Mental Health · Full case

Eating Disorders

NICE NG69MEEDSCOFF
ED
Eating Disorders · Clinical Reasoning Framework v2
GP & SCA · NICE NG69 · MEED · SCOFF · AN · BN · BED · Refeeding · Fluoxetine 60mg · Lisdexamfetamine · Early referral
BMI <13 = MEED emergencyBMI <13 kg/m² in adults = life-threatening anorexia nervosa; hospital admission required regardless of patient wishes. BMI 13–15: very high risk; same-day specialist eating disorder assessment or medical admission. Rapid weight loss (>1 kg/week) also triggers MEED assessment regardless of absolute BMI. MEED = Management of Really Sick Patients with Anorexia Nervosa (RCPsych).
Fluoxetine 60mg for BN (not 20mg)Bulimia nervosa: fluoxetine 60mg OD is NICE NG69 first-line pharmacotherapy — NOT the standard 20mg depression dose. 60mg reduces binge-purge frequency by ~50%. Combined with guided self-help (CBT-BN). Anorexia nervosa: SSRIs are NOT recommended (not effective in underweight patients; risk of QTc prolongation on already vulnerable cardiac substrate). Nutrition must precede medication in AN.
SCOFF ≥2 = refer (no confirmed diagnosis needed)SCOFF questionnaire: ≥2 positive answers = screen positive for eating disorder. NICE NG69: GPs should NOT wait for confirmed diagnosis before referring to eating disorder service. Early referral improves prognosis. Referral to specialist eating disorder service (not general CMHT). Delay in referral is a common and significant error in eating disorder management.
Eating disorders: highest psychiatric mortalityEating disorders have the highest mortality of any psychiatric disorder (anorexia nervosa: 5–10% long-term mortality; deaths from cardiac arrhythmia, renal failure, electrolyte disturbances, suicide). Males represent approximately 1 in 4 presentations but are frequently unrecognised and experience greater diagnostic delay. Do not apply weight-based criteria alone — history and behaviour drive diagnosis.
Refeeding syndrome: monitor electrolytesRefeeding syndrome: dangerous fall in phosphate, potassium, magnesium during nutritional rehabilitation of severely malnourished patients. Insulin release during refeeding drives intracellular shift of electrolytes → hypophosphataemia; hypokalaemia; hypomagnesaemia → cardiac failure; seizures; respiratory failure; death. Monitor phosphate, potassium, magnesium at 48–72h and daily during inpatient refeeding. Specialist eating disorder unit guidance required.
Lisdexamfetamine: licensed for BEDLisdexamfetamine (Vyvanse): NICE TA607 (2019) — licensed for moderate-to-severe binge eating disorder (≥3 binge eating episodes/week for ≥3 months). Specialist initiation. Controlled drug (Schedule 2). 30mg OD titrated to 50–70mg OD. CI: cardiovascular disease; hypertension; hyperthyroidism; history of substance misuse. Only licensed pharmacotherapy specifically for BED.
MEED: HR <40; BP <80/50; K+ <2.5MEED physical emergency indicators requiring same-day hospital referral: resting HR <40 bpm; BP <80/50 mmHg; blood glucose <3 mmol/L; K+ <2.5 mmol/L (any electrolyte severely deranged); QTc >450ms (women) / >430ms (men); rapid weight loss; BMI <13; unable to stand from chair without arms (severe muscle weakness). Any single criterion = medical emergency.
AN: no effective medication; nutrition firstAnorexia nervosa: there is no NICE-approved first-line medication. SSRIs are NOT effective in underweight patients and carry QTc risks. Olanzapine: low evidence; off-label; reduces anxiety and may support weight gain at very low doses; not routinely recommended (NICE NG69). Nutritional rehabilitation (via eating disorder service) is the primary treatment. Never offer medication as the only or primary treatment for AN.
📋 Clinical Stem — Eating Disorders
A 19-year-old first-year university student attending at her flatmate’s urging, with a BMI of 16.2, 8 kg weight loss over 4 months, three months of amenorrhoea, and daily exercise of 2–3 hours, who says “I just want to be healthy”
Emma Carter, 19, attends with her flatmate Priya who has come to the door and waits in reception. Emma is a first-year psychology student who has been at university for 4 months. She presents reluctantly — Priya made the appointment because she has noticed Emma skipping meals, exercising for 2–3 hours daily, and looking visibly thinner. Emma denies there is a problem: “I just eat a bit less and exercise more — I’m being healthy.” On measurement: weight 47 kg; height 1.70 m; BMI 16.2. She has lost approximately 8 kg since arriving at university. She confirms her periods stopped 3 months ago (“I’m less stressed without them”). SCOFF questionnaire administered: she scores 3/5. She shows no lanugo hair on examination, no Russell’s sign. She has mild bradycardia (HR 52 bpm) but her BP is within normal limits sitting. Electrolytes are pending. She is cooperative but minimises and deflects.
This stem tests six clinical skills: identifying restricting-type anorexia nervosa from the clinical picture while navigating a patient who minimises and deflects; performing and interpreting the SCOFF questionnaire; applying MEED risk stratification (BMI 16.2 = moderate risk; HR 52 bpm borderline; no immediate MEED emergency but urgent referral required); understanding why NICE NG69 mandates early referral without waiting for confirmed diagnosis; approaching the control function of the eating disorder without framing the consultation primarily as “you need to eat more”; and discussing referral to an eating disorder service (not CMHT) in a way that Emma can accept.
Scenario A — MEED emergency 22-year-old with known anorexia nervosa attending after 3-week inpatient admission, now re-presenting with BMI 11.8, HR 36 bpm, BP 74/48 mmHg, severe hypokalaemia (K+ 2.1 mmol/L) on bloods taken the previous day. MEED emergency: this is a same-day hospital admission situation. 999 or urgent ambulance. IV access; cardiac monitoring; potassium replacement; electrolyte correction under specialist supervision. Do NOT try to manage this in GP. Mental Health Act: if patient refuses hospital admission and capacity is intact, consider whether compulsory treatment is appropriate (Section 3 MHA can cover medical treatment of anorexia nervosa where failure to treat would result in serious deterioration).
Scenario B — Bulimia nervosa 24-year-old administrative assistant, normal BMI (22.4), presents with acid reflux and dental erosion. During SCOFF screening (positive: 2/5), discloses binge-purge cycle 4–5 times per week for the past 18 months. Russell’s sign on examination. AUDIT score low. Electrolytes: K+ 3.1 mmol/L (mildly low from purging). Management: eating disorder service referral; guided self-help (CBT-BN) first-line; fluoxetine 60mg OD (not 20mg) if psychological therapy not available or patient preference; dental referral; monitoring K+ and electrolytes; safety-netting about oesophageal complications.
Scenario C — Binge eating disorder 41-year-old with obesity (BMI 36), type 2 diabetes, and depression. Discloses eating large amounts rapidly in secret at least 3 times per week for over 3 months, with significant distress but no compensatory behaviours. BED diagnosis. Management: guided self-help (CBT-based); sertraline if comorbid depression; lisdexamfetamine 30mg OD (NICE TA607) for moderate-to-severe BED if guided self-help insufficient — controlled drug; specialist initiation recommended; weight management programme; address metabolic comorbidities.
Scenario D — Male eating disorder 17-year-old male (referred by school nurse), BMI 17.1, excessive gym attendance (2–3 hours daily), restricting carbohydrates severely (“I’m cutting for sport”). Males: 1 in 4 eating disorder presentations; often present later due to stigma; more likely to present with a performance or sport narrative rather than body image concerns; same SCOFF questionnaire; same MEED risk criteria; ARFID and muscle dysmorphia more prevalent in males. Earlier recognition essential. Safeguarding: 17 years old; parental involvement appropriate; school involvement.
Scenario E — ARFID (Avoidant/Restrictive Food Intake Disorder) 14-year-old with severe restriction of food types (eats only 5-6 foods; refuses any new texture); BMI 16.8; no body image disturbance; no fear of weight gain. ARFID: distinguished from AN by absence of body image distortion — avoidance is based on sensory features, fear of choking, or past negative experiences, not weight or shape concerns. Often comorbid with ASD or anxiety. Treatment: specialist dietitian + psychologist; sensory food exposure; not the same treatment pathway as AN or BN. NICE NG69 covers ARFID; specialist eating disorder service referral appropriate.
Key variables to adapt for BMI and rate of weight loss (MEED criteria; determines urgency of referral); eating disorder subtype (AN restricting vs binge-purge; BN; BED; ARFID — different treatments); male vs female (males 1 in 4; different presenting narrative; same clinical criteria); age (under 18: paediatric eating disorder service; Child and Adolescent Mental Health Service; parental involvement; safeguarding); severity of physical compromise (electrolytes; ECG QTc; bradycardia; hypotension; muscle strength; glucose); patient’s motivation and stage of change (denial vs contemplation; never impose weight gain as the frame — discuss values and function).
Steps:
1
Step 1
History Taking — SCOFF Screen · Eating Behaviours · Control Function · ICE · Safeguarding
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The eating disorder history has a different structure from most consultations: the patient often does not recognise the problem as a problem, or actively conceals it. Emma says she wants to be healthy — the GP’s task is not to argue with this framing, but to gently widen it: “what does being healthy mean to you?” and “how do you feel in your body right now?” The SCOFF questionnaire is the validated screening tool; BMI must be measured (not estimated); and the history must include the function the restrictive behaviour serves — control; identity; coping mechanism — which is what treatment must ultimately address.
🎓 SCA opener — acknowledge the reluctance before any clinical questions
"I’m glad you came in. I understand this was Priya’s suggestion rather than your own — I want to start by saying that this is your consultation, not Priya’s. I’m not here to tell you what to do or what to eat. What I’d like to do is understand how things are going for you at university and have a chat about your health — including some things around eating and exercise that it sounds like might have changed recently. Would that be OK?"
In SCA: opening with an explicit statement that this is Emma’s consultation — not her flatmate’s — and that the GP is not going to tell her what to eat immediately removes the greatest barrier to engagement (fear of being forced to change). It also establishes that the GP is interested in Emma as a whole person, not just her weight. Candidates who launch straight into “I can see from your BMI that you are underweight” immediately lose the patient’s trust and receive poor Relating to Others scores.
1A — SCOFF screen and eating behaviour history
QuestionWhy it mattersChanges what?
🏲 OPEN QUESTION"How have you been finding things at university generally — the social side, the academic side, and how you’ve been looking after yourself?" The open question about university life rather than eating is diagnostically important for two reasons. First, it signals that the GP is interested in Emma as a whole person in context — not just her body weight — which reduces defensiveness. Second, it allows Emma to reveal the psychosocial stressors (transition to university; loss of school friendships; academic pressure; homesickness; loneliness) that are the triggers for the restrictive eating behaviour. The shift from school to university is a well-documented high-risk period for eating disorder onset: loss of familiar structure; new social environment requiring identity renegotiation; academic performance anxiety; independence from parents who previously monitored eating. Understanding what has changed in Emma’s life since coming to university reveals the function the eating restriction is serving (control; a sense of mastery when other things feel out of control).In SCA: the open contextual question before SCOFF screening scores Global Skills for structured data gathering in the context of a sensitive topic. It also gives the GP information about psychosocial drivers that informs the formulation. Context (transition stress; loneliness; academic pressure) reveals function of eating restrictionTrigger identification shapes psychological treatment approach
SCOFF questionnaire — all 5 questions"I am going to ask you five questions that I ask a lot of young people — they’re not pointed at you specifically. Just answer yes or no to each. [S] Do you ever make yourself sick because you feel uncomfortably full? [C] Do you worry that you have lost control over how much you eat? [O] Have you recently lost more than one stone — about 6 kilos — in a three-month period? [F] Do you believe yourself to be fat when others say you are too thin? [F] Would you say that food dominates your life?"SCOFF (Sick; Control; One stone; Fat; Food) is the validated five-item eating disorder screen used in primary care. Scoring: each yes = 1 point; ≥2 = positive screen for possible eating disorder. Sensitivity approximately 100% for anorexia and bulimia in validated studies; high sensitivity for BED. NICE NG69: positive SCOFF screen triggers referral to eating disorder service — without waiting for diagnostic confirmation. Emma scores 3/5 (No/Yes/Yes/Yes/No = score 3): positive. Framing as a routine question administered to many patients reduces stigma and defensiveness. The ‘F’ question (do you believe yourself fat when others say too thin) is particularly diagnostically specific for anorexia nervosa (ego-syntonic body image distortion).SCOFF ≥2: refer to eating disorder service (NICE NG69). SCOFF 0–1: eating disorder less likely; monitor and reassess. All 5 SCOFF items positive: severe concern; priority referral; concurrent MEED physical risk assessment.SCOFF ≥2 = positive screen; eating disorder service referral
Current eating pattern — without using the word “diet”"Can you talk me through a typical day of eating — from waking up to going to bed? Just a normal day recently."Asking for a typical day’s eating avoids the ambiguity of “how much do you eat?” which generates evasive summary answers. The day-by-day narrative reveals: total caloric intake; meal skipping; specific food avoidance patterns; rituals around eating (cutting food very small; eating alone; avoiding social meals); evidence of control (knowing exact calorie counts; rigid rules); binge-purge patterns if present. Emma’s pattern: black coffee for breakfast; an apple or nothing for lunch; a small dinner alone in her room (avoiding the communal kitchen). She has elaborate rules: no carbohydrates after noon; no eating after 6pm; checking calorie counts on everything. This level of food-rule structure is characteristic of AN restricting type. Compensatory behaviours absent (no purging; no laxatives) — but excessive exercise (2–3 hours daily) is a compensatory behaviour variant.Restricting only: AN restricting type; eating disorder service. Binge-purge pattern (AN or BN): assess electrolytes urgently (K+ depletion). Excessive exercise (2–3h/day): compensatory exercise is a BN and AN feature; note and document.Restricting type vs binge-purge type; excessive exercise as compensatory behaviour
Exercise pattern and relationship with exercise"You mentioned exercising — can you tell me more about what that looks like? How long, how often, and how do you feel if you miss a session?"Compulsive exercise in eating disorders is a compensatory behaviour equivalent to purging: it is used to “earn” food or “undo” eating; it generates intense anxiety if missed; it continues despite injury or illness. Emma’s 2–3 hour daily exercise routine has these features: she runs every morning before lectures; she does not miss sessions even when unwell or exhausted; she becomes highly anxious and irritable if circumstances prevent exercise. This feature is clinically important for physical risk (cardiac stress during exercise in a patient with bradycardia and electrolyte derangement) and for treatment (exercise restriction is a therapeutic target and often the most distressing component of treatment for patients like Emma). Document as a MEED physical risk: vigorous exercise with bradycardia = cardiac arrhythmia risk.Compulsive exercise with anxiety on missing sessions: clinically significant compensatory behaviour; elevated cardiac risk; address in treatment plan. Moderate exercise for enjoyment: lower urgency.Compulsive exercise = compensatory behaviour; cardiac risk in bradycardic patient
Weight history and body image"When you look in the mirror or think about your body — how do you feel about it? And can you remember when you last felt comfortable in your body?"Body image disturbance is a core diagnostic feature of anorexia nervosa: persistent distorted perception of body size (feeling fat despite being severely underweight; or seeing a fat version of the body when looking in the mirror). This is distinguished from low self-esteem about weight (present in BN and BED) by being egosyntonic — the patient genuinely perceives their body incorrectly, not just feels bad about an accurate perception. Emma may say she still feels too big — this is the SCOFF “F” response — which is characteristic of AN. Weight history: what was Emma’s pre-university weight? Rate of loss (8 kg over 4 months = 2 kg/month = 0.5 kg/week — significant but not yet MEED rapid weight loss criterion >1 kg/week). Lowest ever weight? Previous episodes of restrictive eating?Distorted body image (feels fat when objectively underweight): AN body image criterion; severity indicator. Accurate body image with drive for thinness: other phenotypes. Rate of weight loss: >1 kg/week = MEED criterion; document rate.Body image distortion: characteristic of AN; core diagnostic feature
1B — Red flags: MEED physical emergency criteria
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Red Flags — MEED physical emergency criteria: any single criterion = same-day hospital

