluids, emollient; aciclovir not routine in healthy children.
  • Antipyretics for distress only; not both at once; no tepid sponging.
  • Notify measles, scarlet fever, iGAS, rubella, meningococcal on suspicion.

6Exclusion (UKHSA)

  • Chickenpox at least 5 days and until all spots crusted · measles 4 days from rash · scarlet fever 24 hours after antibiotics.
  • HFMD, slapped cheek, roseola: none if well. Pregnant contacts → midwife or GP.

7Never reassure by

  • A rash that blanches in an ill child.
  • A negative glass test.
  • A fall in temperature after paracetamol or ibuprofen.
  • Absence of neck stiffness in an infant.
  • "Viral rash" when fever has lasted 5 days or more.
  • Ibuprofen in chickenpox.

8Safety-net — verbal and written

999 “Call 999 if the rash does not fade when a glass is pressed on it, your child is floppy, drowsy or hard to wake, has a fit, struggles to breathe, or has cold hands and feet with pale or mottled skin.” Same day “Contact us the same day if the fever lasts 5 days or more, your child is not drinking, or chickenpox spots become red, hot and very painful.”

Remote consultation: any non-blanching rash or red feature converts to face-to-face or emergency care.

✓Safe to manage in primary care only if — all five, documented

No red feature; rash blanches; child looks well Whole skin examined, observations recorded Diagnosis named; notified if required Exclusion and vulnerable contacts advised Written safety-net; review if amber
Summary of the full Reasoning GP rash with fever in a child algorithm, which holds the detail and evidence. Sources: NICE NG143; NICE NG240; UKHSA children and young people settings guidance, scarlet fever and measles guidance; NICE CKS. Clinical reference — check doses in the SPC and your local formulary.