Sexual Health · Full case

Vaginal Discharge & STI Screen

BASHHBV · candida · STI · PIDCervical red flags
VD
Vaginal Discharge & STI Screen · Clinical Reasoning Framework v2
GP & SCA · BASHH · BV · Candida · Chlamydia/Gonorrhoea · Trichomonas · PID · Partner notification · Safeguarding · Cervical red flags
Discharge ≠ STIThe two commonest causes of vaginal discharge — bacterial vaginosis and candida — are NOT sexually transmitted. But discharge can also signal chlamydia, gonorrhoea, trichomonas or PID, so a sexual history and risk assessment are essential before assuming it's "just thrush"
BV = fishy, thin, greyBacterial vaginosis: thin grey-white homogeneous discharge with a fishy odour, raised vaginal pH (>4.5), no itch/soreness. Overgrowth of anaerobes; not an STI. Treat with metronidazole; often recurs
Candida = itch, white, curdyVulvovaginal candidiasis: thick white "cottage cheese" discharge with vulval itch and soreness, normal pH. Treat with an azole (clotrimazole pessary/cream or oral fluconazole). Recurrent (≥4/yr) → induction + maintenance and check for diabetes
Test of choice: NAATChlamydia and gonorrhoea are diagnosed by nucleic acid amplification test (NAAT) — a vulvovaginal self-swab is the recommended sample in women. Offer a full STI screen (incl. HIV and syphilis serology) where there is risk
Chlamydia = commonest STIChlamydia is the most common bacterial STI in the UK and is often asymptomatic; untreated it can cause PID, ectopic pregnancy and tubal infertility. Treat with doxycycline (azithromycin in pregnancy); partner notification is essential
PID = treat on clinical suspicionPelvic inflammatory disease (pelvic/lower abdominal pain, deep dyspareunia, abnormal bleeding/discharge, adnexal/cervical motion tenderness) — have a low threshold and treat empirically; delay risks infertility. Exclude/cover ectopic and pregnancy
Bleeding = examine the cervixPost-coital or intermenstrual bleeding, or discharge with a suspicious-looking cervix, must not be assumed infective — examine the cervix; a clinically suspicious cervix warrants urgent referral for suspected cervical cancer (NICE NG12), regardless of smear history
Safeguarding alwaysIn anyone under 16 (or 16–17 with power imbalance), assess competence (Fraser), capacity to consent to sex, and child sexual exploitation/abuse. Document consent, partner age and circumstances; involve safeguarding leads where there is concern
📋 Clinical Stem — Vaginal Discharge & STI Screen
A 24-year-old woman with three weeks of altered vaginal discharge and one episode of bleeding after sex, who "just wants some thrush treatment" and is reluctant to be examined
Aisha Rahman, 24, attends asking for thrush treatment. She has had three weeks of increased vaginal discharge, which she describes as different from her usual thrush — more watery, and she's noticed a smell. On direct, sensitive questioning she mentions one episode of light bleeding after sex last week. She has a new partner over the past two months and they have not consistently used condoms; her first cervical screening test, three months ago after her invitation at 24½, was normal (HPV negative). She is keen to be given thrush treatment and leave, and is hesitant about an examination or swabs. She is otherwise well, with no fever or severe pain.
This stem tests the ability to: take a non-judgmental sexual history and risk assessment; recognise that "different from usual thrush" plus odour and a new partner shifts the differential toward BV and STIs rather than candida; offer appropriate testing (self-taken vulvovaginal NAAT for chlamydia/gonorrhoea, and a full STI screen) and explain why; recognise post-coital bleeding as a feature that mandates examining the cervix and considering the NICE NG12 cervical cancer pathway if the cervix looks suspicious (not simply reassuring on the basis of a recent normal smear); manage PID risk; and handle partner notification, safeguarding and the patient's reluctance to be examined with sensitivity. The SCA challenge is balancing her wish for a quick fix against the need to test and examine.
Scenario A — Bacterial vaginosis Thin grey discharge, fishy odour, no itch, raised pH. Metronidazole; advise on recurrence triggers (douching, etc.); not an STI but consider STI risk.
Scenario B — Vulvovaginal candidiasis Thick white discharge, vulval itch/soreness, normal pH. Azole treatment; if recurrent (≥4/yr) induction + maintenance and screen for diabetes.
Scenario C — STI (chlamydia/gonorrhoea/trichomonas) New partner, inconsistent condoms, altered discharge ± dysuria/bleeding. NAAT self-swab + full STI screen; treat; partner notification; test of cure where indicated.
Scenario D — Pelvic inflammatory disease Lower abdominal/pelvic pain, deep dyspareunia, abnormal bleeding, cervical motion/adnexal tenderness. Treat empirically; exclude ectopic/pregnancy; safety-net; partner treatment.
Scenario E — Cervical red flag Post-coital or intermenstrual bleeding; a friable/irregular cervix on examination. Examine the cervix; urgent referral for suspected cervical cancer (NG12) if suspicious — a recent normal smear does not exclude it.
Key variables to adapt for Symptom character (BV vs candida vs STI); sexual history & risk (new/multiple partners, condoms, MSM partner, sex work); bleeding (PCB/IMB → examine cervix; NG12); pregnancy (drug choice, ectopic, screen); age & safeguarding (<16, 16–17, exploitation); recurrence; systemic features/PID; partner notification; the patient's reluctance and need for confidentiality.
Steps:
1
Step 1
History — Characterise the Discharge · Sexual History · Bleeding · Safeguarding · ICE
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The history has three jobs: characterise the discharge (which points toward BV, candida or an STI), take a sensitive sexual history and risk assessment (because discharge is not always benign), and pick up the features that change everything — abnormal bleeding (cervical red flag), pelvic pain (PID), pregnancy, and safeguarding concerns. Aisha's "different from usual thrush," the odour, the new partner and the post-coital bleeding are exactly the threads that move this away from a simple thrush prescription.
🎓 SCA framing — confidentiality, non-judgment, and a reason to test
"Everything we discuss is confidential. To give you the right treatment rather than guessing, I'd like to ask a few questions about your sexual health and, ideally, do some simple tests — including one you can do yourself. Is that okay?"
Aisha wants thrush treatment and is reluctant to be examined. The skill is to create a confidential, non-judgmental space, explain why testing matters (right treatment, the bleeding, partner health), and offer a self-taken swab to lower the barrier — without pressuring her.
1A — Characterise discharge, bleeding and pain
QuestionWhy it mattersChanges what?
🟢 OPEN QUESTION"Tell me about the discharge — what it's like, when it started, and what made you come in now." The character of the discharge narrows the cause. Thin grey + fishy odour, no itch → BV. Thick white + itch/soreness → candida. Watery/altered with odour, ± dysuria or bleeding, especially with a new partner → think STI. Aisha's "watery, with a smell, different from my usual thrush" already argues against simple candida.In SCA: capturing colour, consistency, odour, itch AND the patient's own comparison ("different from usual") is what distinguishes a real assessment from a reflex thrush prescription. Fishy/grey → BV; itchy/white → candida; altered + risk → STI
Associated symptoms"Any itch or soreness, pain passing urine, pain low down or during sex?"Itch/soreness favours candida; dysuria can occur with STIs (and urethritis); lower abdominal/pelvic pain and deep dyspareunia raise PID — which needs a low threshold to treat. Their presence or absence reshapes the differential and urgency.Changes: Itch → candida; dysuria → STI/urethritis; pelvic pain + dyspareunia → PID.PID features → empirical treatment
🚩 Abnormal bleeding"You mentioned bleeding after sex — has that happened more than once? Any bleeding between periods?"A pivotal safety thread. Post-coital and intermenstrual bleeding can be caused by chlamydia/cervicitis — but they are also red flags for cervical pathology. They mandate examining the cervix; a suspicious-looking cervix warrants urgent referral for suspected cervical cancer (NG12), and a recent normal smear does NOT exclude it.Changes: PCB/IMB → examine cervix; infective cause treated; suspicious cervix → NG12 urgent referral.Suspicious cervix → suspected cancer pathway referral (NG12)
Sexual history & risk"Can I ask about partners — when you last had sex, whether partners are male or female, condom use, and any new partners recently?"Risk assessment guides testing: new/multiple partners, inconsistent condoms, a partner from a high-prevalence group, MSM partner, or sex work raise STI probability and the scope of the screen (e.g. extra-genital swabs, HIV/syphilis serology). Aisha's new partner and inconsistent condoms place her at risk.Changes: Risk present → full STI screen (NAAT + HIV/syphilis); consider extra-genital sites by exposure.Full STI screen by risk/sites
Pregnancy & contraception"Is there any chance you could be pregnant? What contraception are you using?"Pregnancy changes drug choice (avoid some agents), raises the stakes of an STI (vertical transmission), and — with pain/bleeding — must prompt exclusion of ectopic. Contraception need is an opportunity (e.g. emergency contraception, LARC).Changes: Pregnancy → altered drugs, exclude ectopic, screen. Contraception need → address.Pregnancy alters treatment
🛡️ Age & safeguarding"How old is your partner? Do you feel safe and in control of what happens in the relationship?"In anyone under 16 (or 16–17 with a power imbalance), assess Fraser competence, capacity to consent, partner age/circumstances and any signs of child sexual exploitation or abuse. Coercion, age disparity, or grooming markers require safeguarding action. This is mandatory, not optional, in sexual-health consultations with young people.Changes: Under-16 / coercion / exploitation markers → safeguarding assessment and referral.Safeguarding pathway if concern
1B — Red flags
🚨