Red flagWhy dangerousAction
Resting HR <40 bpm; any cardiac arrhythmiaMalnutrition causes cardiac atrophy (the heart is a muscle), bradycardia, and electrolyte disturbances (hypokalaemia; hypophosphataemia; hypomagnesaemia) that prolong QTc and precipitate life-threatening arrhythmias (ventricular tachycardia; ventricular fibrillation). Sudden cardiac death is the leading cause of mortality in AN. Emma’s HR of 52 bpm is borderline — HR <40 would trigger immediate hospital admission. ECG essential at every assessment.ECG immediately; electrolytes; same-day eating disorder team or medical admission; no vigorous exercise
Blood glucose <3 mmol/LStarvation hypoglycaemia: impaired hepatic gluconeogenesis from malnutrition; glycogen stores depleted. Life-threatening if severe. In AN: hypoglycaemia may occur without the usual adrenergic symptoms (attenuated response). Can cause sudden loss of consciousness without warning. Immediate glucose replacement required; hospital admission for monitoring.999 if unconscious; oral glucose if conscious; IV glucose + thiamine (Pabrinex) if malnourished; hospital admission
Severe hypokalaemia (K+ <2.5 mmol/L)Hypokalaemia from purging (BN) or from starvation (AN — renal potassium wasting): extends QTc; precipitates fatal arrhythmias; causes muscle weakness, ileus, rhabdomyolysis. Mild hypokalaemia (3.0–3.5): oral potassium replacement. Severe (<2.5): IV replacement under cardiac monitoring. Never give IV potassium outside hospital without continuous ECG.Same-day hospital: IV potassium under cardiac monitoring; ECG; MEED pathway
BMI <13 kg/m² (adults); or rapid weight loss >1 kg/weekBMI <13: critical malnutrition; multi-organ failure risk; cardiac atrophy; immunosuppression; bone marrow suppression. Even if the patient appears clinically stable at this weight, there is minimal physiological reserve — any intercurrent illness can be rapidly fatal. Rapid weight loss (>1 kg/week even from a higher BMI): trajectory suggests critical deterioration ahead; same-day eating disorder assessment required regardless of absolute BMI.Same-day eating disorder service or medical admission; MEED pathway; consider compulsory treatment (MHA) if capacity impaired or refusal with life-threatening risk
Severe muscle weakness — unable to stand from seated position without using armsProfound muscle wasting: reliable bedside indicator of very severe malnutrition. The “squat test” or “stand from chair” test — if the patient cannot rise from a standard chair without using their arms — indicates severe proximal myopathy from protein depletion. Carries very high risk of falls, aspiration, inability to protect airway. Inpatient admission required.Inpatient admission; MEED pathway; supervised nutritional rehabilitation; physiotherapy assessment
QTc >450 ms (women) / >430 ms (men) on ECGQTc prolongation in AN: from hypokalaemia, hypophosphataemia, hypomagnesaemia, and direct cardiac effects of malnutrition. Risk of Torsades de Pointes (polymorphic VT) → ventricular fibrillation → sudden cardiac death. SSRI antidepressants further prolong QTc — this is why SSRIs are CONTRAINDICATED in underweight AN patients. Any medication that prolongs QTc must be avoided or used only with cardiology input.Same-day cardiology review; hospital admission; cardiac monitoring; stop any QTc-prolonging medication including SSRIs; electrolyte correction under monitoring
🛡️

Safeguarding and Risk Assessment

Eating disorders carry significant mortality risk and may require consideration of the Mental Health Act. In severe anorexia nervosa where the patient lacks capacity to make decisions about food intake (and some who appear to have capacity may not: food-related decisions may be impaired by the illness itself), or where refusal of treatment carries a real risk of death, Section 3 MHA or Section 2 MHA assessment may be warranted. The GP’s role is to assess risk, initiate specialist eating disorder referral urgently, and document the clinical and safeguarding reasoning.
🕑 Physical Risk to Life
  • AN has the highest mortality of any psychiatric disorder: 5–10% long-term mortality from cardiac causes, renal failure, infections, and suicide
  • Physical risk assessment at every consultation: BMI; HR; BP (sitting and standing); electrolytes; glucose; ECG
  • MEED criteria met → same-day hospital referral regardless of patient wishes; GP has a duty of care
  • If Emma had BMI <13, HR <40, or severe electrolyte disturbance: medical admission today, discussion with eating disorder team, and potentially MHA assessment
👨‍🏫 Under-18s — Parental Involvement and CAMHS
  • If the patient is under 18: Child and Adolescent Mental Health Services (CAMHS) eating disorder pathway; parental involvement usually appropriate; Fraser competence assessment if refusing parental involvement
  • Young people under 18 with AN refusing food: Section 3 MHA assessment if at serious risk
  • Emma is 19: adult eating disorder service; parental involvement only with her consent
  • Priya (flatmate) has initiated contact — with Emma’s agreement, Priya may be a supportive contact for care co-ordination
😤 Suicide and Self-Harm Risk
  • Suicide is a significant cause of death in AN (second most common cause after cardiac); PHQ-9 and direct suicide risk assessment at every consultation
  • Emma: first year of university; significant social and academic adjustment; social isolation (eating alone); amenorrhoea (can worsen mood); loss of school social network — multiple risk factors
  • Direct enquiry: "Sometimes when people are going through a difficult time, they have thoughts of harming themselves — have you had any thoughts like that?" — normalising framing; always ask in this population
  • If active suicidal ideation: crisis team; crisis plan; safety planning alongside eating disorder referral
📰 Mental Health Act Considerations
  • Section 2 MHA: assessment; 28 days; for diagnostic assessment in severe AN where patient refuses voluntary admission
  • Section 3 MHA: treatment; 6 months; can authorise nasogastric feeding in patients with capacity (precedent: B v Croydon); and in those without capacity
  • The eating disorder itself may impair capacity around food-related decisions even if the patient appears logical in other domains; specialist psychiatric assessment required
  • Emma: not currently at a severity threshold for MHA; but document risk assessment and escalation plan
GP safeguarding actions in eating disorders: MEED physical assessment at every GP contact; if MEED criteria met: same-day eating disorder team alert and hospital referral with clear documentation; suicide risk assessment with PHQ-9; if patient under 18: Children and Young People eating disorder service (referral to be seen within 1 week for urgent, 4 weeks for routine, per NICE NG69 timelines); involve eating disorder specialist in complex capacity assessments; document all clinical and safeguarding reasoning carefully.
1C — PMH · Medication · Social history
🥐 Medical history and physical comorbidities
FactorWhy it mattersImpact
Amenorrhoea (3 months)Amenorrhoea in AN: hypothalamic suppression from low body weight and energy deficit. Not in DSM-5 criteria (removed 2013) but clinically significant marker of severity. When periods stop from AN: bone density loss begins (hypo-oestrogenaemia); fertility is affected; hormonal dysregulation. Requires formal pregnancy test (rule out pregnancy as cause); then DEXA bone density scan if amenorrhoea persists beyond 6 months. Periods typically return with weight restoration. Do NOT prescribe OCP merely to restore periods — does not protect bone density in this context (NICE NG69).Pregnancy test (rule out). DEXA if amenorrhoea >6 months. Calcium + vitamin D supplementation. Weight restoration is the primary treatment for amenorrhoea in AN — not hormonal treatment.
Bone density riskAN causes the most severe bone density loss of any condition in young people — worse than post-menopausal osteoporosis in terms of rate. Mechanism: low oestrogen (amenorrhoea); low IGF-1; high cortisol; inadequate nutritional calcium. Risk is proportional to duration of illness and lowest BMI reached. Fracture risk increased even in young patients — stress fractures common. Prevention: weight restoration (most important); calcium 1000–1500 mg/day + vitamin D; bisphosphonates not recommended in young patients (teratogenic).Calcium 1000–1500 mg/day + vitamin D 800–1000 IU/day. DEXA scan if BMI <17.5 for >1 year. Weight restoration is the most effective bone density intervention. Do NOT use bisphosphonates in reproductive-age women.
Previous eating disorder or dieting historyPrior eating disorder episodes carry a higher risk of chronicity. Dieting history, family comments about weight, or exposure to thin-ideal media (social media) are risk factors. Comorbid OCD (obsessive features about food rules) and anxiety disorder are common in AN. Comorbid depression (secondary to starvation) is very common. Trauma history (abuse, bullying about weight) may be present. Previous contact with eating disorder services may inform current referral pathway and treatment approach.Prior ED episode: higher risk of chronicity; specialist eating disorder team to be informed of history. Comorbid OCD or anxiety: address in psychological treatment. Previous trauma: trauma-informed care needed.
Medications — QTc interactionsIn patients with AN (potential bradycardia and electrolyte disturbances that already prolong QTc), any medication that further prolongs QTc is potentially dangerous. QTc-prolonging drugs: most antidepressants (SSRIs, especially citalopram and escitalopram); antipsychotics (quetiapine, haloperidol); antiemetics (domperidone, metoclopramide); antibiotics (ciprofloxacin, clarithromycin); antihistamines (some). In underweight AN: avoid SSRIs unless BMI is approaching normal range and QTc confirmed normal. Fluoxetine has least QTc effect among SSRIs — if SSRI essential (comorbid depression), fluoxetine preferable.Review all medications for QTc prolongation before prescribing. SSRIs not effective in underweight AN (and potentially harmful). If QTc >450ms: stop QTc-prolonging drugs; cardiology input. Fluoxetine: safest SSRI if essential for comorbid severe depression in AN approaching normal weight.
🏠 Social history and psychosocial context
FactorWhy it mattersImpact
University transition stressThe transition from school to university is a well-recognised precipitant for eating disorder onset: loss of structured environment (mealtimes at home); new social environment requiring renegotiation of identity; academic pressure; homesickness; first experience of independent food procurement. Emma’s eating restriction began within the first weeks of university — strongly suggests a stress-triggered onset. The control hypothesis: when the new environment feels overwhelming and out of control, controlling food intake is a coping mechanism that feels manageable. Understanding this function does NOT mean validating or enabling the restriction — but it does mean addressing the underlying stressor in psychological treatment.Psychosocial formulation: university stress = trigger; food restriction = coping mechanism. Psychological treatment must address the underlying stress; not just eating behaviours. Eating disorder service: structured CBT-AN or MANTRA (Maudsley Anorexia Nervosa Treatment for Adults) addresses this.
Social isolation and mealtime avoidanceEmma eats alone in her room; avoids the communal kitchen (avoids others seeing what and how little she eats; avoids social pressure to eat more); has declined social invitations involving food (pizza; halls dinner). Social isolation from eating disorder is both a consequence and a perpetuator — it removes the corrective social experience of normal eating in company and deepens the illness-driven food rules. The eating disorder is also replacing social connection: food-control may provide a sense of identity and purpose when social belonging feels difficult. Note: social isolation also increases depression and suicide risk.Social isolation: safety concern; depression risk; assess PHQ-9. Eating disorder treatment must include social eating rehabilitation. Explore support network: Priya; family (does Emma’s family know?).
Academic performance and perfectionismHigh academic achievement and perfectionism are characteristic personality traits in AN. Emma (psychology student; likely high attainment) may be using exercise performance and dietary restriction as a parallel achievement domain when academic achievement feels uncertain or insufficient. The eating disorder often becomes an “achievement” in itself: being the thinnest, the most disciplined, eating the least. This framing is important for CBT-AN: the eating disorder as a valued achievement must be addressed directly in therapy, not bypassed.Perfectionism and academic pressure: themes for CBT-AN; MANTRA. Explore academic standing: is Emma passing? Academic withdrawal is an early functional decline indicator. University welfare officer referral alongside eating disorder service.
Family knowledge and supportDoes Emma’s family know about her weight loss? AN frequently involves active concealment from family: wearing loose clothing; claiming to have eaten; avoiding family mealtimes when visiting home. Family involvement is a critical component of eating disorder treatment, particularly in younger patients. NICE NG69: family-based treatment (FBT) is strongly recommended for adolescents with AN and may be offered to adults. However, Emma is 19 (adult eating disorder services): family involvement is with her consent. Priya’s involvement (with Emma’s agreement) as a welfare contact is appropriate.Family knowledge: if family unaware and Emma is willing, encourage disclosure with support. Family-based treatment: available for under-18s and can be offered with consent to adults. Priya’s involvement: with Emma’s consent, as welfare contact.
1D — ICE
💡 Ideas
"When you say you want to be healthy — what does that look like for you? What does healthy feel like in your body? And when you exercise for 2 to 3 hours — what is that doing for you?"
Emma’s illness model is that she is pursuing health, not harming herself. The “health” framing is ego-syntonic — the eating disorder has attached itself to a socially valued goal (health; fitness; self-discipline). Exploring what healthy means to Emma often reveals the underlying values: control; predictability; achievement; not being judged. Understanding Emma’s model is essential before any intervention — a GP who immediately contradicts it ("this is not healthy, this is an eating disorder") will close the conversation. A GP who explores it curiously ("that is interesting — what does feeling healthy feel like to you?") may get beneath the health narrative.
😟 Concerns
"I want to ask — is there anything about this appointment that you were worried about? Anything you were afraid I might say or do?"
Emma’s central fear is almost certainly: that the GP will tell her to eat more (removing her control); force her to stop exercising; refer her to a programme where she will be made to gain weight; or inform her parents. The GP who names these fears explicitly and addresses them directly — "I am not going to take control away from you; what I want is for you to understand what your body is telling me" — establishes a therapeutic relationship in which Emma can begin to think about her situation differently. Naming the fear is not collusion with the eating disorder — it is recognising the barrier to engagement.
🎯 Expectations
"What would need to be different — either in your body or your life — for today to feel like it had been worth coming? Is there anything you’d want me to help with?"
Emma may not expect anything from this appointment (she came reluctantly). Exploring what she would want — even if she initially says “nothing” — reveals her values and what she cares about that is not yet dominated by the eating disorder. She may say she wants more energy to study; she wants her periods to come back eventually; she wants to stop feeling so cold all the time. These are the entry points for motivational work: “the things you want — the energy, the periods, feeling warm — are all connected to giving your body a bit more of what it needs. I can show you the evidence for that."
1E — Psychosocial context: the control function of eating restriction
🧑‍🏫 Understanding what the eating restriction is doing for Emma before asking her to give it up

