RCGP SCA Algorithm — UK Primary Care
Most ear discharge is otitis externa or a perforated acute otitis media. The dangerous few are necrotising otitis externa, cholesteatoma, mastoiditis, intracranial spread and CSF leak. For ear pain without discharge see the Otalgia algorithm.
Necrotising otitis externa is a Pseudomonas osteomyelitis of the skull base. It looks like simple otitis externa at first; the clues are the host (diabetes, immunosuppression, older age), pain out of proportion and failure of topical treatment. Hospital teams arrange imaging, culture and prolonged antibiotics, and biopsy may be needed because malignancy can mimic it (ENT UK). Signs of basal skull fracture are a NICE NG232 indication for CT head within 1 hour.
The classic description of cholesteatoma is painless, smelly, scanty discharge with hearing loss that keeps coming back despite drops. Neomycin and other topical agents can cause contact dermatitis that mimics a treatment failure.
If the canal is too swollen or full of debris to see the drum, assume it may be perforated and choose non-ototoxic treatment. Granulation tissue in the canal of a diabetic patient with severe pain is necrotising otitis externa until proved otherwise.
Swabs do not change initial management of straightforward otitis externa and should never delay treatment, but they guide therapy when first-line drops fail and identify fungal infection or resistant Pseudomonas.
Otitis externa and AOM can coexist, and discharge from a perforated drum can cause a secondary otitis externa. Cholesteatoma is locally destructive — it erodes ossicles, the facial nerve canal and the skull base, and can lead to meningitis or brain abscess — so persistent discharge needs ENT assessment rather than repeated drops.
Aural toilet (microsuction or dry mopping) is often what makes topical treatment work — drops cannot reach skin covered in debris. Most perforations from AOM heal within weeks; a perforation that persists needs ENT review for repair and to exclude cholesteatoma.
Next steps: see Otitis media and otitis externa
Aminoglycoside drops (neomycin, gentamicin, framycetin) are ototoxic if they reach the middle ear; ENT UK advises avoiding them with a perforation or patent grommet unless specifically advised. Quinolone ear drops are not ototoxic. Acetic acid and topical antibiotic–steroid drops have similar cure rates at 7 days, but acetic acid is less effective when treatment has to continue beyond a week.
Water exposure and trauma to the canal skin are the main drivers of otitis externa; preventing them avoids recurrence and repeated courses of drops.
Recurrent courses of drops without re-examination are the commonest way to miss cholesteatoma and necrotising otitis externa. Document whether the drum was seen and intact, which drops were chosen and why.