Red Flags — when discharge is not "just thrush"

Red flagWhy dangerousAction
Post-coital / intermenstrual bleeding, or a suspicious-looking cervixCan be infective (cervicitis) but is a recognised presentation of cervical cancer. A normal smear does not exclude cancer. The cervix must be visualised; a friable, irregular or contact-bleeding cervix needs urgent referral.Examine cervix; urgent suspected cervical cancer referral (NICE NG12) if appearance suspicious
PID — pelvic pain, deep dyspareunia, abnormal bleeding, cervical motion/adnexal tendernessDelayed treatment risks tubal infertility, ectopic pregnancy and chronic pain. Have a low threshold to treat empirically.Empirical PID antibiotics; exclude ectopic/pregnancy; partner treatment; safety-net
Pregnancy with pain/bleedingEctopic pregnancy is life-threatening and can mimic PID/STI symptoms; never attribute pain/bleeding in a possibly pregnant woman to infection without excluding ectopic.Pregnancy test; urgent assessment / EPU if ectopic possible
Systemic sepsis / tubo-ovarian abscessSevere PID with fever, severe pain, peritonism or a pelvic mass can become life-threatening.Same-day admission; IV antibiotics; gynaecology
Safeguarding — under 16, coercion, exploitation, FGM, abuseSexual-health presentations in young or vulnerable people may be the only window onto abuse or exploitation; missing it has lifelong consequences.Safeguarding assessment; involve safeguarding lead; document; refer as indicated
Possible disseminated/complicated gonococcal or syphilisUntreated gonorrhoea/syphilis can disseminate; resistant gonorrhoea needs specialist management and culture for sensitivities.GUM referral; culture for gonorrhoea sensitivities; treat per BASHH
1C — ICE
💭 Ideas
"What do you think is causing it — and what's made you feel it's thrush?"
Aisha has self-diagnosed thrush. Engaging her idea lets you gently introduce that the features she describes (odour, watery, different from usual, bleeding after sex) don't all fit thrush — opening the door to testing without making her feel doubted or judged.
😟 Concerns
"Is there anything you've been worried it might be?"
She may be quietly worried about an STI (given the new partner) but reluctant to say so, or embarrassed about examination. Naming the worry, and reassuring on confidentiality and non-judgment, often unlocks an honest history and consent to testing.
🎯 Expectations
"You were hoping for thrush treatment — can I explain why I'd like to check a couple of things first?"
Her expectation is a quick prescription. Naming it lets you offer a better deal: the right treatment based on a self-taken test, addressing the bleeding properly, and protecting her future fertility — framed as being on her side, not obstructing her.
1D — Psychosocial context
🤝 Embarrassment, stigma and the wish to be in and out quickly

Vaginal symptoms and sexual-health questions carry stigma and embarrassment, and many people present hoping for a quick, private fix — "just some thrush cream." A consultation that simply hands over the cream misses BV, STIs, PID and, occasionally, cervical pathology; one that interrogates or judges drives the patient away and damages trust. The work is to create a confidential, non-judgmental, unhurried space, explain why a few questions and a simple (often self-taken) test give the right answer, and respect autonomy if she declines — while being clear about the bleeding that does need looking at.

🔒 Confidentiality

Explicit reassurance about confidentiality (and its limits in safeguarding) is the foundation of an honest sexual history — especially for young people.

"Everything we talk about here is confidential. The only time I'd ever need to share anything is if I were worried about your safety — and I'd talk to you first."
🙅 Reluctance to be examined

Offer the self-taken vulvovaginal swab to lower the barrier; explain when an examination is genuinely needed (the bleeding) and let her retain control.

"For the infection tests you can take the swab yourself — it's just like inserting a tampon. The one thing I would like to look at, because of the bleeding after sex, is your cervix — but we can talk that through and you're always in control."
💬 Non-judgmental partner notification

Framing partner notification as routine and blame-free (and offered via the clinic/GUM) makes it acceptable and protects others.

"If a test is positive, we'd want to let recent partners know so they can be treated too — that can be done completely anonymously through the sexual-health service. It's routine and nobody is blamed."
⚕️ Future fertility framing

Linking testing to protecting her future fertility (untreated chlamydia → PID → tubal damage) gives a positive, personal reason to test.

"One reason I'm keen to test rather than guess is that some infections, if missed, can quietly affect fertility later — testing now is the best way to protect that."
1E — Psychosocial context: the person behind the discharge
🧭
Who is Aisha, and what is shaping what she tells you?
A sexual-health history is only as good as the trust in the room. What a patient discloses about partners, bleeding, coercion or previous infections depends on her age, culture, relationship, previous experiences of healthcare and what she fears the answer might mean. Exploring context is not a detour from the clinical task — it is how you get the information that decides the clinical task.
💞
The new relationship

A two-month relationship is often the point when condoms are dropped and when a positive STI result feels most threatening — "does this mean he's been unfaithful?" or "will he think I have?" Many patients avoid testing to avoid that conversation. Explain that chlamydia can be carried silently for months or years, so a positive result rarely tells you who acquired it from whom or when.

"Infections like chlamydia can sit quietly for a long time without symptoms, so a positive test doesn't tell us who had it first. It's about getting you both treated, not about blame."
🕌
Culture, faith and family

For some patients, sex outside marriage or a new relationship carries family, cultural or religious weight, and confidentiality from relatives (including relatives registered at the same practice, or who may see a prescription or letter) is a real concern. Do not assume — ask how she would like results and contact handled (which phone number, whether a message can be left, text vs call).

"How would you like us to get in touch about results? Is it okay to text this number, or would you rather we only call you directly?"
🛡️
Coercion and domestic abuse

Recurrent STIs, requests for repeated emergency contraception, a partner who controls contraception or condom use, or reluctance to be seen alone can signal intimate-partner violence or reproductive coercion. Ask routinely and privately, not only when there is a visible sign. If she discloses, the plan changes — safety, IDVA/local domestic abuse services, documentation that the partner cannot access, and care with partner notification.

"I ask everyone this: does anyone ever pressure you into sex, or stop you using contraception or condoms when you want to?"
🧒
Young people

Under-16s can consent to STI testing and treatment if Gillick competent, and to contraception if the Fraser criteria are met; confidentiality is maintained unless there is a risk of serious harm. Every under-18 needs a proportionate child sexual exploitation assessment (age and age of partner, gifts or money, alcohol or drugs, older "boyfriend", going missing, repeat STIs or emergency contraception). A child under 13 cannot consent to sexual activity in law (Sexual Offences Act 2003) — disclosure of sexual activity or an STI in an under-13 means a safeguarding referral every time.

"You can see me on your own and what we talk about stays private. The only time I'd need to share anything is if I thought you or someone else was at risk of serious harm — and I'd talk to you about it first."
⚕️
Previous experiences of examination

Reluctance to be examined may be embarrassment, but it may also reflect previous sexual trauma, vaginismus, FGM, or a painful previous speculum examination. Offering a self-taken swab, a clinician of her preferred gender, a chaperone, a smaller speculum, and explicit permission to stop are trauma-informed defaults, not concessions.

"Some people find examinations difficult for all sorts of reasons, and you don't have to tell me why. You're in control — we can stop at any point, and if today isn't right we can plan another time."
💼
Time, work and access

"I'm in a rush" is often real: an office job, a lunch-break appointment, the difficulty of getting back for results. Make the efficient path the safe path — self-swab and bloods today, results by text, the examination booked at a time that suits her (with a clear reason why it should not wait long), and direct booking or online self-sampling from the local sexual health service where available.