For Emma, restricting food and exercising compulsively is not irrational behaviour — it is a coping mechanism that is working (in the short term) for specific problems: she feels out of control in a new environment; she feels anxious, lonely, and academically uncertain; the one thing she can control is her body. The eating disorder has also become an identity — perhaps the strongest sense of self she has right now. Any therapeutic approach that simply confronts the eating behaviour without addressing its function will fail. The GP’s role is to build the case for change in terms Emma values — not to remove her coping mechanism without offering an alternative.

🌟 Control and Mastery

The transition to university has removed Emma’s previous sources of control (familiar school routine; family meals; known friendship group; academic track record). Food restriction and exercise provide a domain of certainty and self-mastery in a life that feels unstable. Asking Emma to eat more is asking her to give up her primary coping mechanism. The GP who acknowledges this explicitly — without endorsing the restriction — takes the eating disorder seriously as a response to a real problem.

"It sounds like eating less and exercising is one of the things that gives you a sense of control when other things feel uncertain. I understand why that feels important. Can I ask — are there other areas of your life where you feel that same sense of being on top of things?"
👥 Social Isolation and Identity

Emma eats alone; avoids communal meals; has declined social invitations involving food. The eating disorder has replaced social belonging as a source of identity. This is both a clinical sign and a treatment barrier: the illness is filling the role that normal social connection should fill. Eating disorder recovery requires rebuilding the social connection that was lost — and the eating restriction itself prevents this (social meals are avoided). This vicious cycle must be named in treatment.

"You mentioned you tend to eat on your own in your room. How is that working for you socially? Do you miss having meals with other people? Or does that feel like more of a relief?"
🎓 Academic Pressure and Perfectionism

Emma is a first-year psychology student — the academic transition from school (where she knew how to succeed) to university (where the academic bar is higher and the feedback less immediate) creates a competence uncertainty that is threatening to a perfectionist. Dietary control and exercise performance become parallel achievement domains where success is immediately measurable and predictable. This “achievement” function is explicitly addressed in MANTRA (Maudsley Anorexia Nervosa Treatment for Adults).

"How is the psychology course going? Is it what you expected? I ask because for some people, when things feel very demanding academically, finding something else where they feel successful — like exercise — can feel very important."
🏡 Home and Family Context

Does Emma’s family know? How were mealtimes at home? Was food or body weight commented on at home? Family dynamics and early messages about food and body image are risk factors for eating disorder development. A critical family culture around food or weight; a parent or sibling with an eating disorder; a history of comments about Emma’s weight — all inform the formulation. Family-based treatment is effective for adolescent AN and may be offered with consent to adults; the GP who explores the family context may identify whether family involvement in treatment would be helpful or counterproductive.

"When you were at home, what were mealtimes like? Was food something that was talked about a lot? And does your family know about how things have changed since you started university?"
🎓 SCA Checkpoint — Step 1TasksRelating to OthersGlobal Skills
Key phrases that score
"I’m going to ask you five questions — I ask these to a lot of young people who come in. There’s no right or wrong answer. [SCOFF ×5] Based on what you told me, I want to share some thoughts with you — and I want to be really clear: I am not here to take anything away from you or tell you what to eat. I want to understand what is going on and make sure your body is safe."
"When you say you want to be healthy — I believe you. Can I ask what healthy feels like? When did you last feel genuinely healthy in your body?" [Listen carefully — this reveals what Emma values that the eating disorder is eroding]
"I want to ask about something that sometimes happens for people when they are going through a big change — do you find that controlling what you eat gives you a sense of being on top of things? I am asking because I want to understand, not because I am judging it."
Deductions
  • Leading immediately with weight or BMI before ICE — "your BMI is 16.2 which is underweight" as the opening gambit closes the conversation with an ambivalent patient
  • Arguing with the “I’m being healthy” illness model — increases resistance
  • Not performing SCOFF questionnaire — validated screening tool required per NICE NG69
  • Not asking about suicide risk — AN has significant suicide mortality; PHQ-9 required
🔴 Red
No SCOFF; opened with weight/BMI confrontation; argued with illness model; no ICE; no suicide risk assessment; did not explore control function; told Emma to “just eat more”
🟠 Amber
SCOFF administered; illness model acknowledged; MEED physical risk partially assessed; ICE attempted; control function not explored; suicide risk not directly assessed; referral mentioned but not explained
🟩 Green
Reluctance acknowledged; SCOFF ×5 administered and scored; illness model explored without confrontation; MEED physical assessment (BMI; HR; BP); control function of restriction explored empathetically; suicide risk assessed (PHQ-9); ICE all three; eating disorder service referral discussed with Emma’s involvement; family/Priya contact with consent; clear safety net
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Step 2
Triage — MEED Emergency · Urgent Referral · Routine Eating Disorder Service
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Eating disorder triage is physical-risk-led: MEED criteria determine whether the patient needs hospital admission today, urgent specialist eating disorder assessment within one week, or routine referral within four weeks. Emma (BMI 16.2; HR 52; no severe electrolyte disturbance) is in the urgent category: not an immediate emergency but requires eating disorder service contact within one week.
🔴 MEED Emergency

Hospital Admission Today

Same-day medical or eating disorder unit
  • BMI <13 in adults; or BMI 13–15 with rapid deteriorationLife-threatening malnutrition; multi-organ failure risk; cardiac atrophy
  • Resting HR <40 bpm; or QTc >450ms (F) / >430ms (M)Fatal arrhythmia risk; sudden cardiac death; continuous cardiac monitoring required
  • Severe electrolyte disturbance: K+ <2.5; glucose <3 mmol/LArrhythmia; seizure; loss of consciousness; IV replacement under monitoring
  • Unable to rise from chair without arms (proximal myopathy)Severe protein depletion; falls risk; aspiration risk; inpatient rehabilitation
  • BP <80/50 mmHg; syncope; collapseCardiovascular compromise; autonomic failure from malnutrition
🟠 Urgent — Emma

Eating Disorder Service within 1 Week

NICE NG69: urgent pathway
  • BMI 15–17.5; SCOFF ≥2; amenorrhoea; significant weight lossEmma’s current category; eating disorder service urgent referral; weekly physical monitoring in GP
  • Bradycardia (HR 40–50); mild electrolyte disturbancePhysical monitoring (ECG; electrolytes) alongside urgent eating disorder referral
🟩 Routine Eating Disorder Referral

