Evidence-Based Medicine

The numbers behind the recommendations

Search the question once and fire it into PubMed, Cochrane, TRIP, NICE/CKS, BMJ Best Practice, GPevidence or TheNNT β€” or get an instant AI synthesis and a one-click handoff to OpenEvidence. Plus the three sites every UK GP should bookmark, and our own per-case "what's the evidence?" summary.

Evidence searchAsk once β€” search every source

Type a clinical question, then either get an instant AI synthesis, send it straight to OpenEvidence, or launch it into any UK/global evidence database below. Each opens in a new tab with your question pre-filled.

🩺 Ask OpenEvidence β†—

OpenEvidence is free but requires a one-time clinician sign-in. We copy your question to the clipboard and open the ask page β€” just paste (⌘/Ctrl-V) and send.

Or launch into a specific database

Essential bookmarksThree sites we recommend

πŸ‡¬πŸ‡§ UK primary care

GPevidence

Evidence summaries for UK general practice β€” short, scannable, with practical "so what" for the consultation. Run by UK GPs.

UK focusFree
Open gpevidence.org β†—
πŸ“Š NNT / NNH

TheNNT

Number-needed-to-treat and number-needed-to-harm for hundreds of interventions, displayed as colour-coded one-page summaries. Excellent for shared decisions.

VisualFree
Open thennt.com β†—
πŸ€– AI-assisted

OpenEvidence

Free AI-assisted evidence synthesis (US-developed). Ask a clinical question, get cited synthesis from the literature. Useful for uncommon presentations.

AI searchFree for clinicians
Open openevidence.com β†—

High-yield evidenceThe 50 interventions GPs are asked about most

Each card gives the bottom-line verdict, the key numbers (NNT/NNH or effect), a written summary of what the evidence actually shows, the practical UK take, and a link to read more. Search or filter by system and by verdict.

In every case"What's the evidence?" block

Every Reasoning GP full case will carry an Evidence Summary block linking each major management step to the underlying NNT/NNH, the primary RCT, and the NICE CKS evidence statement. Rolling out across the case library in Q2 2026.

View the case library β†’