"I know you're short of time. If we do the swab and the blood test now, the results come to your phone — and we'll find a time that works for the examination this week."
🎓 SCA Checkpoint — Step 1TasksRelating to OthersGlobal Skills
Key phrases that score
"Has the bleeding after sex happened more than once? Any bleeding between periods?" — opens the cervical red-flag door.
"Everything's confidential — can I ask a few questions about your sexual health so I treat the right thing?" — enables the history.
"For the infection tests you can take the swab yourself." — lowers the barrier, respects autonomy.
Deductions
  • Prescribing thrush treatment without a sexual history or considering STI/BV
  • Ignoring post-coital bleeding / not examining the cervix
  • Omitting safeguarding assessment in a young person
  • Judgmental or rushed manner that shuts down the history
🔴 Red
Thrush treatment given blindly; no sexual history; PCB ignored; no safeguarding; judgmental manner
🟠 Amber
Discharge characterised; some sexual history; STI testing mentioned but not arranged; bleeding noted but cervix not examined; ICE partial
🟢 Green
Discharge characterised; full sexual history & risk; NAAT/STI screen offered (self-swab); PCB → examine cervix + NG12 awareness; safeguarding considered; confidentiality & non-judgment; ICE all three
2
Step 2
Triage — Emergency · Urgent (PID / Cervical / Safeguarding) · Routine
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Most discharge is managed in a single primary-care or sexual-health contact. The triage task is to pull out ectopic/sepsis, the PID that needs prompt empirical treatment, the abnormal bleeding that needs the cervix examined (and possibly an NG12 referral), and the safeguarding concern.
🔴 Emergency

Same day / 999

Immediate action
  • Possible ectopic pregnancyPain/bleeding + positive/possible pregnancy → urgent EPU/gynae
  • Severe PID / tubo-ovarian abscess / sepsisFever, severe pain, peritonism, mass → admit
  • Acute safeguarding riskExploitation/abuse with immediate risk → safeguarding emergency pathway
🟠 Urgent / Refer

Days–2 weeks

Prompt action
  • Suspicious-looking cervixSuspected cancer pathway referral (NICE NG12); persistent unexplained PCB/IMB with a normal cervix → gynae/colposcopy per local pathway
  • PID (clinical)Empirical antibiotics now; partner treatment; review
  • Safeguarding concern (non-acute)Safeguarding lead; document; refer
🟢 Routine

GP / sexual health

Primary care first-line
  • BV / candidaTreat per features; advice on recurrence
  • STI screen (asymptomatic risk / discharge)NAAT self-swab + HIV/syphilis; treat + partner notification
  • Uncomplicated chlamydiaDoxycycline; partner notification; test of cure if indicated
🎓 SCA Checkpoint — Step 2Tasks
Triage rationale
"The infection itself we can sort here, but because you've had bleeding after sex I do want to look at the cervix — and if anything looks unusual I'd refer you promptly, separately from treating any infection."
Deductions
  • Missing ectopic in a possibly pregnant woman with pain/bleeding
  • Not recognising PID needs prompt empirical treatment
  • Reassuring on PCB because of a recent normal smear
3
Step 3
Examination — When & How · Speculum · Bimanual · The Cervix
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Not every discharge needs an examination — a confident clinical picture of candida or BV in a low-risk woman can be managed on history. But abnormal bleeding, pelvic pain, treatment failure, pregnancy, or diagnostic uncertainty all require examination — and post-coital bleeding specifically requires the cervix to be visualised. Always with a chaperone and informed consent.
⚕️ When to examine
TriggerWhy
Abnormal bleeding (PCB/IMB)Visualise the cervix — exclude/identify a suspicious cervix (NG12) and cervicitis.
Pelvic pain / ?PIDBimanual for cervical motion and adnexal tenderness; assess for mass.
Treatment failure / recurrence / uncertaintyConfirm the diagnosis; take swabs.
Pregnancy / atypical featuresAssess and exclude complications.
🔬 What to do at examination
StepDetail
Inspect vulvaExcoriation (candida), ulcers (herpes/syphilis), warts, FGM.
SpeculumDischarge character; cervix appearance (friable/contact bleeding/irregular = suspicious); take swabs.
Swabs / testsVulvovaginal NAAT (chlamydia/gonorrhoea); high vaginal swab (candida/BV/trichomonas) if uncertain; endocervical culture if gonorrhoea likely (sensitivities); vaginal pH.
BimanualCervical motion tenderness, adnexal tenderness/mass → PID/ectopic.
Chaperone & consentAlways; document; respect autonomy and dignity.
🎓 SCA Checkpoint — Step 3TasksGlobal Skills
Narration that scores
"Because of the bleeding after sex I'd like to do an internal examination with a speculum to look at the cervix and take some swabs, with a chaperone present — is that okay? You can stop at any point."
Deductions
  • Not examining the cervix despite post-coital bleeding
  • No chaperone / consent not documented
  • Reflex examination when self-swab would suffice for a low-risk candida/BV picture
4
Step 4
Investigations — NAAT · Full STI Screen · Microscopy/pH · Pregnancy
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Testing turns guesswork into the right treatment and protects partners and future fertility. The core test is a vulvovaginal NAAT for chlamydia and gonorrhoea; where there is risk, offer a full STI screen including HIV and syphilis serology. BV and candida are largely clinical but swabs/pH help when uncertain or recurrent.
🧪 Tests
TestWhen / why
Vulvovaginal NAAT (self-taken)Chlamydia & gonorrhoea — recommended first-line sample in women; lowers the barrier to testing.
Full STI screenHIV and syphilis serology (± hepatitis B/C by risk) where there is risk; extra-genital (rectal/pharyngeal) swabs by exposure.
Endocervical culture (gonorrhoea)If gonorrhoea likely/positive NAAT — for antimicrobial sensitivities (resistance).
High vaginal swab / pH / microscopyIf uncertain or recurrent: BV (clue cells, pH >4.5), candida, trichomonas.
Pregnancy testIf any chance of pregnancy — alters drugs and excludes ectopic.
Glucose/HbA1cRecurrent candida — screen for diabetes.
🤝 Partner notification & follow-up

Positive STI → partner notification (often via GUM, can be anonymous) is essential to prevent reinfection and onward transmission.

Advise abstinence until both partners treated; arrange test of cure where indicated — chlamydia in pregnancy (no sooner than 3 weeks after treatment); gonorrhoea only in selected cases (BASHH 2025: not routinely needed for anogenital infection treated with ceftriaxone 1 g IM when the isolate is susceptible — needed if susceptibility unknown, pharyngeal infection, an alternative regimen, pregnancy or persistent symptoms, as advised by GUM); persistent symptoms. Retest under-25s with chlamydia for reinfection at about 3 months (NCSP; the BASHH 2026 guideline allows 2–6 months after treatment).

Offer onward referral to sexual-health services for full screening, contact tracing and complex cases.

🎓 SCA Checkpoint — Step 4Tasks
Key reasoning
"I'd like you to do a self-swab for chlamydia and gonorrhoea, and given the new relationship I'd offer a full check including HIV and syphilis blood tests — all confidential. If anything's positive we'll treat it and let partners know discreetly."
Deductions
  • Treating empirically for an STI without NAAT testing
  • Not offering HIV/syphilis in an at-risk patient
  • Forgetting partner notification / test of cure
5
Step 5
Diagnosis — BV · Candida · STIs · PID · The Cervical Red Flag
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Name the cause from the discharge character, the risk assessment and the tests — and consciously separate the infective causes from the bleeding that needs the cervix examined.
DiagnosisDiscriminating featuresSTI?
Bacterial vaginosisThin grey homogeneous discharge, fishy odour, pH >4.5, no itch; clue cells. Metronidazole.No
Vulvovaginal candidiasisThick white "curdy" discharge, vulval itch/soreness, normal pH. Azole; recurrent → maintenance + diabetes screen.No
ChlamydiaOften asymptomatic; altered discharge, dysuria, PCB/IMB; commonest STI. Doxycycline; partner notification.Yes
GonorrhoeaPurulent discharge ± dysuria; culture for sensitivities; ceftriaxone per BASHH; GUM.Yes
TrichomoniasisFrothy yellow-green discharge, odour, vulvovaginitis, "strawberry cervix". Metronidazole; partner treatment.Yes
PIDPelvic pain, deep dyspareunia, abnormal bleeding, cervical motion/adnexal tenderness. Treat empirically.Often
🚩 Cervical pathologyPCB/IMB → examine the cervix; a suspicious cervix on examination → suspected cancer pathway referral (NG12); persistent unexplained PCB/IMB with a normal cervix → gynae/colposcopy per local pathway (not an NG12 criterion); normal smear does not exclude.Suspected cancer pathway referral

🚩 The discipline — treat the infection, but examine the bleeding

The trap is to find an infective cause (BV or chlamydia), treat it, and attribute the post-coital bleeding to that — without ever looking at the cervix. Cervical cancer is repeatedly missed this way. For Aisha, the formulation is: characterise and test the discharge (likely BV ± STI given the risk), AND examine the cervix because of the post-coital bleeding — referring urgently under NG12 if it looks suspicious, independent of her recent normal smear.