4-week Pathway

NICE NG69: routine pathway
  • SCOFF ≥2; BMI >17.5; no physical risk indicators; OSFED or early AN/BNRoutine eating disorder service referral (4 weeks); GP monthly physical monitoring
  • BN or BED; normal weight range; no acute physical riskEating disorder service; guided self-help; fluoxetine 60mg (BN); lisdexamfetamine (BED) if criteria met
🎓 SCA Checkpoint — Step 2Tasks
Triage for Emma
"I want to be honest with you about where I think things are. Your weight and your heart rate tell me you are in a category where I need to refer you to a specialist eating disorder team — not in six months, but urgently. That means within the next week. This is not because there is a crisis today — but because the team needs to see you before things get to that point."
Deductions
  • Not referring until “confirmed diagnosis” — NICE NG69 mandates referral on SCOFF ≥2 without diagnostic confirmation; delay worsens prognosis significantly
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Step 3
Examination — MEED Physical Assessment · BMI · HR · BP · Muscle Strength
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The eating disorder physical examination is the MEED risk assessment: it determines the urgency of intervention. Every finding is clinically actionable.
ExaminationWhat to findFinding changes managementChanges?
BMI (measured weight and height — NOT estimated)
Must weigh patient; do not accept self-report
BMI must be measured at every eating disorder review — patients frequently underreport weight. Calculate BMI = weight (kg) / height (m)². Emma: 47 kg / (1.70)² = 16.27 — moderately low (17.5 = lower limit of normal for adults). Rate of change matters: serial BMI measurement at every review (document date, weight, BMI). Weekly or fortnightly measurement during active management. BMI 13–15: MEED very high risk; BMI <13: life-threatening — hospital admission. BMI 15–17.5 (Emma): significant eating disorder; urgent referral required. Weighing also provides an opportunity to acknowledge the emotion attached to the number with Emma — this is not a neutral measurement.BMI <13: same-day hospital. BMI 13–15: urgent eating disorder assessment or medical admission. BMI 15–17.5 (Emma): urgent referral (1 week). BMI >17.5: may have other eating disorder (BN; BED; ARFID); consider referral based on SCOFF and symptoms.YES — BMI threshold determines urgency and setting of care
Pulse (resting; sitting; count for 60 seconds)Bradycardia is a cardinal MEED indicator. Mechanism: cardiac atrophy from malnutrition (cardiomyopathy); reduced stroke volume; vagal overdrive. Resting HR <40: emergency. HR 40–50 (Emma has HR 52): significant bradycardia; urgent referral; ECG essential; vigorous exercise contraindicated (arrhythmia risk during exercise in setting of bradycardia and electrolyte disturbance). The risk is not just the resting bradycardia — it is the arrhythmia risk during Emma’s 2–3 hour exercise sessions while bradycardic and potentially hypokalaemic. She must be told to avoid vigorous exercise until cleared by the eating disorder team and electrolytes are normal.HR <40: MEED emergency; hospital admission; cardiac monitoring. HR 40–50: urgent referral; ECG; no vigorous exercise. HR 50–60 (Emma): borderline; ECG; urgent eating disorder referral; specific advice about exercise restriction during this period.YES — HR determines MEED urgency; exercise safety advice
Blood pressure — sitting AND standing
Postural hypotension: drop >20 mmHg systolic on standing
Postural hypotension (sitting-to-standing drop >20 mmHg systolic, or >10 mmHg diastolic): reflects dehydration, autonomic failure, or severe malnutrition. Risk: syncope and falls on standing — particularly dangerous in a patient exercising 2–3 hours daily. BP <80/50 mmHg: MEED emergency. Postural hypotension without absolute low BP: significant; address fluid and electrolyte status; restrict vigorous exercise. Emma’s BP within normal limits sitting — check standing. If she feels light-headed on standing: postural hypotension; important in the exercise context.BP <80/50: MEED emergency; hospital. Postural drop >20 mmHg: significant; fluid/electrolyte assessment; restrict vigorous exercise; eating disorder urgent referral.YES — postural hypotension changes exercise advice and urgency
Muscle strength — squat test / stand from chairAsk patient to sit in standard chair; rise to standing without using hands or arms on the chair. Inability = proximal myopathy from severe protein depletion. MEED indicator. Also relevant for Emma’s exercise: severe proximal myopathy plus vigorous exercise = musculoskeletal injury risk; cardiac stress risk. Grip strength (using GP’s hand) is an informal screen — reduced grip strength in a young adult suggests significant muscle wasting. Temporal wasting (loss of temporal muscle bulk) visible on inspection — indicates chronicity and severity.Unable to stand without arms: MEED emergency; hospital admission; physiotherapy assessment. Mild weakness but can stand: document; restrict vigorous exercise; eating disorder urgent referral.YES — proximal myopathy is a MEED criterion; changes urgency
Skin, hair, hands — lanugo, Russell’s sign, peripheral vascular signsLanugo hair (fine downy hair on trunk, face, arms): indicates severe prolonged starvation; thermoregulatory adaptation to heat loss from lack of subcutaneous fat. Not specific but indicates chronicity. Russell’s sign (calluses on dorsum of hand from teeth): specific for self-induced vomiting; confirms purging behaviour — important to distinguish AN restricting from AN binge-purge type (or BN). Peripheral vasoconstriction (cold blue extremities; Raynaud’s): malnutrition plus poor peripheral perfusion. Parotid swelling (sialosis): bilateral parotid gland hypertrophy from chronic purging in BN. Dental erosion: enamel erosion from gastric acid during vomiting — assess teeth and ask about dental health.Russell’s sign: confirms purging — changes to BN or AN binge-purge subtype; electrolytes urgently (K+ depletion). Lanugo: severity/chronicity indicator. Parotid enlargement: confirms purging; dental referral. No signs: AN restricting type (Emma’s picture).YES — Russell’s sign changes subtype and management
🎓 SCA Checkpoint — Step 3Tasks
Examination communication
"I want to do a few physical checks — your pulse, blood pressure, and I’ll check your strength by asking you to stand up from the chair. I also want to weigh you today — not to put pressure on you about a number, but because it helps me track how your body is doing and gives me information for the referral. Is that OK?"
Deductions
  • Not checking pulse — bradycardia is the most important MEED physical criterion and the one most likely to change management urgency
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Step 4
Investigations — ECG · Electrolytes · Glucose · DEXA · Pregnancy Test
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Investigations in eating disorders serve two purposes: MEED physical risk stratification (electrolytes; ECG; glucose determine whether hospital admission is needed today) and physical complication monitoring (bone density; renal; liver; FBC).
InvestigationWhy indicatedResult changes management
ECG — at every initial assessment and at key BMI thresholdsQTc prolongation is a major cardiac mortality risk in AN: from hypokalaemia; hypophosphataemia; hypomagnesaemia; direct cardiac effects of malnutrition. QTc normal: <440ms women; <420ms men. MEED threshold: QTc >450ms women / >430ms men = same-day cardiology review. Also check: HR (bradycardia on ECG confirms clinical finding); PR interval; evidence of VT or SVT on rhythm strip. Vigorous exercise with QTc prolongation = risk of fatal arrhythmia. Emma’s compulsive 2–3 hour daily exercise must be assessed in this context. SSRIs further prolong QTc — absolutely contraindicated in underweight AN patients with any QTc prolongation.QTc >450ms (F) / >430ms (M): MEED — same-day cardiology; stop exercise; stop QTc-prolonging medication; hospital if severe. QTc 420–450ms: urgent eating disorder referral; no vigorous exercise; electrolyte correction. Normal QTc: continue eating disorder management plan.
Electrolytes: Na+, K+, Ca2+, Mg2+, PO4(2−), urea, creatinineStarvation electrolyte pattern: hypokalaemia (particularly if purging); hyponatraemia; hypophosphataemia; hypomagnesaemia. Hypophosphataemia: critical in refeeding risk — low pre-refeeding phosphate predicts severe refeeding syndrome; must be corrected before nutritional rehabilitation begins. Hypokalaemia: MEED criterion if K+ <2.5; immediately dangerous for cardiac arrhythmia. Renal function: dehydration (elevated urea); renal tubular dysfunction from electrolyte wasting. In BN/AN binge-purge: hypochloraemia; metabolic alkalosis; elevated bicarbonate (from vomiting of gastric acid).K+ <2.5: MEED emergency; IV potassium hospital; cardiac monitoring. K+ 2.5–3.5: oral potassium replacement; eating disorder urgent referral. Low phosphate: high refeeding risk; phosphate supplementation pre-refeeding; specialist oversight of nutritional rehabilitation. Elevated urea: dehydration; oral fluids; monitor.
Blood glucose (random or fasting)Starvation hypoglycaemia: impaired hepatic gluconeogenesis; depleted glycogen stores. MEED criterion if <3 mmol/L. Hypoglycaemia in AN may occur without the usual adrenergic warning symptoms (sweating; tachycardia) — the patient may lose consciousness without warning. Particularly dangerous in Emma’s case: exercising for 2–3 hours daily while restricting food. Exercise hypoglycaemia risk. Also check in fasting state if possible — starvation glucose ← normal range may mask deranged hormonal responses.Glucose <3 mmol/L: MEED emergency; 999 if unconscious; oral glucose; hospital admission. Glucose 3–4 mmol/L: borderline; eating disorder urgent referral; no vigorous exercise; regular meals. Normal: reassurance; continue monitoring at each review.
FBC; LFTs; TFTs; amylase; bone profile (Ca2+, ALP)FBC: leucopaenia (bone marrow suppression from malnutrition); thrombocytopaenia; anaemia (iron, B12, folate deficiency). LFTs: mildly elevated transaminases common in AN from hepatic steatosis and fatty infiltration; elevated alkaline phosphatase may indicate bone metabolism (ALP from bone isoform). TFTs: “sick euthyroid syndrome” (low T3; normal TSH) in starvation — do NOT treat as hypothyroidism; it resolves with nutritional rehabilitation. Amylase: elevated in purging (salivary amylase from parotid gland stimulation) — confirms purging behaviour. Calcium: low from vitamin D deficiency; relevant to bone density.Leucopaenia or thrombocytopaenia: severity indicator; oncology/haematology if not consistent with malnutrition. Elevated amylase: confirms purging; subtype changes to AN binge-purge or BN. Low T3 (euthyroid sick): do NOT treat with thyroxine — will normalise with refeeding. Corrected calcium low: vitamin D and calcium supplementation.
Pregnancy test (urine hCG); DEXA bone density scan (if indicated)Amenorrhoea in a 19-year-old: always rule out pregnancy before attributing to eating disorder. Urine hCG: quick; sensitive; must be done. DEXA bone density scan: indicated if BMI <17.5 for >1 year (NICE NG69); or earlier if high suspicion. AN causes the most rapid bone density loss of any condition: hypo-oestrogenaemia (from amenorrhoea); low IGF-1; high cortisol; nutritional deficiency. Fracture risk significantly elevated even in young people. Prevention: weight restoration (primary intervention); calcium 1000–1500mg + vitamin D 800IU; HRT/OCP does NOT substitute for weight restoration in protecting bone density in AN.Pregnancy positive: immediate obstetric referral; eating disorder team alert (high-risk pregnancy + eating disorder). DEXA T-score <–2.5 (osteoporosis) or –1 to –2.5 (osteopaenia): calcium + vitamin D; weight restoration priority; do NOT use bisphosphonates in reproductive-age women (teratogenic). Negative pregnancy test: confirms amenorrhoea from AN; document and continue management.
🎓 SCA Checkpoint — Step 4Tasks
Investigations rationale
"I want to do some blood tests and an ECG — that is an electrical tracing of your heart. I also want to do a simple pregnancy test to rule that out as a reason for the periods stopping. The blood tests tell me about how your body is coping. I am specifically checking a few things — your potassium, your phosphate — which are minerals that can drop when the body is not getting enough, and which affect the heart. I want to know those results before I decide whether you need to be seen today or if the specialist referral can wait until next week."
Deductions
  • Not ordering ECG — QTc prolongation is a life-threatening MEED criterion and determines whether Emma can continue exercising; ECG is mandatory at first eating disorder assessment
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Step 5
Diagnosis — Plain Language · Types · Explaining Without Confrontation
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Explaining the diagnosis of an eating disorder to a patient who does not accept it as a problem is one of the most clinically skilled conversations in general practice. The goal is not to convince Emma she is wrong, but to introduce enough perspective that she can consider the possibility that her body needs support — framed around the things she values.
🗣️ Explaining the diagnosis without the “eating disorder” frame as the opening gambit

"I want to share some of the things I have noticed today. Your heart rate is lower than it should be for someone your age — that is the body’s way of conserving energy when it is not getting enough. Your periods have stopped — and that happens when the body decides it can’t safely support a pregnancy, so it turns off that system. These are not random things — they are connected, and they are connected to not getting enough nutrition. I am not saying this to criticise you or to tell you that what you have been doing is wrong — I am saying it because I want you to understand what your body is communicating. These are early warning signs that I need to take seriously, and so do you. The good news is that they are reversible — the periods come back; the heart rate comes back — with support."

💬 Addressing the “I’m just being healthy” narrative

"But I am healthy — I exercise and I eat clean."
"I hear that — and I can see that health matters a lot to you. But I want to show you what ‘healthy’ looks like from your body’s perspective. A healthy heart rate at your age is between 60 and 100 beats per minute. Yours is 52. A healthy body in a woman your age maintains periods — yours have stopped. Your body is telling me it is working harder than it should just to keep you going. That is not what a healthy body feels like on the inside."

"I don’t have an eating disorder — I’m not like those people you see in hospital."
"I understand why you think that. But eating disorders exist on a spectrum, and what I am seeing today — the heart rate, the periods, the weight — tells me your body needs help, whatever label we give it. I am not going to insist on a label. What I am going to do is make sure you see a team who can support you properly — and you will be in control of that conversation."

AN Restricting Type — Emma
Eating disorder service + GP monitoring
Significantly low BMI; fear of weight gain; distorted body image; amenorrhoea; excessive exercise (compensatory); no purging. NICE NG69 treatment: MANTRA (Maudsley AN Treatment for Adults); CBT-AN; nutritional rehabilitation. No medication first-line. MEED weekly physical monitoring in GP.
Bulimia Nervosa
Guided self-help + fluoxetine 60mg

Normal/near-normal BMI; binge-purge cycles

Russell’s sign; parotid swelling; dental erosion; hypokalaemia. NICE: guided self-help (CBT-BN) first; fluoxetine 60mg OD if psychological therapy unavailable; eating disorder service referral.

BED / ARFID / OSFED
Varied treatment pathways

BED: binge without purge; ARFID: sensory avoidance; OSFED: partial criteria

BED: guided self-help; lisdexamfetamine (NICE TA607). ARFID: dietitian + psychologist. All: eating disorder service referral per NICE NG69.

📊 Eating Disorder Classification — MEED Risk by BMI
BMI (adults)Risk categoryUrgencyGP action
>17.5Low physical risk (but SCOFF ≥2 still indicates eating disorder)RoutineSCOFF ≥2: routine eating disorder referral (4 weeks); monthly GP monitoring; ECG; electrolytes; DEXA if indicated
15–17.5 (Emma: 16.2)Moderate physical riskUrgent — 1 weekEating disorder service within 1 week; ECG; electrolytes; weekly GP physical monitoring; vigorous exercise restricted; calcium + vitamin D
13–15Very high physical riskSame daySame-day eating disorder team or medical admission; daily monitoring; consider inpatient admission; MHA if refusing and at serious risk
<13Life-threateningHospital todayHospital admission; MEED pathway; cardiac monitoring; refeeding under specialist supervision; MHA assessment if refusing
🎓 SCA Checkpoint — Step 5TasksRelating to Others
Diagnosis phrase — body-focused, not label-focused
"I am not going to insist on a label today. What I want to share is what your body is telling me: a heart rate below where it should be; periods that have stopped; a weight that is lower than your body can sustain comfortably. These things are connected. And they are reversible — with the right support. That is what I want to help you get."
Deductions
  • Insisting on the “eating disorder” or “anorexia” label in a patient who is ambivalent — provokes resistance; the body-focused framing is more effective and more empathetic
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Step 6
Referral — Eating Disorder Service · MEED Hospital · CAMHS (Under-18s)
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NICE NG69: refer to specialist eating disorder service without waiting for confirmed diagnosis. Do NOT refer to general CMHT. Do NOT delay until “things get worse.” Early referral is the single most impactful intervention a GP can make in eating disorder management.
Referral pathwayUrgencyWhat GP doesWhat NOT to do
Specialist eating disorder service (adult; Emma is 19)Urgent — 1 week (NICE NG69)Refer to adult specialist eating disorder service (not general CMHT). Include in referral: SCOFF score; BMI and rate of weight loss; MEED assessment (HR; BP; glucose; ECG findings; electrolytes); mental state (PHQ-9; suicide risk); psychosocial context (university; isolation; family). Alongside referral: GP continues weekly physical monitoring (BMI; HR; BP; electrolytes; ECG if indicated) until eating disorder team takes over care. Calcium + vitamin D prescribed. Exercise restriction advised (MEED; bradycardia). Safety-netting for MEED emergency criteria.Do NOT refer to general CMHT — eating disorders require specialist teams. Do NOT wait for “confirmed diagnosis” — SCOFF ≥2 is sufficient to refer. Do NOT wait for weight to deteriorate further before referring. Do NOT offer food plans, dietary advice, or calorie targets — this must be managed by eating disorder dietitian. Do NOT start SSRIs in underweight AN (not effective; QTc risk).
MEED hospital referralSame day if MEED criteria metIf MEED criteria met at any GP appointment: same-day alert to eating disorder team; medical ward admission if cardiac or metabolic emergency. 999 if patient is unconscious, having a cardiac arrhythmia, or severely hypoglycaemic. IV access; cardiac monitoring; IV potassium under monitoring; IV Pabrinex if malnourished (thiamine before glucose). Mental Health Act: if patient refuses medically necessary admission and this refusal carries a real risk of death — MHA Section 2 or 3 assessment is appropriate. Eating disorder can impair capacity regarding food-related decisions even in patients who appear to have capacity in other domains.Do NOT allow patient to leave without safety plan if MEED criteria are met. Do NOT give IV glucose to malnourished patient before IV thiamine (Pabrinex). Do NOT treat euthyroid sick syndrome with thyroxine — resolves with nutritional rehabilitation. Do NOT start vigorous exercise in a patient with bradycardia and pending electrolyte results.
CAMHS eating disorder pathway (under-18s)Urgent — 1 week (NICE NG69 target)Under-18: Child and Adolescent Mental Health Services eating disorder team. NICE NG69: urgent (1 week) for high-risk; routine (4 weeks) for lower risk. Parental involvement: appropriate for most under-18s with eating disorders; discuss with young person; Fraser competence if refusing parental involvement. School nurse involvement; school absence monitoring. FBT (Family-Based Treatment) is first-line for adolescent AN in UK guidelines.Do NOT manage adolescent eating disorders in adult eating disorder services without CAMHS involvement. Do NOT exclude parents from assessment unless good reason (and document why). Do NOT miss school refusal as an indicator of eating disorder severity in young people.
🎓 SCA Checkpoint — Step 6Tasks
Referral framing for Emma
"I want to refer you to a specialist team — they are specifically trained to support people with exactly what you are describing. This is not a hospital admission, not a weight clinic, and not someone going to tell you what to eat. It is a team of psychologists, dietitians, and doctors who will listen to what your life is like and help you work out what you want it to look like. And you will be in control of that conversation. I would like to speak to them this week — is that something you can agree to?"
Deductions
  • Referring to general CMHT instead of specialist eating disorder service — NICE NG69 is explicit: eating disorder service, not CMHT; outcomes are significantly worse with CMHT management
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Step 7
Management — MEED Monitoring · Nutritional Rehab · Medications · Psychosocial · Safety
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7A — Address Emma’s core fear before anything else
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Emma’s fear is that the GP will take control of her eating — the one thing that feels manageable
1
Name the fear before it is stated