🎓 SCA Checkpoint — Step 5Tasks
Explaining it plainly
"The discharge could be a couple of things, so I've tested for them and we'll treat what shows up. Separately, the bleeding after sex means I want to look at your cervix to be safe — even though your smear was normal, that's the careful thing to do."
Deductions
  • Attributing PCB to infection without examining the cervix
  • Reassuring purely on a recent normal smear
6
Step 6
Referral — GUM · Gynaecology · suspected cancer pathway referral Cervical · Safeguarding
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Much is managed in primary care or sexual-health services. Referral is for complex/recurrent STIs and contact tracing (GUM), the suspicious cervix (suspected cancer pathway), PID or ectopic concerns (gynaecology), and any safeguarding concern.
ReferralWho / whenUrgency
🟣 Suspected cervical cancerAppearance of the cervix on examination consistent with cervical cancer (mass, ulceration, irregular or friable surface, contact bleeding not explained by cervicitis) — a smear is not needed first and a previous normal result should not delay referral.Suspected cancer pathway · NICE NG12
Gynaecology / colposcopyPersistent unexplained post-coital or intermenstrual bleeding where the cervix looks normal and STI tests are negative (and contraceptive causes considered) — not itself an NG12 criterion; refer per local pathway rather than repeatedly reassuring.Per local pathway
Sexual health / GUMConfirmed/complex STI, gonorrhoea, contact tracing, full screening, recurrent infection, or patient preference.Routine / soon
GynaecologyPID not responding, tubo-ovarian abscess, or possible ectopic (urgent/EPU).Urgent by severity
SafeguardingUnder-16, coercion, exploitation, abuse, FGM concerns.Per local pathway
🔴 Acute admissionEctopic, severe PID/sepsis, tubo-ovarian abscess.Same day
🎓 SCA Checkpoint — Step 6Tasks
Stating the threshold
"If the cervix looks at all unusual when I examine it, I'll refer you on the fast-track suspected cancer pathway to gynaecology — that's standard for bleeding after sex with an abnormal-looking cervix, even with a normal smear."
Deductions
  • Not knowing/actioning the NG12 cervical pathway
  • Missing the need for GUM contact tracing in confirmed STI
7
Step 7
Management — Expectation · Goals · Self-Care · BASHH Prescribing · Drug Cards · Psychosocial · Follow-Up · Monitoring · Safety-Netting
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Management treats the specific cause, notifies and treats partners where relevant, addresses prevention and contraception, and safety-nets — while keeping any cervical red flag on its own urgent track.
7A — Address the patient's expectation first: validate → explain → negotiate
🤝
She came for thrush cream — acknowledge that, explain why the picture has changed, then offer a plan that is quick, private and hers to control
1
Validate — name the expectation and the hurry

Aisha expects a prescription for thrush and a short appointment. She has had thrush before, so her self-diagnosis is reasonable on its face, and her time pressure is real. Naming both out loud tells her you have heard her before you ask anything of her — and makes it much less likely that the rest of the plan feels like an obstacle course.

"You've had thrush before, so it makes complete sense that you thought this was the same thing — and I can see you're short of time. Let me explain why I don't think this one is thrush, and then we'll find the quickest way to sort it."
2
Explain — share the reasoning in her own terms

Three things she told you do not fit thrush: the discharge is watery rather than thick, there is a smell, and it does not itch. Together they point towards bacterial vaginosis, which needs a different medicine — thrush cream will not work. The new partner and inconsistent condoms mean a sexual-health check is sensible, and the bleeding after sex needs the cervix looked at whatever the swabs show. Keep the explanation to these three plain points; resist a lecture.

"Thrush is usually thick, white and itchy. What you're describing — watery, with a smell and no itch — sounds more like a bacterial imbalance called BV, and thrush cream won't treat that. Because there's a new partner, I'd also like to check for infections that often have no symptoms. And the bleeding after sex is the one thing I don't want to guess about."
3
Negotiate — something today, and control over the rest

She should leave with something concrete: a treatment for the likely BV if the picture fits, a self-taken swab done in the toilet next door, bloods for HIV and syphilis if she agrees, results by text, and the examination either now with a chaperone or booked at a time she chooses within the next few days. If she declines part of the plan, record that she was informed, keep the door open, and still safety-net — autonomy is respected, not punished.

"Here's what I suggest: you do a quick swab yourself, I'll treat the likely cause today, and the results come to your phone. I would really like to look at your cervix because of the bleeding — we can do that now with a chaperone, or book it for a time that suits you this week. What would work best?"
Key principle: The consultation fails in two opposite ways — handing over thrush cream (missing BV, an STI and the cervical red flag), or insisting on everything at once so she walks out with nothing. The winning move is to make the safe option the easy option: a self-swab lowers the barrier to STI testing, a same-day treatment meets her need to leave with something, and a clearly explained, time-limited plan for the examination respects her control while keeping the bleeding on track.
7B — Why treatment matters: goals tailored to this patient
Treatment goals for Aisha
The right diagnosis — BV vs candida vs trichomonas vs STI — not a guessSymptom resolution with a single, correctly chosen course Chlamydia and gonorrhoea excluded or treated; HIV and syphilis testedPartners notified and treated if positive — no reinfection Cervix visualised because of post-coital bleeding; referred if suspiciousPregnancy excluded; contraception gaps (missed pills) addressed PID and ectopic warning signs understood and safety-nettedTrust kept — she returns to this service next time rather than self-treating
Motivational language — tailored to Aisha
"You've spent three weeks with this already. Testing today means the treatment you get actually matches the cause, so you're not back here in a fortnight with the same problem and another cream that didn't work."
"Most infections we test for are simple to treat. The reason I'm keen not to miss one is that, left alone, some can quietly affect fertility later on — a quick swab now protects that."
151,163
Chlamydia diagnoses in England in 2025 — still the commonest STI (45% of new diagnoses), concentrated in 15–24-year-olds (UKHSA STI annual data, published June 2026)
63,943
Gonorrhoea diagnoses in England in 2025, with ceftriaxone-resistant strains rising — why a positive NAAT goes to GUM for culture (UKHSA STI annual data, June 2026; BASHH 2025)
pH >4.5
Vaginal pH above 4.5 supports BV (or trichomonas); candida usually leaves pH at or below 4.5 (BASHH 2012 BV; BASHH 2019 vulvovaginal candidiasis)
3 of 4
Amsel criteria for BV: thin homogeneous discharge, clue cells, pH >4.5, positive amine (whiff) test (BASHH 2012)
70–80%
Cure at 4 weeks with the recommended BV regimens — and recurrence is common afterwards, so set expectations (BASHH 2012)
≥4 / year
Episodes that define recurrent vulvovaginal candidiasis → confirm on culture, then induction + 6 months' weekly fluconazole (BASHH 2019)
72 h
Review point after starting outpatient PID treatment; no improvement → escalate (BASHH 2019 PID)
≥3 weeks
Earliest chlamydia test of cure after treatment (pregnancy) — earlier NAATs can detect non-viable DNA (BASHH)
6 months
Partner-notification look-back for women with chlamydia — all partners in the 6 months before presentation (BASHH partner-notification statement)
7C — Non-medication management: mechanism + evidence + tailored advice
Much of what prevents the next episode costs nothing and is rarely said. Self-care for BV and candida, safer sex, contraception review and screening are part of the management, not an afterthought — and each one can be tailored to what Aisha has told you.
🚿
Stop douching & perfumed products
Target: water or plain emollient externally only
Mechanism

Lactobacilli keep the vagina acidic (pH ≤4.5) by producing lactic acid; that acidity suppresses the anaerobes that cause BV. Douching, antiseptics, perfumed washes, bubble bath and vaginal deodorants strip lactobacilli and raise pH — the very conditions in which BV recurs. Irritants also cause a contact vulvitis that is easily mistaken for thrush.

Practical

Ask directly — many patients douche because they notice odour, which worsens the cycle. Advise washing the vulva with water or an unperfumed emollient and never washing inside the vagina. Explain that BV is not caused by poor hygiene; over-washing is more often the problem.

BASHH 2012 BV guideline and its BASHH patient information list douching, bubble baths, scented soaps, antiseptics and feminine washes as modifiable BV triggers
🛡️
Condoms & safer sex
Target: condoms with new partners until both tested
Mechanism

Condoms reduce transmission of chlamydia, gonorrhoea, trichomonas and HIV, and semen raises vaginal pH, so condom use is also associated with fewer BV recurrences. A new relationship is the natural moment both partners test and agree when to stop using condoms.

Practical

Frame it as routine: "many couples both get tested at the start of a relationship." Warn that clindamycin cream and clotrimazole vaginal products can damage latex condoms and diaphragms — use another method during and shortly after treatment (check product information). Free condoms are available through local sexual health services and C-Card schemes for young people.

Abstain (including oral sex) until treatment is complete and partners are treated — the commonest cause of "treatment failure" is reinfection
💊
Contraception review
Target: no pregnancy risk from missed pills; LARC offered
Mechanism

Aisha sometimes misses her pill. Missed pills plus unprotected sex create a pregnancy risk that changes drug choice (no metronidazole 2 g stat, no fluconazole, no doxycycline) and makes ectopic pregnancy part of any pain-and-bleeding differential. Metronidazole and doxycycline are not enzyme inducers and do not reduce the effectiveness of hormonal contraception.

Practical

Do a pregnancy test today. If recent missed pills and unprotected sex put her at risk, apply CoSRH missed-pill rules (emergency contraception if indicated; repeat a pregnancy test at least 3 weeks after the last unprotected sex). Offer long-acting reversible contraception — if she chooses a copper IUD, note it is associated with BV, and intrauterine contraception should not be fitted with untreated symptomatic infection or cervicitis.

CoSRH: STI test at the time of IUC fitting if at risk; delay fitting if symptomatic until tested and treated
🧪
Regular testing & self-sampling
Target: test with each new partner; retest if positive
Mechanism

Most chlamydia and much gonorrhoea is asymptomatic, so symptoms are a poor guide to infection. Testing at partner change and retesting after a positive result find reinfection before it ascends to cause PID.

Practical

Tell her about free online self-sampling kits from her local sexual health service. If chlamydia is positive, arrange a retest for reinfection at about 3 months (NCSP recommendation for under-25s; the BASHH 2026 guideline allows 2–6 months). Offer HIV and syphilis testing with each full screen; discuss PrEP only if her risk profile indicates it.

NCSP (since 2021) focuses the opportunistic offer on young women and people with a womb or ovaries aged 15–24
🚭
Smoking & alcohol
Target: no alcohol during metronidazole + 48 h after
Mechanism

Smoking is associated with BV, and stopping is one more modifiable factor for recurrence. Metronidazole product information advises avoiding alcohol during treatment and for 48 hours afterwards because of a possible disulfiram-like reaction (flushing, vomiting, palpitations) — the evidence is weak, but it remains the licensed advice.

Practical

Ask about plans for the next week — a birthday or wedding is when patients stop the course early. A vaginal gel option avoids most systemic effects if alcohol or nausea is a barrier. Offer smoking cessation support if she smokes.

Completing the course and avoiding early stopping reduces relapse
🌸
Screening & HPV
Target: attend cervical screening when invited; HPV vaccine complete
Mechanism

Cervical screening detects high-risk HPV and pre-cancer in women without symptoms; it is not a diagnostic test for someone with symptoms. That is why post-coital bleeding needs the cervix examined even after a normal screening result — screening and symptom assessment are separate pathways.

Practical

Reinforce that her normal screening result is good news for the future, but does not answer today's question. Check HPV vaccination status (routine in the UK schools programme). Explain that the cervical examination today is about the bleeding, not a repeat smear.

NICE NG12: a previous normal screening result should not delay referral of a suspicious-looking cervix
7D — Prescribing guide: BASHH regimens by cause, and the plan for Aisha today
Treatment follows the cause and the named BASHH guideline for that cause. Doses below are those stated in BASHH guidance (BV 2012, trichomonas 2021, chlamydia 2018 update / 2026, gonorrhoea 2025, PID 2019, vulvovaginal candidiasis 2019) and match the site's protocols; always check doses in the SPC and your local formulary before prescribing. Pregnancy and breastfeeding change several choices.
CauseFirst-line (BASHH)Pregnancy / breastfeedingPartnersFollow-up
Bacterial vaginosis
BASHH 2012
Treat if symptomatic: metronidazole 400 mg BD for 5–7 days, or 2 g single dose; or metronidazole 0.75% gel 5 g nightly × 5; or clindamycin 2% cream 5 g nightly × 7.Treat symptomatic BV; use 400 mg BD 5–7 days or a vaginal option — avoid the 2 g dose. Do not screen asymptomatic pregnant women (UK NSC).Not routinely treated (BASHH 2012).No test of cure if symptoms settle; swab if persistent or recurrent.
Vulvovaginal candidiasis
BASHH 2019
Fluconazole 150 mg oral stat, or clotrimazole 500 mg pessary stat (± clotrimazole 1% cream externally).Topical only — clotrimazole pessary for up to 7 nights; avoid oral fluconazole.Not routinely treated.Recurrent (≥4/yr): culture to confirm, then fluconazole 150 mg every 72 h × 3, then 150 mg weekly for 6 months; HbA1c.
Trichomoniasis
BASHH 2021
Metronidazole 400–500 mg BD for 7 days.Same 7-day regimen; avoid 2 g stat; inform the antenatal team.Treat current partners simultaneously, whatever their result.Abstain until both treated; full STI screen; test of cure if symptoms persist.
Chlamydia
BASHH 2018 → 2026
Doxycycline 100 mg BD for 7 days.Azithromycin 1 g then 500 mg daily for 2 days (preferred), or 1 g single dose, erythromycin or amoxicillin (BASHH 2026); confirm with local sexual health.Look back 6 months (all women); treat contacts without waiting for results.Test of cure in pregnancy ≥3 weeks after treatment; retest under-25s at ~3 months (BASHH 2026: 2–6 months).
Gonorrhoea
BASHH 2025
Refer to GUM: culture first, then ceftriaxone 1 g IM single dose (monotherapy).Ceftriaxone 1 g IM remains first-line; no quinolones; liaise with maternity team.Look back 3 months (2 weeks for symptomatic male urethral infection).Test of cure only where indicated (≥2 weeks); abstain until 7 days after all treated.
PID
BASHH 2019
Ceftriaxone 1 g IM stat, then doxycycline 100 mg BD + metronidazole 400 mg BD for 14 days — start the same day.PID in pregnancy → admit; always exclude ectopic first.Partners from the 6 months before symptom onset.Review at 72 hours; again at 2–4 weeks.
Today — before prescribing anything
  • Pregnancy test — she misses pills; this decides the regimen
  • Vaginal pH on narrow-range paper from the lateral wall: >4.5 supports BV or trichomonas, ≤4.5 favours candida
  • Self-taken vulvovaginal NAAT for chlamydia and gonorrhoea (± trichomonas NAAT, given the odour)
  • HIV and syphilis serology offered; hepatitis B/C by risk
  • Ask about pelvic pain, deep dyspareunia, fever — any PID feature changes the plan
Likely BV, not pregnant, no PID features
  • Oral metronidazole 400 mg BD — a 7-day course sits within the BASHH BV range and matches the trichomonas regimen while that result is pending
  • Or a vaginal gel/cream if she prefers (clindamycin cream: condom warning)
  • Do not give thrush treatment for a non-itchy, odorous, pH >4.5 discharge
  • Treat chlamydia/gonorrhoea on the result, not blindly — unless PID features, mucopurulent cervicitis or a known positive contact
No alcohol during metronidazole and for 48 hours after
The bleeding — a separate track
  • Speculum examination with chaperone — today if she agrees, otherwise booked within days
  • Cervix looks consistent with cancer → suspected cancer pathway referral (NICE NG12), whatever the screening history
  • Cervicitis / contact bleeding → swabs, treat per result or presumptively per sexual health advice
  • Ectropion (common on the combined pill) or normal cervix → reassure if bleeding settles; persistent unexplained PCB with negative tests → gynaecology/colposcopy per local pathway
7D (cont.) — Quick table: treat by cause, and beyond the prescription
💊 Specific treatment
CauseTreatment
Bacterial vaginosisTreat if symptomatic: metronidazole 400 mg BD 5–7 days or 2 g stat (not 2 g in pregnancy/breastfeeding), or metronidazole 0.75% gel 5 nights, or clindamycin 2% cream 7 nights (BASHH 2012); avoid douching; partners not routinely treated; not an STI.
CandidaAzole: oral fluconazole 150 mg stat or clotrimazole 500 mg pessary stat (± 1% cream externally). Pregnancy: topical only — clotrimazole pessary for up to 7 nights; no oral fluconazole. Recurrent (≥4/yr, confirmed) → fluconazole induction (150 mg every 72 h × 3) then 150 mg weekly for 6 months (BASHH 2019); HbA1c.
ChlamydiaDoxycycline 100mg BD 7 days (azithromycin in pregnancy); partner notification; abstain until treated; test of cure if pregnant/persistent.
GonorrhoeaRefer to sexual health: culture before treatment, ceftriaxone 1 g IM single dose (BASHH 2025 — monotherapy, no routine azithromycin); partner notification; test of cure where indicated (not routine for susceptible anogenital infection).
TrichomonasMetronidazole 400–500 mg BD for 7 days (BASHH 2021; same regimen in pregnancy — no 2 g stat); treat current partner(s) simultaneously regardless of their result; full STI screen.
PIDEmpirical antibiotics the same day — BASHH 2019 outpatient regimen: ceftriaxone 1 g IM stat, then doxycycline 100 mg BD + metronidazole 400 mg BD for 14 days; pregnancy test first; partner notification; review at 72 hours; safety-net.
🛡️ Beyond the prescription
ElementDetail
Partner notificationVia GUM (can be anonymous); abstain until both treated; prevents reinfection.
PreventionCondoms; STI risk-reduction advice; HPV vaccination status; consider PrEP discussion/referral by risk.
ContraceptionAddress need (LARC, emergency contraception); pregnancy intentions.
Safety-net"Return urgently if you develop pelvic pain, fever, or heavier bleeding"; PID and ectopic warning.
Follow-upResults, test of cure where indicated, the cervical referral if made, recurrence review.
7E — Drug reference cards: vaginal discharge and STI treatments
No interactive medication chooser exists for this topic — the choice is driven by the cause, pregnancy and the named BASHH guideline (table in 7D). Doses are those stated by BASHH; check the SPC and your local formulary.
Metronidazole (oral / vaginal gel)
Metronidazole 400 mg tablets · metronidazole 0.75% vaginal gel
✓ First-line for BV (oral or vaginal gel) and trichomonas (oral only — vaginal gel is not effective for TV)
First-lineBV: 400 mg BD 5–7 d or 2 g stat · TV: 400–500 mg BD 7 d
✓ Prefer when
Symptomatic BV — oral 400 mg BD for 5–7 days, 2 g single dose, or 0.75% gel 5 g nightly for 5 nights (BASHH 2012)
Trichomoniasis — 400–500 mg BD for 7 days; vaginal gel is not adequate for TV (BASHH 2021)
Part of the 14-day outpatient PID regimen with ceftriaxone and doxycycline (BASHH 2019)
✗ Avoid / caution
2 g single dose in pregnancy and breastfeeding — use the multi-day regimen
Alcohol during and for 48 h after (licensed advice); warfarin (enhanced anticoagulant effect — check INR per SPC); disulfiram; lithium — check SPC interactions
⚠ Side effects
Metallic taste, nausea (take with or after food), GI upset; rarely peripheral neuropathy with prolonged courses
🔬 Monitor
Symptom response only; no test of cure for BV if symptoms settle. Persistent symptoms → swab (Gram stain, TV NAAT, candida), check adherence and reinfection.
💬 Counselling