Most patients with AN who come to a GP appointment are convinced the GP is going to tell them to eat more, gain weight, or go to hospital. Naming this fear directly — before Emma does — demonstrates that the GP understands her situation and disarms the most common defensive response.

"I want to say something before we go any further. I am not going to hand you a meal plan. I am not going to tell you what to eat or how much. And I am not going to call your parents today without your agreement. What I want to do is make sure your body is safe — and to introduce you to a team who can actually help."
2
Validate the control function without endorsing the restriction

Emma’s restriction is working for her in one sense: it provides a sense of control. Asking her to give this up without understanding it — and without offering anything in its place — will fail. The GP who acknowledges the function of the behaviour while being clear about the physical consequences creates the cognitive dissonance needed for change.

"I understand that the way you’ve been eating and exercising gives you a sense of being in control of something when a lot of other things have felt uncertain since you started university. That makes sense to me. What I want to show you is what that control is costing your body — and that there are other ways to feel in control that don’t carry these costs."
3
Frame the referral as expanding options, not removing them

The referral to an eating disorder service must be framed not as a loss of control (which is Emma’s fear) but as gaining access to a team who can help her achieve the things she actually values — energy to study; feeling warm again; having her periods return; being a full participant in university life. The eating disorder is taking those things away; the eating disorder team can help her get them back.

"The team I want to refer you to — they are going to ask you about your life, what matters to you, what you want your time at university to look like. They will not force anything on you. What they will do is help you think about whether the way things are going right now is actually getting you to where you want to be."
7B — Treatment goals
Immediate and medium-term goals
IMMEDIATE: physical safety — MEED monitoring weekly; ECG; electrolytes; calcium + vitamin DIMMEDIATE: vigorous exercise restriction advised (bradycardia + pending electrolytes = cardiac arrhythmia risk during exercise) URGENT: eating disorder service referral within 1 week (NICE NG69 urgent pathway); GP to contact service todayWeekly GP physical monitoring until eating disorder team takes over; BMI; HR; BP; electrolytes MEDIUM-TERM: psychological therapy (MANTRA or CBT-AN) with eating disorder team; nutritional rehabilitation under dietitian supervisionUniversity welfare officer referral (with Emma’s consent); Priya as welfare contact; PHQ-9 for depression monitoring Calcium 1000–1500mg/day + vitamin D 800IU (bone density protection); pregnancy test; DEXA if indicatedFamily contact: with Emma’s consent, encourage disclosure to family; family support may facilitate recovery
Motivational language — values-based
"You mentioned you want to be healthy. I want to show you what your body is saying about that right now. Your heart rate, your periods, your energy levels — these are your body’s health report. Right now they are telling us something needs to change."
"What does university look like when you are fully well? Being at lectures with energy, eating with your flatmates, exercising because you enjoy it rather than because you have to — that is what the eating disorder team can help you get back to."
7C — GP-delivered physical monitoring during eating disorder treatment
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Weekly Physical Monitoring
BMI; HR; BP sitting + standing; glucose
Why weekly

Until the eating disorder service has assessed and taken over care, the GP is the primary physical safety monitor. Weekly reviews track: BMI trajectory (improving, static, or deteriorating); HR (bradycardia resolving or worsening); postural BP; energy level. MEED threshold assessment at every visit. Any visit where MEED criteria are newly met: same-day hospital referral regardless of eating disorder team appointment timing.

Practical

Brief appointments (10–15 minutes) focused on physical parameters. Document each value with date. Graph BMI over time — visual trajectory is more meaningful than a single measurement. If patient refuses weighing: document; safety-net for physical indicators; escalate to eating disorder team. Do NOT create a punitive atmosphere around weighing.

Weekly GP monitoring in AN reduces rate of emergency hospital admissions and improves prognosis by catching deterioration early
Calcium + Vitamin D
Calcium 1000–1500mg/day; vitamin D 800–1000IU/day
Why essential in AN

AN causes the most rapid bone density loss of any condition in young people: hypo-oestrogenaemia from amenorrhoea; low IGF-1 (growth hormone insensitivity in starvation); high cortisol; inadequate dietary calcium and vitamin D. Fracture risk elevated even in young patients. Bone density loss begins within weeks of amenorrhoea. Osteoporosis may be established by the time treatment begins.

Important caveats

Calcium + vitamin D supplementation: prescribed from first GP assessment; does NOT replace weight restoration as the primary bone protection intervention; weight restoration is the most effective intervention for bone density recovery. OCP does NOT protect bone density in AN (NICE NG69). Bisphosphonates: NOT recommended in reproductive-age women (teratogenic; long half-life; potential foetal harm). DEXA scan: if BMI below 17.5 for more than 1 year.

Calcium 1000–1500mg + vitamin D 800IU: prescribed from first GP assessment to minimise ongoing bone loss during eating disorder treatment
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Exercise Advice
Vigorous exercise restriction until ECG and electrolytes cleared
Clinical rationale

Emma exercises 2–3 hours daily with a resting HR of 52 bpm and pending electrolyte results. Vigorous exercise while bradycardic and potentially hypokalaemic or hypophosphataemic carries a genuine risk of exercise-induced fatal arrhythmia (QTc prolongation + catecholamine surge during exercise = Torsades de Pointes risk). This must be communicated clearly and without ambiguity to Emma. Light activity (walking; gentle stretching) can continue; structured vigorous aerobic exercise must stop until cleared.

How to frame it

"I want to be clear about one thing before you leave. Until we have your blood test results back and your heart trace has been reviewed, I need to ask you not to do your usual exercise sessions. I know this will be difficult — and I want to acknowledge that. But the combination of your heart rate and the tests I am waiting for means that vigorous exercise right now carries a real cardiac risk. Light walking is fine. This is temporary, not permanent."

Exercise restriction until cardiac safety confirmed: prevents exercise-induced arrhythmia in bradycardic patients with potentially deranged electrolytes
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University Welfare Support
University welfare officer; student support; disability service
Why multi-agency

Emma is a first-year university student: her eating disorder is both a clinical problem and a welfare and academic problem. University welfare officers can: monitor attendance and academic performance; arrange academic accommodations (essay extensions; mitigating circumstances); connect Emma with student counselling. The eating disorder and academic performance are interlinked — cognitive function is impaired by malnutrition; concentration and memory decline. Addressing the academic stress simultaneously with the eating disorder improves overall outcomes.

With consent

Contact university welfare officer with Emma’s explicit consent. Do NOT contact the university, Priya, or Emma’s family without her consent (she is 19 — adult). Discuss consent explicitly: "Would it be helpful if I wrote a letter to your university welfare office — you do not have to give them any details you do not want to share."

Multi-agency support (eating disorder service + university welfare + GP) improves engagement and reduces dropout from treatment
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Social Connection
Address isolation; Priya as welfare contact; social eating rehabilitation
Why isolation matters

Emma eats alone in her room; avoids communal meals; has declined social invitations. Social isolation is both a symptom and a perpetuator of the eating disorder — it removes corrective social experiences and deepens the illness-driven food rules. Social eating rehabilitation (eating with Priya even one meal per week) is a therapeutic target in eating disorder treatment. Priya (who brought Emma to the GP) is already a welfare resource — with Emma’s consent, supporting her in social engagement is clinically beneficial.

Priya’s role

Priya is in the waiting room. With Emma’s agreement: Priya can be informed of the referral (not of clinical details); can be a welfare contact for the community; can be asked to check in with Emma during the week. Do NOT assign Priya an eating disorder monitoring role — that is the eating disorder team’s responsibility.

Social connection and peer support (Priya; student services) reduce isolation and support engagement with eating disorder treatment
🤯
Depression and Suicide Risk
PHQ-9 at every review; direct enquiry; crisis plan if positive
Why this matters

Suicide is the second most common cause of death in AN after cardiac causes. Depression is present in the majority of patients with AN (secondary to starvation; biochemical effects of low weight; social isolation; psychosocial stressors). PHQ-9 at every review. Direct suicide risk assessment: "Sometimes when people are going through something as difficult as this, they have thoughts of not wanting to be here — have you had any thoughts like that?" Mandatory question in every eating disorder consultation. Crisis plan: Samaritans 116 123; university mental health crisis line; A&E if immediate risk.

Treatment note

Depression in AN: antidepressants (SSRIs) are NOT effective in underweight patients (NICE NG69; insufficient serotonin substrate in malnutrition) AND carry QTc prolongation risk. Do NOT prescribe SSRIs for comorbid depression in underweight AN — treat the malnutrition first; reassess depression at healthy weight.

PHQ-9 + direct suicide enquiry at every eating disorder consultation: addresses the second leading cause of mortality in AN
7D — Prescribing
Anorexia nervosa: no NICE-approved first-line medication; SSRIs not effective in underweight AN and QTc risk; nutritional rehabilitation is the primary treatment. Bulimia nervosa: fluoxetine 60mg OD (NOT 20mg) first-line (NICE NG69). BED: lisdexamfetamine (NICE TA607) for moderate-to-severe; specialist initiation. ALL patients: calcium + vitamin D. Never prescribe SSRIs in underweight AN. Never give dietary or calorie advice — this is the eating disorder dietitian’s role.
AN — No First-Line Medication
  • No NICE-approved pharmacotherapy for AN. Nutritional rehabilitation (via eating disorder dietitian and specialist team) is the primary treatment.
  • SSRIs: NOT effective in underweight AN (serotonin synthesis requires adequate tryptophan from nutrition; NICE NG69) AND carry QTc prolongation risk in a patient with existing bradycardia and electrolyte derangement. Do NOT prescribe for Emma.
  • Olanzapine: off-label; some evidence for reducing anxiety and supporting weight gain at very low doses (2.5–5mg); specialist decision; not GP-initiated.
  • Prescribe from first assessment: calcium 1000–1500mg/day + vitamin D 800IU (bone protection). Vitamin B complex if nutritionally depleted.
BN — Fluoxetine 60mg (NOT 20mg)
  • Fluoxetine 60mg OD: NICE NG69 first-line pharmacotherapy for BN. Reduces binge-purge frequency by approximately 50%. Evidence: NICE systematic review. The dose is 60mg OD — NOT the standard 20mg antidepressant dose. This is a commonly missed prescribing distinction in SCA examinations.
  • Start at 20mg; increase to 60mg over 1–2 weeks if tolerated. Can be combined with CBT-BN (guided self-help) for enhanced outcomes.
  • Not effective for AN (weight normalisation is required first). Not appropriate for Emma in her current underweight state.
  • Monitor: electrolytes (K+ from purging); dental referral; eating disorder service.
BED — Lisdexamfetamine (NICE TA607)
  • Lisdexamfetamine (Vyvanse) 30mg OD, titrated to 50–70mg OD: licensed for moderate-to-severe BED (≥3 binge eating episodes/week for ≥3 months). NICE TA607 (2019).
  • Only licensed pharmacotherapy specifically for BED. Controlled drug (Schedule 2); prescribing: 4-week supply maximum; specialist initiation recommended.
  • Mechanism: CNS stimulant; reduces binge eating frequency; reduces compulsive eating. Not a weight loss drug — the licensed indication is specifically BED.
  • CI: cardiovascular disease; hypertension; hyperthyroidism; history of substance misuse. Monitor: BP; HR; weight; mood; risk of stimulant misuse.
7E — Medication selector