"Take one tablet twice a day with food for the full course, even if things settle quickly. It can leave a metallic taste. Please don't drink any alcohol while you're taking it and for two days afterwards — it can make you feel very unwell."

SCA: state the alcohol warning, avoid the 2 g dose if pregnancy is possible, and explain that BV is not an STI and partners are not routinely treated — unlike trichomonas, where the partner must be treated.

Clindamycin 2% vaginal cream
Clindamycin 2% cream, 5 g applicator
✓ Equal first-line option for BV
Alternative route5 g at night for 7 nights (BASHH 2012)
✓ Prefer when
Patient prefers a vaginal treatment, cannot tolerate oral metronidazole, or wishes to avoid the alcohol restriction
Switching route after a confirmed BV relapse on oral treatment
✗ Avoid / caution
Relying on latex condoms or a diaphragm — the oil-based cream weakens latex; use another method during treatment and for the period stated in product information
History of antibiotic-associated colitis — check SPC
⚠ Side effects
Local irritation; vulvovaginal candidiasis after treatment
🔬 Monitor
Symptom response; review if persistent or recurrent. Thrush symptoms afterwards → treat as candida.
💬 Counselling

"Use one applicator full at bedtime for seven nights. It can weaken condoms and diaphragms, so they won't protect you reliably while you're using it — we'll talk about what else to use."

SCA: offering a choice of route is shared decision-making; forgetting the condom warning is a safety omission.

Clotrimazole (pessary / cream)
Clotrimazole 500 mg pessary · clotrimazole 1% or 2% cream
✓ First-line topical azole; the choice in pregnancy
First-line500 mg pessary stat (BASHH 2019)
✓ Prefer when
Acute vulvovaginal candidiasis — itch, soreness, thick white discharge, pH ≤4.5
Pregnancy or possible pregnancy — topical azole for up to 7 nights; oral fluconazole is avoided
Add external cream for vulval symptoms
✗ Avoid / caution
Odorous, non-itchy discharge with pH >4.5 — this is not candida; do not treat as thrush
May damage latex condoms and diaphragms (product information: for at least 5 days after treatment); in pregnancy insert the pessary by hand rather than with the applicator
⚠ Side effects
Local burning or irritation; rarely hypersensitivity
🔬 Monitor
Should improve within days. No response → swab for culture and speciation; reconsider BV, trichomonas, dermatitis, lichen sclerosus.
💬 Counselling

"Insert the pessary high into the vagina at bedtime. The cream is for the outside if you're itchy or sore. If you're pregnant, use your finger rather than the applicator. If it isn't clearly better in a week, come back so we can take a swab rather than repeat the treatment."

SCA: recognising that repeated self-treated "thrush" often is not thrush is a key reasoning point; the cream is right only when the features fit.

Fluconazole (oral)
Fluconazole 150 mg capsule (also available from pharmacies)
✓ First-line oral azole (not in pregnancy)
First-line150 mg stat · RVVC: 150 mg q72h × 3, then weekly × 6 months (BASHH 2019)
✓ Prefer when
Acute candidiasis in a non-pregnant woman who prefers a tablet
Recurrent VVC (≥4 episodes a year, confirmed on culture as C. albicans) — induction then 6-month weekly maintenance
✗ Avoid / caution
Pregnancy, possible pregnancy and breastfeeding — use topical treatment (BASHH 2019)
Interactions — QT-prolonging drugs, warfarin, some statins, sulfonylureas; hepatic impairment — check SPC
Non-albicans species (e.g. C. glabrata) may not respond — refer rather than repeat
⚠ Side effects
GI upset, headache, rash; rarely hepatotoxicity
🔬 Monitor
On maintenance: breakthrough episodes, pregnancy status and contraception; HbA1c at the start of RVVC work-up; liver function if prolonged use per SPC.
💬 Counselling

"This is a single capsule. If you're on the weekly course, please use reliable contraception and tell us straight away if you might be pregnant — we'd switch you to a cream or pessary."

SCA: "Could you be pregnant?" before fluconazole is a safety question that scores. For recurrence, confirm the diagnosis and check HbA1c before committing to six months of treatment.

Doxycycline
Doxycycline 100 mg capsules
✓ First-line for chlamydia
First-line100 mg BD × 7 days (BASHH); × 14 days in PID regimen
✓ Prefer when
Uncomplicated urogenital, rectal or pharyngeal chlamydia; epidemiological contacts
With ceftriaxone and metronidazole for PID (14 days)
✗ Avoid / caution
Pregnancy — use the azithromycin regimen; breastfeeding — azithromycin, or a short doxycycline course where alternatives are unsuitable (BASHH 2026)
Separate from antacids, iron, calcium and zinc; photosensitivity
⚠ Side effects
Oesophageal irritation/ulceration, nausea, photosensitive rash
🔬 Monitor
Adherence; no routine test of cure for uncomplicated, fully adhered treatment; retest under-25s for reinfection at ~3 months (BASHH 2026: 2–6 months).
💬 Counselling

"Take it twice a day for a week with a full glass of water, sitting or standing, not just before bed. Use sun protection. No sex — including oral sex — until you've finished the course and your partner has been treated too. It doesn't affect your pill."

SCA: doxycycline replaced single-dose azithromycin as first-line in 2018 (more effective, particularly for rectal infection). Pair the prescription with partner notification and abstinence advice every time.

Azithromycin (pregnancy / doxycycline unsuitable)
Azithromycin 500 mg tablets
Alternative for chlamydia
Alternative1 g, then 500 mg daily for 2 days in pregnancy (BASHH 2026)
✓ Prefer when
Chlamydia in pregnancy, breastfeeding, or tetracycline allergy/intolerance
✗ Avoid / caution
QT prolongation risk and interacting drugs; hepatic impairment — check SPC
Not routine co-treatment for gonorrhoea any more (BASHH 2025)
⚠ Side effects
GI upset, diarrhoea
🔬 Monitor
Pregnancy: test of cure no sooner than 3 weeks after completing treatment; retest later in pregnancy if at ongoing risk.
💬 Counselling

"This is a single dose. Because you're pregnant, we'll check the infection has gone with a repeat test in about three to four weeks. Your partner needs treating before you have sex again."

SCA: knowing the pregnancy switch and the test of cure is the difference between a pass and a strong pass.

Ceftriaxone (usually given by GUM)
Ceftriaxone 1 g intramuscular injection
✓ Gonorrhoea and PID
Specialist-led / PID1 g IM single dose (BASHH 2025 / 2019)
✓ Prefer when
Gonorrhoea — after culture, as monotherapy (BASHH 2025)
PID — stat dose, followed by 14 days of doxycycline + metronidazole (BASHH 2019); do not give the oral drugs without it
✗ Avoid / caution
Severe immediate hypersensitivity to beta-lactams — specialist alternative regimen
Suspected treatment failure or Asia-Pacific acquisition → urgent GUM for culture and UKHSA reporting
⚠ Side effects
Injection-site pain; GI upset; hypersensitivity
🔬 Monitor
Test of cure where indicated (≥2 weeks for gonorrhoea); PID review at 72 hours.
💬 Counselling

"The sexual health clinic will take a sample to check which antibiotics work before giving you an injection. It's important to go — tablets alone are no longer reliable for gonorrhoea."

SCA: route positive gonorrhoea to GUM for culture, treatment, partner notification and test of cure rather than prescribing tablets.

7F — Psychosocial impact: relationships, work, identity and trust
🤝
A "simple" discharge that touches relationships, fertility worries and self-image
For many patients the hardest part of this consultation is not the treatment but what the diagnosis seems to say about them — cleanliness, faithfulness, their partner, their future fertility. The GP who treats the infection but leaves those meanings unexamined sends the patient home to worry, argue, or avoid the next test.
💔
Telling a partner

A positive STI result can feel like an accusation. Offer the options for partner notification — telling the partner herself, the clinic contacting partners anonymously, or a joint approach — and be clear that timing of infection usually cannot be determined. If there is any concern about abuse, partner notification is done by the service, not by the patient.

"You don't have to have this conversation alone. The sexual health team can contact your partner without giving your name."
🧼
Shame and "being dirty"

BV and thrush are commonly misunderstood as hygiene problems, which drives more washing and more recurrence. Explicitly de-stigmatise: BV is a change in the balance of normal bacteria, candida is a normal inhabitant that overgrows, and neither reflects cleanliness.

"This isn't about being clean or not — washing more can actually make it worse. It's just the balance of the normal bacteria that has shifted."
🍼
Fertility fears

Mentioning fertility can motivate testing but can also frighten. Put it in proportion: a treated chlamydia infection found early is very unlikely to cause problems; the risk lies in untreated or repeated infection and PID. Offer that perspective proactively if a result is positive.

"Finding it now and treating it is exactly what protects your fertility — it's infections that are missed for a long time that cause problems."
💼
Work and practicalities

This rarely needs time off work or a fit note. The practical barriers are appointments, results and the examination: offer text results, early or late slots, and direct booking with sexual health. Driving: there are no DVLA implications for these conditions or for the standard treatments.

"You won't need any time off for this. Let's make the follow-up fit around work — results by text, and an appointment time that suits you."
🔐
Confidentiality and records

Worries about who can see the record — parents on the same practice list, a partner with access to her phone or NHS App — are common and legitimate. Explain what goes in the record, that sexual health clinics keep separate confidential records, and agree safe contact details.

"If you'd prefer, the sexual health clinic can do the tests, and their records are kept separately from your GP notes."
🔁
Recurrence and frustration

Recurrent BV or thrush erodes quality of life, sex and confidence, and patients often cycle through pharmacy treatments. Validate the frustration, confirm the diagnosis properly, and offer a plan (triggers, route switch, suppression with specialist advice) rather than another identical prescription.

"If this keeps coming back, it deserves a proper plan — not just another box of the same thing."
7G — Follow-up schedule
1
Today — test, treat the likely cause, plan the examination

Pregnancy test; pH; self-taken vulvovaginal NAAT (chlamydia/gonorrhoea ± trichomonas); HIV and syphilis serology offered. Treat likely BV if not pregnant and no PID features. Speculum examination with chaperone now or booked within days. Safeguarding and coercion questions documented. Agree how she will receive results. Contraception: missed pills, emergency contraception if indicated.

Cervix must be seenSelf-swab + bloods
2
Within about a week — results and the examination

Check results are back and acknowledged; positive chlamydia → doxycycline (or azithromycin regimen if pregnant) + partner notification; positive gonorrhoea or trichomonas → sexual health for treatment and partner management. Examination completed: suspicious cervix → suspected cancer pathway referral (NG12); cervicitis treated; ectropion explained. If she did not attend for the examination, contact her — a missed examination for post-coital bleeding is a safety gap, not just a DNA.

Results acted onDNA → recall
3
72 hours — only if PID treatment was started

Review response to ceftriaxone + doxycycline + metronidazole (BASHH 2019). No improvement → reconsider diagnosis, consider admission and imaging. Check adherence to the 14-day course and that partners are being notified.

No improvement = escalate
4
2–6 weeks — symptoms and test of cure where needed

BV: no test of cure if symptoms have settled; persistent symptoms → HVS Gram stain, TV NAAT, candida, look for a retained tampon or foreign body. Chlamydia in pregnancy: test of cure no sooner than 3 weeks after treatment. Gonorrhoea: test of cure where GUM advises. Post-coital bleeding: if it continues with a normal-looking cervix and negative tests → gynaecology/colposcopy referral per local pathway.

ToC only where indicatedPersistent PCB → refer
5
About 3 months — retest if chlamydia was positive

Under-25s who test positive for chlamydia are offered a retest for reinfection at around 3 months (NCSP; BASHH 2026 allows 2–6 months, and uptake is best when offered early). Offer a full screen at any new partner. Review recurrence of BV or thrush: triggers, route switch, and specialist input for suppression if frequent.

Reinfection retestRecurrence plan
7H — Monitoring: results, test of cure and recurrence

Memory rule — test of cure vs retest

Test of cure asks "did the treatment work?" — needed for chlamydia in pregnancy (≥3 weeks), gonorrhoea where GUM advises (≥2 weeks), and persistent symptoms. Retest asks "has she been reinfected?" — around 3 months after a positive chlamydia test in under-25s. BV and uncomplicated thrush need neither if symptoms settle. Post-coital bleeding is monitored until it has stopped or been referred.

WhatWhoWhenAction threshold
NAAT resultsEveryone testedAs soon as reported (usually days)Positive → treat, partner notification, abstinence advice; unacknowledged results actively recalled
Pregnancy testAny chance of pregnancyToday; repeat ≥3 weeks after last unprotected sexPositive + pain/bleeding → same-day early pregnancy assessment; positive → adjust all drug choices
Chlamydia test of curePregnant; poor adherence; persistent symptomsNo sooner than 3 weeks after treatmentPositive → consider reinfection vs failure; discuss with sexual health
Gonorrhoea test of cureSusceptibility unknown/reduced, pharyngeal, alternative regimen, pregnancy, persistent symptoms≥2 weeks after treatment (BASHH 2025)Positive → urgent GUM; culture; report suspected resistance
Chlamydia reinfection retestUnder-25s positive for chlamydiaAround 3 months (BASHH 2026: 2–6 months)Positive → retreat and revisit partner notification
PID responseOn PID treatment72 hours; 2–4 weeksNo improvement → reassess, consider admission/imaging
BV / candida symptomsTreated for BV or thrushIf persistent after treatment or recurringPersistent → swab (Gram stain, culture/speciation, TV NAAT); ≥4 candida episodes/yr → confirm and induction–maintenance + HbA1c
Post-coital bleedingAishaExamination within days; review at 4–6 weeksSuspicious cervix → NG12 referral; persistent, cervix normal, tests negative → gynae/colposcopy
SafeguardingUnder-18s; any coercion concernEvery contactUnder 13, or exploitation/abuse indicators → safeguarding referral; no concern → document assessment
7I — Safety-netting: exact phrases + medico-legal rationale