Select eating disorder subtype — management guidance

Eating disorder management guidance
Anorexia nervosa: no NICE-approved first-line medication; nutritional rehabilitation via eating disorder team is primary treatment; SSRIs NOT effective in underweight AN (not enough serotonin substrate) AND QTc risk; olanzapine: off-label; specialist only; prescribe calcium 1000–1500mg + vitamin D 800IU from first assessment. Underweight AN + SSRIs being considered: CONTRAINDICATED in underweight state; QTc prolongation risk on already vulnerable cardiac substrate; treat malnutrition first. Bulimia nervosa: fluoxetine 60mg OD (NOT 20mg); guided self-help (CBT-BN); eating disorder service referral. BED (moderate-severe): lisdexamfetamine 30mg OD (NICE TA607); controlled drug; specialist initiation; CI cardiovascular disease / hypertension / substance misuse. MEED emergency: 999 or same-day hospital; IV access; cardiac monitoring; IV Pabrinex (thiamine) before glucose if malnourished; IV potassium under monitoring if severely hypokalaemic. Depression in AN: do NOT treat with SSRIs until weight restored; reassess PHQ-9 at healthy weight; many depressions resolve with nutritional rehabilitation; olanzapine if severe anxiety: specialist only.
7F — Drug reference cards
Fluoxetine 60mg (Bulimia Nervosa)
60mg OD — NOT 20mg · NICE NG69 first-line pharmacotherapy for BN · Reduces binge-purge frequency ~50%
✓ BN first-line pharmacotherapy — 60mg OD; start at 20mg and titrate
BN with normal weight; NOT for underweight AN (QTc risk)Start fluoxetine 20mg OD; increase to 60mg OD over 1–2 weeks; morning dosing (activating)
✓ When to prescribe and at what dose
NICE NG69 first-line pharmacotherapy for bulimia nervosa. Evidence: reduces binge-purge frequency by approximately 50%; effect independent of antidepressant action. The dose is 60mg OD — this is one of the most commonly examined prescribing distinctions in SCA (candidates often prescribe 20mg, the standard antidepressant dose). Start at 20mg OD; increase to 60mg over 1–2 weeks if tolerated. Combine with guided self-help (CBT-BN) for enhanced outcomes. Use in normal-weight BN. NOT appropriate for underweight AN (not effective; QTc risk). For comorbid depression in BN: fluoxetine at 60mg also addresses depression — do not add a second SSRI.
✗ When NOT to prescribe — underweight AN
CONTRAINDICATED in underweight anorexia nervosa: (1) SSRIs are not effective in underweight AN — serotonin synthesis requires adequate tryptophan from diet; malnutrition depletes the substrate for serotonin production; (2) QTc prolongation — SSRIs (especially citalopram, escitalopram) prolong QTc; in AN patients with pre-existing bradycardia, electrolyte disturbance, and cardiac atrophy, any further QTc prolongation increases risk of fatal arrhythmia. NICE NG69: do not routinely offer antidepressants for AN. If treating comorbid severe depression in AN at healthy weight: fluoxetine is the preferred SSRI (least QTc effect); confirm normal QTc on ECG first.
Seizure disorder: caution (reduces seizure threshold). Hepatic impairment: use with caution. Serotonin syndrome: avoid concurrent MAOIs (2-week washout). QT-prolonging drugs: avoid combining with other QTc-prolonging agents.
⚠ Side effects
Nausea (common early; take with food; settles). Insomnia (activating — take in the morning). Headache. Anxiety (early; settles). Sexual dysfunction. Weight change. Increased suicidal ideation in under-18s — MHRA black box warning; monitor closely in young people; weekly review for first 4 weeks if under 18. SSRI discontinuation syndrome if stopped abruptly (less pronounced with fluoxetine than other SSRIs due to long half-life).
🔬 Monitor
PHQ-9 at 2, 4, 8 weeks. ECG before starting (QTc confirmation). Electrolytes (particularly K+ in BN from purging). Review frequency of binge-purge episodes at 4 weeks (treatment response). Dental review (acid erosion from purging). Continue eating disorder service engagement alongside medication. Duration: treat for 6–12 months; discuss discontinuation with eating disorder team.
💬 Counselling — BN patient

"This tablet helps with the cycle you have been describing — the urge to eat and then the need to compensate. It does not make the urges disappear overnight, but over 4–6 weeks most people find those urges come less often and are less intense. The dose I am giving you is higher than the standard antidepressant dose — 60mg — because that is the dose that works for this. Take it in the morning with food. It may make you feel a bit anxious or nauseous in the first couple of weeks — this settles."

Fluoxetine for BN: dose is 60mg OD — NOT 20mg (one of the most common SCA prescribing errors in eating disorders). Start at 20mg; titrate to 60mg over 1–2 weeks. NICE NG69 first-line pharmacotherapy for BN. NOT for underweight AN (not effective; QTc risk). Combine with guided self-help (CBT-BN). PHQ-9 monitoring. MHRA: increased suicidal ideation under-18s — weekly review first 4 weeks. ECG before starting in any patient with eating disorder (QTc baseline).

Lisdexamfetamine (Vyvanse) — BED
30mg OD titrated to 50–70mg OD · NICE TA607 · Only licensed treatment for BED · Controlled drug (Schedule 2)
✓ Moderate-to-severe BED — specialist initiation; Schedule 2; NICE TA607
BED: ≥3 binge episodes/week ×≥3 months; failed guided self-help; specialist initiation30mg OD for 1 week; titrate to 50mg OD (2 weeks) then 70mg OD; maximum 70mg OD; morning dose
✓ NICE criteria for BED (NICE TA607, 2019)
Licensed for moderate-to-severe binge eating disorder defined as ≥3 binge eating episodes per week for ≥3 months with significant distress. The ONLY medication with a licensed indication specifically for BED. Mechanism: prodrug of dextroamphetamine; reduces compulsive binge eating via dopamine/noradrenaline reuptake inhibition; reduces impulsivity and food cue reactivity. Evidence: BED frequency reduction of 50–70% vs placebo in clinical trials. Combined with psychological therapy (guided self-help or CBT for BED) for optimal outcomes. Prescribing: 4-week supply; controlled drug Schedule 2; consider specialist initiation before GP continuation; document in controlled drug register.
✗ Contraindications
Cardiovascular disease (any significant CVD: arrhythmia; structural heart disease; hypertension requiring medication). Hyperthyroidism. History of substance misuse (stimulant; alcohol; drug). Agitated states or mania. Concurrent MAOIs (or within 14 days of stopping). Glaucoma. Pregnancy and breastfeeding. Patients in whom stimulant misuse is a concern: consider alternative approaches.
Hypertension (mild-moderate): caution; monitor BP; may need dose reduction. Anxiety disorders: may worsen anxiety initially. Tics. Seizure disorder. Bipolar disorder: risk of precipitating manic episode; specialist supervision.
⚠ Side effects
Decreased appetite (expected; monitor for progression to restrictive eating — particularly important in a patient being treated for BED). Insomnia (take in the morning; avoid late afternoon dosing). Dry mouth. Headache. Increased HR and BP (monitor at every review). Anxiety. Irritability. Weight loss (usually modest at licensed doses). Risk of misuse and dependence (stimulant; Schedule 2; monitor for diversion; consider urine drug screen). Psychiatric: new or worsening psychosis; mania; aggression — stop and review if any of these develop.
🔬 Monitor
BP and HR at every review (stimulant effects; weekly initially; monthly once stable). PHQ-9 and mood assessment (risk of mania in bipolar; risk of anxiety). Weight: BED patients often obese — monitor weight trajectory; not the primary target but relevant to comorbidities. BED episode frequency: patient diary or structured questionnaire. Misuse potential: controlled drug supply; review at each appointment. Drug interactions: MAOIs (absolute CI); tricyclic antidepressants (hypertensive crisis). Annual medication review including continued indication.
💬 Counselling

"This medication helps reduce the urge to binge — it works on the parts of the brain that drive compulsive behaviour. You might notice your appetite is lower during the day — that is a normal effect. Take it first thing in the morning — if you take it in the afternoon it can affect your sleep. I want to know about any changes in your mood, your heart rate, or if you feel anxious. Because it is a controlled drug, I will prescribe a month’s supply at a time and we will review it regularly."

Lisdexamfetamine (BED): NICE TA607; only licensed medication for BED; moderate-to-severe (≥3 episodes/week ×≥3 months). Schedule 2 controlled drug; 4-week supply; specialist initiation. CI: cardiovascular disease; hypertension; substance misuse history; MAOIs; hyperthyroidism; pregnancy. Monitor: BP; HR; mood; BED frequency; misuse potential. Side effect: decreased appetite — monitor for restrictive eating in BED patients. Not for AN or BN. Morning dosing only.

Calcium + Vitamin D (Bone Protection in AN)
Calcium 1000–1500mg/day + Vitamin D 800–1000IU/day · Prescribed from first assessment · Does NOT replace weight restoration
✓ All AN patients — prescribed at first GP assessment alongside eating disorder referral
AN: start at first assessment; continue throughout treatment; review annuallyCalcium carbonate 1000–1500mg/day (with food for absorption); cholecalciferol (D3) 800–1000IU OD or 20,000IU weekly
✓ Why mandatory in AN
AN causes the most rapid bone density loss of any condition in young people: hypo-oestrogenaemia from amenorrhoea (oestrogen is essential for bone maintenance); low IGF-1 (growth hormone resistance in starvation depletes bone formation signals); elevated cortisol (starvation-induced hypercortisolaemia directly inhibits osteoblast activity); inadequate dietary calcium and vitamin D intake. Fracture risk significantly elevated even in young patients (stress fractures during exercise particularly common — relevant to Emma’s 2–3 hour daily running). Bone density loss begins within weeks of amenorrhoea. NICE NG69: calcium + vitamin D prescribed as adjunct from first assessment. DEXA: if BMI below threshold for more than 1 year.
✗ Critical prescribing caveat
Bisphosphonates (alendronate, risedronate): NOT recommended in reproductive-age women with AN (NICE NG69). Teratogenic; very long half-life (years in bone); risk of foetal harm if patient becomes pregnant during or after treatment. Calcium + vitamin D supplementation cannot replace weight restoration as the primary bone protection intervention — weight restoration is the most effective and only reliable method of reversing bone density loss in AN. OCP (oral contraceptive pill): does NOT protect bone density in AN — this is a common clinical misconception (NICE NG69; evidence clearly shows OCP does not substitute for weight restoration in bone protection in AN).
Hypercalcaemia: calcium supplements should not be given if hypercalcaemia present (check corrected calcium before prescribing). Renal stones: caution with high-dose calcium in patients with renal stone history.
⚠ Monitoring — bone density
DEXA bone density scan: indicated if BMI below threshold for more than 1 year (NICE NG69); sooner if clinical concern. DEXA T-score: –2.5 or below = osteoporosis; –1.0 to –2.5 = osteopaenia. Both indicate high fracture risk in a young patient. Annual DEXA repeat while BMI below threshold. Weight restoration targets: eating disorder team sets weight restoration targets as part of treatment; GP monitors BMI trajectory. Bone density recovery: partial recovery occurs with weight restoration; but some permanent loss may persist if illness is prolonged.
🔬 Practical prescribing
Calcium carbonate tablets: 1000–1500mg/day in divided doses; taken with food (acidic stomach environment improves absorption; relevant given poor nutrition). Cholecalciferol (vitamin D3): 800–1000IU daily; or weekly higher dose (20,000IU) for adherence. Combined preparations available (e.g. Adcal-D3; Calcichew-D3 Forte). Check corrected calcium at baseline (before prescribing) and annually. These are safe and cheap — no reason not to start at first GP assessment for any patient with AN.
💬 Counselling

"I want to prescribe you a vitamin supplement — calcium and vitamin D. These help protect your bones. When periods stop for any reason, the bones can weaken quite quickly because they need oestrogen to maintain their density. These tablets help slow that process while we work on the bigger picture. They do not fix the problem on their own — but they are an important part of looking after you while treatment is underway."

Calcium + vitamin D: prescribed from first GP assessment in ALL AN patients with amenorrhoea or BMI below threshold. DOES NOT replace weight restoration as bone protection (NICE NG69). OCP does NOT protect bone in AN (common misconception). Bisphosphonates: NOT recommended in reproductive-age women with AN (teratogenic; very long half-life). DEXA: if BMI below threshold for >1 year. Calcium carbonate with food; cholecalciferol (D3) OD. Check corrected calcium at baseline. Annual DEXA review if ongoing low BMI.

Electrolyte Replacement (K+; PO4; Mg2+)
Oral or IV replacement · K+ <3.5: oral replacement · K+ <2.5: IV under cardiac monitoring · Pre-refeeding phosphate correction
✓ At first assessment — electrolytes determine MEED urgency and refeeding safety
Check electrolytes at every assessment; replace before refeeding (prevents refeeding syndrome)K+ 3.0–3.5: Sando-K 2–3 tablets TDS; K+ <3.0: higher oral or IV; K+ <2.5: hospital IV replacement
✓ Electrolyte monitoring in eating disorders
Electrolyte disturbances in AN/BN: hypokalaemia (purging — BN; renal wasting — AN); hypophosphataemia (starvation; refeeding risk); hypomagnesaemia; hyponatraemia; hypochloraemia (from vomiting of gastric acid in BN — metabolic alkalosis with hypochloraemia). MEED: K+ <2.5 = same-day hospital. K+ 2.5–3.5: oral replacement; eating disorder urgent referral. Phosphate: critically important before initiating nutritional rehabilitation — low pre-refeeding phosphate predicts severe refeeding syndrome. Correct phosphate (oral Phosphate-Sandoz or IV in hospital) before starting refeeding in severely malnourished patients. Magnesium: depleted in starvation; replace concurrently with potassium (hypomagnesaemia impairs potassium correction).
✗ Refeeding syndrome — the critical complication
Refeeding syndrome: occurs during nutritional rehabilitation of severely malnourished patients. Mechanism: refeeding stimulates insulin release → glucose drives electrolytes intracellularly → plasma hypophosphataemia; hypokalaemia; hypomagnesaemia → cardiac failure; arrhythmias; respiratory failure; seizures; Wernicke’s encephalopathy; death. Risk factors: severe malnutrition; rapid refeeding; no electrolyte pre-correction. Prevention: correct electrolytes BEFORE starting nutritional rehabilitation; start refeeding slowly (500 kcal/day increase from baseline); monitor electrolytes daily in inpatient setting; thiamine supplementation. This is managed by the specialist eating disorder team — NOT in GP — but GP must know not to encourage rapid weight gain without specialist oversight.
Oral phosphate (Phosphate-Sandoz): GI side effects (diarrhoea; nausea) — take with food. IV phosphate: hospital only; too-rapid replacement causes tetany and cardiac arrest. Replace phosphate before potassium if both low (phosphate is the higher priority pre-refeeding).
⚠ Practical electrolyte management in GP
Mild hypokalaemia (K+ 3.0–3.5 mmol/L): oral Sando-K (potassium bicarbonate + potassium chloride): 2 effervescent tablets in water TDS; review in 1 week. Mild hypophosphataemia: oral Phosphate-Sandoz (phosphate effervescent): 1–2 sachets TDS in water. Both: eating disorder urgent referral same week; weekly bloods until stabilised. Severe electrolyte disturbance (K+ <2.5; PO4 critically low): hospital same day. Never initiate nutritional rehabilitation in GP without eating disorder specialist oversight — risk of iatrogenic refeeding syndrome.
🔬 Monitor
Weekly electrolytes (Na+; K+; Ca2+; Mg2+; PO4; urea; creatinine) until eating disorder team establishes care. Pre-refeeding bloods: mandatory before any nutritional rehabilitation programme starts. ECG: QTc (affected by K+; Mg2+; Ca2+). If electrolytes worsen despite GP management: urgent eating disorder team or hospital medical team contact.
💬 Counselling

"The blood tests I am doing include checking some important minerals — particularly potassium and phosphate. These affect how the heart works. If they are low, I will prescribe replacement tablets. These are important to take — low potassium in particular can affect your heart rhythm."