⚠ Three scenario-specific phrases — use these verbatim

🔴 Same day — ectopic, severe PID, sepsis
"If you get pain low down in your tummy that is getting worse, pain in your shoulder tip, feel faint, have a fever or feel very unwell — especially if there's any chance you're pregnant — don't wait for an appointment. Call 111 or come in the same day, and if you collapse or the pain is severe, call 999."
Ectopic pregnancy and severe PID/tubo-ovarian abscess can evolve over hours. Missed pills plus a new partner make pregnancy possible, so the ectopic safety-net is not theoretical for Aisha.
🟠 Urgent — bleeding and PID symptoms
"Please come back within a day or two if the bleeding after sex happens again, if you get bleeding between periods, or if you develop pain deep inside during sex — and please don't cancel the appointment to look at your cervix, even if the discharge clears up."
Treating the discharge often resolves the symptom that brought her in, which is exactly when the examination for post-coital bleeding gets dropped. The phrase decouples the two.
🟢 Routine — results and persistence
"You'll get your results by text within about a week. If you haven't heard, please contact us — don't assume no news is good news. If the discharge hasn't settled by the end of the tablets, come back so we can take a swab rather than just repeating treatment."
Results that are never acknowledged are a recognised source of harm; making the patient a partner in closing the loop, alongside practice recall, adds a second safety layer.
TodayPregnancy test; self-swab NAAT; HIV/syphilis; treat likely BV; examination now or booked
~1 weekResults acted on; partners notified; cervix examined; NG12 referral if suspicious
~3 monthsChlamydia retest if positive (under-25); recurrence plan; full screen at partner change
💬 Key phrases for this consultation
💭 Reframing "thrush"
"Thrush is usually thick, white and itchy. Watery with a smell and no itch sounds more like BV — and thrush cream won't treat that."
😟 Naming the STI worry
"Lots of people in a new relationship wonder about infections — it's very common and nothing to be embarrassed about. Is that something that's been on your mind?"
🎯 Meeting the expectation
"You'll leave today with treatment for the most likely cause, and a test you can do yourself for the rest."
🛑 The smear is not the answer
"Your screening test being normal is really good news. It checks for changes before symptoms appear — but now that there's been bleeding, the right thing is to look at the cervix directly."
🤝 Partner notification
"If anything comes back positive, the sexual health team can let partners know without using your name. It's routine and it stops the infection coming back to you."
📋 Safety-net
"Worsening tummy pain, fever, feeling faint or shoulder-tip pain — especially if you could be pregnant — means same-day help, not waiting for results."
🔴🟠🟢 RAG — management
Tasks
🟢
Pregnancy test; pH; self-swab NAAT + HIV/syphilis; BV treated with correct regimen and alcohol warning; no reflex thrush cream; cervix examined or examination booked with rationale; NG12 threshold stated; partner notification and abstinence; retest/ToC rules known; safeguarding and coercion assessed
🟠
Correct treatment but no pregnancy test; STI testing arranged without HIV/syphilis; examination "suggested" but not booked; partner notification mentioned without a route; test of cure applied to everything or nothing
🔴
Thrush treatment given; no testing; post-coital bleeding not examined or reassured on the smear; fluconazole or 2 g metronidazole with pregnancy not excluded; no PID/ectopic safety-net
Relating to Others
🟢
Expectation named and reframed; confidentiality and its limits explained; self-swab offered; examination consented with control retained; partner notification framed as blame-free; results route agreed; leaves feeling helped
🟠
Explains reasons but in jargon; checks consent but little sense of control; confidentiality asserted without its limits; STI worry not explored
🔴
Judgmental questions; pressure to be examined; lecture on condoms; patient leaves with nothing or disengages
🚫 Danger zones in management
✗
Thrush cream for an odorous, non-itchy discharge→ The features point to BV (or trichomonas). Check pH and treat the cause; candida usually has normal pH and itch.
✗
Post-coital bleeding attributed to the infection→ Examine the cervix. A cervix consistent with cancer → NG12 suspected cancer pathway, regardless of screening history.
✗
Fluconazole, doxycycline or metronidazole 2 g without a pregnancy check→ She misses pills. Test first; use topical azole, azithromycin regimen or metronidazole 400 mg BD if pregnant.
✗
PID treated as "just BV" or with doxycycline alone→ Pelvic pain + tenderness = PID until proven otherwise: ceftriaxone 1 g IM + 14 days doxycycline + metronidazole (BASHH 2019), pregnancy test, 72-hour review.
✗
Oral tablets for gonorrhoea in general practice→ Refer to GUM for culture and ceftriaxone 1 g IM (BASHH 2025); resistance is rising.
✗
Treating the patient but not the partner→ Chlamydia, gonorrhoea and trichomonas need partner notification and abstinence advice; BV and candida do not need routine partner treatment.
✗
Missing safeguarding in a young person→ Every under-18 needs a proportionate exploitation assessment; under-13 = safeguarding referral every time (Sexual Offences Act 2003). FGM disclosed by, or visually identified in, an under-18 must be reported to the police within one month (FGM mandatory reporting duty, England and Wales).
✗
Repeated empirical treatment for "recurrent" discharge→ Confirm the diagnosis (Gram stain, culture/speciation, TV NAAT), look for a foreign body or retained tampon, check HbA1c for recurrent candida, and consider lichen sclerosus or dermatitis.
🎓 SCA Checkpoint — Step 7TasksRelating to OthersGlobal Skills
A plan that scores
"Here's the plan: a self-swab and a full sexual-health check today, treatment for whatever shows up, partners notified discreetly if needed, a look at your cervix because of the bleeding, and a safety-net for pelvic pain or fever. Everything stays confidential."
Deductions
  • Treating without testing; no partner notification
  • Ignoring the cervical red flag; no safety-net for PID/ectopic
  • Missing contraception/prevention opportunity
Vaginal Discharge & STI — SCA Consultation Scorecard
BASHH · Sexual history · NAAT/STI screen · Partner notification · Safeguarding · Cervical red flag (NG12)
0/ 33 pts
🌐
Global Skills
Structure, language, responsiveness
0/7
✓
Tasks
Clinical reasoning, diagnosis, management
0/15
🤝
Relating to Others
Communication, rapport, shared decisions
0/11
RAG Self-Assessment
🔴 Red
Thrush treatment given blindly; no sexual history/testing; PCB ignored; no safeguarding; no partner notification; judgmental
🟠 Amber
Discharge characterised; some history; testing mentioned not arranged; bleeding noted but cervix not examined; ICE partial
🟢 Green
Confidential non-judgmental history; NAAT/STI screen; PCB → examine cervix + NG12; safeguarding; partner notification; treat by cause; ICE all three; safety-net
011172533
Fail
Borderline
Pass
Strong pass
📋
Complete the checklist to see your score and feedback
"Hi — I think I've got thrush again. Could I just get some treatment for it? I'm in a bit of a rush, to be honest."
Who you are

Aisha Rahman, 24, office worker. Three weeks of increased vaginal discharge — but it's "different from my usual thrush": more watery and there's a smell. You assumed it's thrush and want treatment so you can get on with your day. You feel a bit awkward talking about it. You've had a new partner for about two months and you haven't always used condoms. If asked sensitively, you'll admit you had some light bleeding after sex once last week, which you found a bit embarrassing and didn't want to bring up. Your first cervical screening test, three months ago, was normal. You're well otherwise — no fever, no bad pain. You're hesitant about being examined and would rather just take a tablet/cream and go.

Hidden concerns (reveal if explored)

STI worry (main, unspoken): deep down you're worried it might be an infection from the new partner, but you're embarrassed to say so. If the doctor is non-judgmental and confidential, you open up.

The bleeding: you didn't want to mention it; if asked directly and gently, you'll admit it. If the doctor explains why they want to look, you'll agree to an exam.

Privacy: you're worried about confidentiality. Reassurance helps a lot.

Clinical details if asked
  • Discharge: watery, greyish, with an odour; no real itch; "not like my usual thrush"
  • One episode of light post-coital bleeding last week; no bleeding between periods otherwise
  • New partner ~2 months; inconsistent condom use; male partner; no other recent partners
  • No fever, no severe pelvic pain; mild discomfort only
  • Last menstrual period ~2 weeks ago; on the pill (sometimes misses one); could you be pregnant? unlikely but not certain
  • First cervical screening test three months ago: normal (HPV negative); up to date with HPV vaccine; no past STIs that you know of
  • You feel safe in the relationship; partner is a similar age
Reactions at key moments
  • On being asked about sex: initially a bit guarded; opens up if the doctor is warm and non-judgmental.
  • On the self-swab: relieved you can do it yourself; happy to.
  • On examination for the bleeding: hesitant, but agree if it's explained and you're reassured you're in control.
  • Challenge line: "Can't you just give me the cream? I don't really want all these tests and an examination."
"Honestly, I just wanted some thrush treatment — do we really need to do swabs and an examination? It's a bit embarrassing."

Resolution: Aisha is satisfied if the GP: (1) creates a confidential, non-judgmental space and takes a sexual history; (2) recognises the picture isn't simple thrush and offers a self-taken NAAT + full STI screen, explaining why; (3) gently elicits and acts on the post-coital bleeding — examining the cervix and explaining the NG12 pathway if it looks suspicious, not reassuring on the normal smear alone; (4) handles partner notification and prevention sensitively; (5) safety-nets for PID/ectopic. She disengages if she feels judged, rushed, or is simply handed thrush cream with the bleeding ignored.

🏥
Clinic Quick Reference
Vaginal Discharge & STI — Clinical Decision Framework
BASHH · BV · candida · STI · PID · Cervical red flag (NG12)
▼expand
🚦 1 — Triage first
Vaginal discharge
▼
🔴 Same-day
  • Possible ectopic (pain/bleeding + ?pregnant)
  • Severe PID / sepsis / TOA
  • Acute safeguarding risk
Admit / urgent
🟠 Urgent
  • Suspicious cervix → NG12; persistent unexplained PCB/IMB → gynae/colposcopy
  • PID (clinical) → empirical Rx
  • Safeguarding concern
Suspected cancer pathway referral / treat
🟢 Routine
  • BV / candida
  • STI screen & treat
GP / GUM
🔍 2 — Diagnose & treat
Not an STI

BV: thin grey, fishy, pH>4.5 → metronidazole. Candida: white, itchy, normal pH → azole; recurrent → maintenance + diabetes screen.

STI / PID

NAAT self-swab + HIV/syphilis by risk. Chlamydia → doxycycline; gonorrhoea → ceftriaxone (culture); trichomonas → metronidazole. PID → empirical antibiotics, low threshold. Partner notification + test of cure. PCB/suspicious cervix → examine + NG12.

🎓
SCA Quick Reference
Vaginal Discharge & STI — Consultation Playbook
Confidentiality · test don't guess · examine the bleeding · safeguard
▼expand
🎯 The three pivots that pass this case
1 · The red flag
Post-coital/intermenstrual bleeding → examine the cervix. A suspicious cervix → NG12 suspected cancer pathway referral, even with a normal smear.
2 · Test, don't guess
"Different from usual thrush" + new partner → sexual history + vulvovaginal NAAT + full STI screen, not reflex thrush cream.
3 · The wraparound
Partner notification, safeguarding, confidentiality, prevention/contraception — and a PID/ectopic safety-net.
⛔ Don't reflex-prescribe thrush treatment without a sexual history · Don't attribute post-coital bleeding to infection without examining the cervix · Don't reassure on a normal smear alone · Don't forget partner notification, safeguarding and confidentiality · Have a low threshold to treat PID and exclude ectopic
Reviewed: July 2026 · citations verified against the primary sources listed