Electrolytes: K+ <2.5 = MEED emergency; hospital same day. K+ 2.5–3.5: oral Sando-K; eating disorder urgent referral; weekly bloods. Phosphate: critically low pre-refeeding = high refeeding syndrome risk; must be corrected before nutritional rehabilitation begins. Refeeding syndrome: insulin during refeeding drives electrolytes intracellularly → hypophosphataemia; cardiac failure; respiratory failure; managed by eating disorder specialist team (not GP). Replace Mg2+ alongside K+ (hypomagnesaemia impairs K+ correction). ECG: QTc affected by all electrolytes.

Olanzapine (Off-Label in AN — Specialist Only)
2.5–5mg OD nocte · Off-label · Specialist initiation · Low evidence base · Not NICE first-line
⚠ Specialist decision only — not GP-initiated; off-label; low evidence; not NICE NG69 recommended
Specialist: off-label; low evidence; reduces anxiety in some AN patients; promotes small weight gain2.5mg nocte; max 5mg OD; lowest effective dose; avoid in QTc prolongation; specialist supervision required
✓ Limited clinical role in specialist practice
Olanzapine at low doses (2.5–5mg) is used off-label by some specialist eating disorder teams for AN where anxiety around eating is severe and refeeding is being resisted. Evidence base: small RCTs showing modest weight gain and anxiety reduction compared to placebo; no large high-quality trials; NICE NG69 does not recommend routine use. Mechanism: dopamine D2 and serotonin 5HT2 antagonism; reduces meal-related anxiety; stimulates appetite (side effect exploited therapeutically in AN). Also used for sleep (sedating). NOT appropriate for GP initiation. NOT appropriate for underweight patients unless under specialist supervision (QTc risk; metabolic effects).
✗ Why GPs should NOT initiate olanzapine for AN
NICE NG69: do not routinely offer antipsychotics to treat AN. Olanzapine: not first-line; off-label; specialist decision only. QTc prolongation: all antipsychotics prolong QTc; AN patients already have vulnerable cardiac substrate; ECG mandatory before starting and during treatment. Metabolic syndrome: olanzapine causes weight gain (which can be rapid in AN refeeding context), dyslipidaemia, type 2 diabetes — monitor fasting glucose and lipids. Oversedation: in malnourished patients with low body mass, drug levels may be disproportionately elevated at standard doses — start at lowest possible dose (2.5mg) and titrate slowly.
Parkinson’s disease: avoid (dopamine antagonism). History of severe metabolic syndrome: use with caution; monitor glucose and lipids. Hepatic impairment: dose reduction; accumulation risk.
⚠ Monitoring if specialist has initiated
GP continuation role (if specialist has initiated): ECG at baseline and at 3-monthly review (QTc monitoring). Fasting glucose and lipids (metabolic side effects). Blood pressure. Weight (eating disorder team will monitor separately). Mental state: psychosis; akathisia; mood. Annual medication review with specialist team. If QTc increases >30ms from baseline: discuss with specialist; consider dose reduction or discontinuation.
🔬 SCA teaching point
In an SCA examination: if asked about medication for anorexia nervosa — the correct answer is "there is no NICE-approved first-line medication for AN; nutritional rehabilitation is the primary treatment; SSRIs are not effective in underweight patients and carry QTc risk." Olanzapine may be mentioned as an off-label specialist option, but only in that context. Prescribing olanzapine as a GP for AN without specialist involvement would be a significant clinical error in the examination context.
💬 Counselling (if specialist has initiated)

"This tablet has been prescribed by the specialist eating disorder team — it is not a standard prescription for your condition, and it works by reducing some of the anxiety around eating that can make things very difficult. It may make you feel a bit drowsy at first, particularly if you take it at night. I will be monitoring your heart tracing and some blood tests while you are on it."

Olanzapine in AN: off-label; specialist initiation only; NOT NICE NG69 recommended; low evidence base. GPs should NOT initiate for AN. If specialist has started: GP continues with ECG monitoring (QTc); fasting glucose (metabolic syndrome); weight; mental state review. Correct SCA answer for AN medication: "no NICE-approved first-line medication; nutritional rehabilitation is primary treatment; SSRIs not effective in underweight AN." QTc prolongation risk — ECG mandatory before and during treatment.

Thiamine / IV Pabrinex (Refeeding and Wernicke’s Prevention)
Oral thiamine 100mg TDS (prophylaxis) · IV Pabrinex in hospital (refeeding; Wernicke’s) · Thiamine BEFORE glucose in malnourished patients
✓ All severely malnourished patients — thiamine before any glucose in acute setting
Malnourished AN patients; before refeeding; before IV glucose in any acute presentationOral thiamine 100mg TDS (community); IV Pabrinex 1–2 pairs daily (hospital refeeding prophylaxis)
✓ Why thiamine in eating disorder management
AN patients are frequently thiamine-deficient from chronic dietary restriction. Thiamine (vitamin B1) is essential for glucose metabolism. Giving glucose (IV dextrose; food refeeding) to a thiamine-deficient patient without replacing thiamine first: the sudden glucose load drives pyruvate dehydrogenase (thiamine-dependent) to exhaustion → toxic pyruvate and lactate accumulation → Wernicke’s encephalopathy damage to periventricular structures. The rule: THIAMINE BEFORE GLUCOSE applies in eating disorders exactly as it does in alcohol-related malnutrition. Prescribe oral thiamine 100mg TDS for any patient with AN who is nutritionally depleted.
✗ When oral thiamine is insufficient
Severe malnutrition with vomiting or impaired GI absorption: oral thiamine absorption is poor; IV Pabrinex (1–2 pairs daily) prescribed in hospital during supervised refeeding. Wernicke’s encephalopathy features in AN patient (confusion + ataxia + ophthalmoplegia): IV Pabrinex 2 pairs TDS × 3–5 days; hospital admission; 999 if acutely unwell. Inpatient refeeding protocol: IV Pabrinex 1 pair OD for duration of active refeeding under specialist supervision.
Anaphylaxis risk with IV Pabrinex: give slowly over 30 minutes; resuscitation equipment available. IM Pabrinex: lower anaphylaxis risk than IV; useful if IV access not available.
⚠ B-vitamin complex for Emma (community)
For Emma (BMI 16.2; nutritionally depleted; restricting diet): prescribe oral thiamine 100mg TDS plus Vitamin B Compound Strong (B2, B6, nicotinamide) alongside calcium + vitamin D. These are cheap, safe, and address the nutritional deficiencies that accumulate with dietary restriction. Folate 5mg OD if folate deficiency on bloods. B12: check and supplement if deficient. This supportive nutritional care in the community is the GP’s contribution to nutritional rehabilitation pending eating disorder team assessment.
🔬 Monitor
If signs of Wernicke’s develop (confusion; ataxia; eye movement abnormality): 999 immediately; IV Pabrinex before any IV glucose in the ambulance or A&E. B12 and folate at baseline. Repeat at 6–8 weeks. Annual monitoring of B vitamins during eating disorder treatment.
💬 Counselling

"I am going to prescribe some vitamin supplements — a B vitamin, a calcium tablet, and vitamin D. These are to support your body while we get the specialist team involved. They are not a replacement for proper treatment but they are important to start now."

Thiamine in AN: oral thiamine 100mg TDS for all nutritionally depleted AN patients in community. Thiamine BEFORE glucose: applies to ED patients as well as alcohol patients — any malnourished patient receiving IV glucose needs thiamine first. IV Pabrinex: hospital refeeding programme and Wernicke’s treatment. Refeeding syndrome (not managed in GP): slow refeeding + electrolyte pre-correction + thiamine + eating disorder specialist oversight. B complex + folate + B12 (if deficient) as part of community nutritional support alongside eating disorder referral.

7G — Psychosocial impact of having an eating disorder
🌟
The eating disorder as identity: what treatment means to Emma beyond weight restoration
Treatment for anorexia nervosa asks patients to give up something that is, paradoxically, providing important psychological functions. For Emma, the eating restriction is a coping mechanism, an identity, and a sense of control — perhaps the only thing that currently feels predictable and manageable. Weight restoration alone is not recovery. Recovery requires building alternative sources of control, identity, and wellbeing. The GP who understands this — and communicates it — is able to frame the eating disorder service referral as an expansion of Emma’s options rather than a threat to her autonomy.
🌟
Identity and the Disorder

The eating disorder often becomes a core identity in AN — “being the disciplined one”; “the one who doesn’t need much”. Recovery threatens this identity and requires the patient to rebuild a sense of self that is not organised around restriction. MANTRA (Maudsley Anorexia Nervosa Treatment for Adults) specifically addresses the meaning of the AN as a “valued and helpful identity.”

"Part of what we will explore with the team is what you get from things being the way they are right now — not to criticise it, but to understand it, and to think about whether there are other ways of getting those same things that do not cost your body this much."
🧠
Academic and Functional Impact

Malnutrition impairs cognitive function: concentration; memory; executive function; speed of processing. Emma is trying to succeed academically while cognitively compromised. Her academic performance is likely already suffering even if she does not recognise it. Weight restoration improves cognitive function — the eating disorder is making academic success less likely, not more.

"One thing people sometimes notice is that once the body gets what it needs, thinking becomes clearer — concentration improves; memory improves. The restriction that feels like discipline can actually be making it harder to do the things you care about, like your psychology course."
🤝
Relationships and Social Life

AN causes progressive social withdrawal: meal avoidance; declining social invitations; friendships organised around food; isolation. This social cost is often the patient’s most accessible point of ambivalence — Emma may recognise she has been withdrawing from Priya and others. Naming this gently — without blaming — introduces the social cost of the eating disorder as a reason for change.

"I noticed you mentioned avoiding the communal kitchen and eating in your room. How has that affected things with Priya and your other flatmates? I ask because sometimes the eating disorder starts to affect our relationships before we realise it."
🏃
Exercise and Physical Pleasure

Emma exercises 2–3 hours daily but this is compulsive exercise, not pleasurable activity. Compulsive exercise in AN generates anxiety rather than pleasure — missing a session causes distress disproportionate to the event. The GP’s observation: “you exercise a lot — but does it feel enjoyable, or does it feel like something you have to do?” creates a moment of self-reflection that can plant a seed for change.

"When you exercise — how does it feel? Is it something you look forward to, or is it more like something you have to do to feel OK? I ask because there is a difference between exercise that energises you and exercise that you are relying on in a way that has become compulsive."
7H — Follow-up
T
Today — Safety assessment, MEED review, investigations, prescriptions, referral

SCOFF documented (3/5). BMI measured and recorded. HR and BP (sitting and standing) documented. ECG performed. Blood tests: electrolytes; glucose; FBC; LFTs; TFTs; bone profile; amylase; B12; folate; pregnancy test. Prescriptions: calcium 1000–1500mg/day + vitamin D 800IU/day; thiamine 100mg TDS; B complex. Eating disorder service referral made today (urgent pathway; within 1 week). Exercise restriction advised (pending ECG and electrolyte results). Priya’s role discussed with Emma’s consent. PHQ-9 administered. Safety plan agreed. University welfare officer discussion (with consent).

Eating disorder service referral: urgent pathway — within 1 week
2
3–5 Days — Blood test and ECG results review

Phone or in-person review of ECG (QTc); electrolytes (particularly K+ and PO4); glucose; FBC. If MEED criteria met on results: same-day hospital referral. If mild electrolyte disturbance: oral replacement; eating disorder service contact. If all normal: continue current plan; confirm eating disorder service appointment received. Pregnancy test result discussed. Exercise advice confirmed based on ECG and electrolytes.

Results review: QTc and K+ determine whether exercise restriction continues or hospital needed
3
1 Week — Eating disorder service first appointment (NICE NG69 target)

Emma should have been seen by the specialist eating disorder team within 1 week (NICE NG69 urgent pathway). GP confirms attendance. If Emma did not attend: welfare check; re-engage; consider MHA assessment if significant deterioration. Weekly GP physical monitoring continues until eating disorder team confirms they have taken over care plan. Repeat BMI; HR; BP; MEED assessment.

Eating disorder service attendance confirmed; MEED reassessment
4
Monthly — Shared care physical monitoring

GP continues monthly physical monitoring (BMI; HR; BP; electrolytes) as part of shared care while eating disorder team manages psychological treatment and nutritional rehabilitation. PHQ-9 monthly. DEXA if BMI below threshold for 1 year. Annual review of calcium + vitamin D. MEED criteria reassessed at every visit — if met at any point: same-day hospital referral regardless of psychological treatment status.

Monthly: BMI; HR; BP; electrolytes; PHQ-9; MEED reassessment; shared care
7I — Monitoring — MEED physical safety at every contact

The MEED monitoring rule for every GP contact

At every GP appointment for a patient with an eating disorder, assess the MEED physical safety criteria: BMI (measured, not estimated); resting HR (<40 = emergency; 40–50 = urgent); standing and sitting BP (<80/50 = emergency; postural drop >20 mmHg = significant); blood glucose (<3 mmol/L = emergency); K+ (<2.5 mmol/L = emergency); QTc on ECG (>450 ms women = emergency); muscle strength (unable to stand from chair without arms = emergency). Any single criterion = same-day hospital regardless of eating disorder team appointment status.

7J — Safety-netting

⚠ Three safety-net conversations for Emma

🔴 Emergency — cardiac symptoms; collapse; loss of consciousness
"If you experience any heart racing, palpitations, chest pain, dizziness that makes you feel like you might faint, or any loss of consciousness — call 999 immediately or get Priya to call. Don’t wait. In the meantime, rest; don’t exercise; lie down. These symptoms could indicate your heart is under more strain than we thought."
Cardiac arrhythmia is the most common cause of sudden death in AN. Emma’s bradycardia (HR 52) and pending electrolytes mean there is a window of elevated risk. Exercise-induced arrhythmia is particularly relevant given her 2–3 hour daily exercise. The safety-net must be specific: naming palpitations, dizziness, and chest pain as emergency symptoms addresses the most likely presentations.
💊 Exercise — restriction until cleared
"Until we have the blood test and heart tracing results back, I need to ask you not to do your usual exercise sessions. I know this is significant for you, and I am not saying this to be restrictive — I am saying it because the combination of your heart rate and the tests I am waiting for means vigorous exercise right now carries a real risk. Light walking is fine. As soon as the results are back and we can confirm it is safe, I will let you know."
Exercise restriction in a patient with compulsive exercise is one of the most distressing aspects of eating disorder management. Framing it as temporary and evidence-based — with a specific trigger for lifting the restriction (results back and confirmed safe) — makes compliance more likely than a blanket "you must not exercise."
🟠 Eating disorder service — appointment acceptance
"I want to check that you have heard the appointment for the eating disorder team. If you do not hear from them within the next 3 days, please call me and I will follow up directly. If you feel you cannot go to the appointment — that is something I want to know about too, so we can talk about it. I am also going to call you in 3 days to check in, whether you have heard from them or not."
Non-attendance at eating disorder service appointments is common and the GP’s proactive contact within 3 days significantly improves engagement. The follow-up call also allows the GP to re-assess MEED criteria and detect any deterioration before the specialist appointment.
TodayUrgent eating disorder service referral; ECG + bloods; prescriptions; exercise restriction; Priya involvement with consent
3–5 daysGP phone call: results reviewed; eating disorder appointment confirmed; MEED reassessment
WeeklyPhysical monitoring until eating disorder team takes over care; MEED at every visit
🎓 SCA Checkpoint — Step 7 (Final)TasksRelating to OthersGlobal Skills
Closing the consultation
"I want to bring everything together. What I have found today concerns me enough that I want to refer you urgently to a specialist eating disorder team. Urgently means within the next week. This is not a hospital admission — it is a team who can genuinely help you."
"I also need to ask you not to do your usual exercise until we have your blood results and ECG back in the next few days. I know that is a big ask. It is temporary — and it is for a specific reason: your heart rate combined with the tests I am waiting for means vigorous exercise carries a real risk right now."
"I am prescribing calcium and vitamin D tablets, and a B vitamin. These help protect your bones and support your body while we get things in place."
"I want to check in with you in 3 days — I will call you — to make sure you have heard from the eating disorder team and to go through your blood results. And if at any point your heart races, you feel dizzy or faint, or you lose consciousness — call 999."
"Before you go — I have to ask about this directly. Sometimes when things are this difficult, people have thoughts of not wanting to be here. Has that come up for you at all?" [Pause, listen, respond appropriately.]
Deductions
  • Prescribing SSRIs for Emma’s mood — contraindicated in underweight AN; not effective; QTc risk; NICE NG69 does not recommend
  • Not referring to eating disorder service — or referring to CMHT instead — NICE NG69 specific: specialist eating disorder service
  • Waiting for confirmed diagnosis before referral — NICE NG69 mandates referral on SCOFF ≥2 without diagnostic confirmation
  • Not assessing suicide risk — AN has significant suicide mortality; PHQ-9 and direct enquiry mandatory
Tasks — full criteria
  • SCOFF administered and scored; MEED physical assessment complete
  • Eating disorder service referral: urgent; within 1 week; not CMHT
  • No SSRIs prescribed (underweight AN; QTc risk; not effective)
  • Calcium + vitamin D; thiamine; B complex prescribed
  • Exercise restriction advised (pending cardiac results)
  • ECG ordered (QTc); electrolytes (K+; PO4); pregnancy test
  • PHQ-9 and suicide risk assessed
Relating to Others
  • Reluctance acknowledged; Emma’s consultation not Priya’s
  • Illness model ("I’m being healthy") explored not confronted
  • Fear of weight gain addressed directly
  • Control function of restriction acknowledged
  • Referral framed as expanding options, not removing them
  • Non-label framing ("what your body is telling me")
🔴 Red
No SCOFF; opened with weight/BMI confrontation; SSRIs prescribed; referred to CMHT not eating disorder service; waited for confirmed diagnosis before referring; no suicide risk assessment; no MEED physical assessment; exercise not addressed
🟠 Amber
SCOFF performed; eating disorder service referral made; illness model not confronted; MEED partially assessed; suicide risk not directly assessed; no SSRIs; calcium + vitamin D forgotten; exercise not addressed
🟩 Green
Reluctance acknowledged; SCOFF ×5; MEED physical assessment complete (BMI; HR; BP; ECG; electrolytes); eating disorder service urgent referral (1 week); no SSRIs; calcium + vitamin D + thiamine; exercise restriction pending results; control function explored; illness model non-confrontational; suicide risk assessed; safety-net (cardiac symptoms = 999); GP 3-day phone follow-up; Priya role with consent
Eating Disorders — SCA Consultation Scorecard
NICE NG69 · MEED · SCOFF · AN / BN / BED · Fluoxetine 60mg (BN) · Lisdexamfetamine (BED) · No SSRIs in underweight AN
0/ 33 pts
🌐
Global Skills
Structure, non-confrontation, sensitivity
0/7
Tasks
Clinical reasoning, diagnosis, management
0/15
🤝
Relating to Others
Non-confrontation, motivation, safety
0/11
RAG Self-Assessment
🔴 Red
No SCOFF; BMI confrontation as opener; SSRIs prescribed for mood; referred to CMHT; waited for diagnosis before referring; no MEED assessment; exercise not addressed; suicide risk not assessed
🟠 Amber
SCOFF performed; eating disorder service referral; illness model not challenged; MEED partially assessed; no SSRIs; calcium and vitamin D forgotten; exercise not addressed; suicide risk not assessed
🟩 Green
SCOFF ×5; MEED complete; urgent eating disorder service referral (1 week; not CMHT); no SSRIs; calcium + vitamin D + thiamine; ECG + electrolytes + pregnancy test; exercise restriction pending results; control function acknowledged; illness model non-confrontational; suicide risk assessed; cardiac 999 safety-net; 3-day GP follow-up
011172533
Fail
Borderline
Pass
Strong pass
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"I don’t really know why I’m here. Priya thought I should come. I know I eat less than I used to but I’m being healthier — I feel better when I eat less and exercise more. I’m not like … I don’t have an eating disorder or anything."
Who you are

Emma Carter, 19, first-year psychology student at a city university. High achiever at school (3 A*s at A-level). First time living away from home. Parents are in the Midlands. Flatmate Priya (who came with her) has been her closest friend since starting university. She had a strong friendship group at school but has found it difficult to replicate that at university. She arrived 4 months ago and has been restricting what she eats since then; she tells herself this is about health and discipline. She runs for 2–3 hours daily before lectures. She eats in her room to avoid others seeing how little she eats. She knows something is wrong but is terrified of what it means to admit it. She is extremely bright and articulate — and uses that intelligence to deflect clinical questions.

Hidden details — disclose only if asked

Periods (disclose if asked directly): "They stopped about 3 months ago. I was a bit relieved — less hassle. Is that a problem?" Clearly does not connect this to her eating pattern; if GP links it: visibly unsettled.

Social isolation (disclose if asked about meals or friends): "I eat in my room. It’s just easier. I don’t want people watching me eat — or asking questions." If asked how she feels about eating with others: "It makes me anxious. I don’t know why."

Control (disclose if asked about why the exercise matters or what eating less feels like): "It’s the one thing I have got right since coming here. Everything else feels uncertain — the course is harder than I expected; I don’t know anyone really; home feels very far. But if I stick to what I eat and do my run, I feel like I have done something right." This is the key self-disclosure — the control function. If GP explores it: Emma becomes more thoughtful and less defensive.

Suicide (respond to compassionate direct enquiry): "Not exactly. I sometimes think things would be simpler if I just … stopped. Not in a dramatic way. Just … stopped." This warrants a PHQ-9 and careful safety assessment; she is not actively suicidal but is experiencing passive suicidal ideation. Crisis plan should be discussed; this should not end the consultation without a safety plan.

Reactions
  • On "you have an eating disorder / anorexia": defensive; closes down; "I knew you’d say that; I told Priya this was a waste of time." If GP avoids labels and uses body-evidence: more open.
  • On "I’m not going to tell you what to eat": visible relaxation; "OK. That’s … actually that’s helpful to hear."
  • On amenorrhoea linked to eating: genuine surprise; "I didn’t know those two things were connected." This is a moment of real engagement.
  • On control function named by GP: "Yes. That’s … exactly it. I hadn’t said that out loud before." Emotionally significant; GP should pause and stay with it.
  • On eating disorder service: initially resistant; if framed as "they will listen to what your life is like and help you decide what you want" — becomes cautiously open: "I suppose I could meet them once."
  • Challenge line: "If I go to the eating disorder team, they are going to make me gain weight, aren’t they? That’s what this is all about, isn’t it?"
Clinical details
  • BMI: 16.2 (weight 47 kg; height 1.70 m). Loss of approximately 8 kg since university (4 months ago).
  • HR: 52 bpm resting (borderline bradycardia)
  • BP: 112/68 sitting; 104/62 standing (mild postural drop — not significant)
  • Lanugo: absent. Russell’s sign: absent. Parotid: normal. No purging behaviour.
  • SCOFF: 3/5 (C, O, F positive)
  • PHQ-9: 14 (moderate depression; passive suicidal ideation Q9 = 1)
  • No significant PMH. No medications. No substance misuse. No family history of eating disorder that she knows of. Mother comments on food sometimes ("she’s always on some diet"). Father rarely comments on appearance.
"If I go to the eating disorder team, they are just going to make me gain weight, aren’t they? That’s what it’s all about. I don’t want that. I don’t see why that should be anyone else’s business."

Resolution: Emma agrees to attend the eating disorder service if: (1) the GP explicitly states they are not going to impose weight gain on her; (2) the control function is acknowledged without judgement; (3) the referral is framed as a conversation rather than a treatment mandate; (4) the amenorrhoea-eating connection is made clearly (a new piece of information that Emma finds genuinely engaging); (5) the cardiac safety concern is presented factually without alarmism; (6) Emma is told she will be called in 3 days. She says: "OK — I’ll go once. But I’m not promising anything." This is the realistic achievable outcome for this consultation.

🏥
Clinic Quick Reference
Eating Disorders — GP Framework
NICE NG69 · SCOFF · MEED · AN · BN · BED · Bone Protection · Refeeding
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🚨 1 — Triage Algorithm
Eating disorder concern → SCOFF ⇒ MEED physical risk ⇒ Emergency? ⇒ Subtype ⇒ Investigate ⇒ Prescribe / Refer ⇒ Safety-net ⇒ Follow-up
SCOFF screen (≥2/5 = positive): Sick · Control · One stone · Fat · Food — refer to eating disorder service without waiting for confirmed diagnosis
MEED physical risk: assess HR, BP, potassium, glucose, QTc, muscle power — any emergency criterion = 999 or urgent admission; none = eating disorder service referral within 1 week
Investigations (all cases): ECG (QTc), U&E (potassium), blood glucose, FBC, LFTs, TFTs, pregnancy test — do not defer pending specialist review
PHQ-9 + direct suicide risk: eating disorders carry highest psychiatric mortality; PHQ-9 Q9 ≥1 = direct compassionate enquiry; do not end consultation without safety plan if passive ideation confirmed
Prescribing by subtype: AN = no medication (nutritional rehabilitation first); BN = fluoxetine 60mg OD; BED = lisdexamfetamine if moderate-severe (NICE TA607; specialist initiation)
Bone protection (all subtypes from first assessment): calcium + vitamin D; NOT bisphosphonates (teratogenic in reproductive-age women); OCP does NOT protect bone density in AN
3-day GP follow-up call · eating disorder service notified same day · cardiac emergency safety-net communicated · welfare contact confirmed
🚲 2 — MEED Physical Risk Criteria
ParameterEmergency ThresholdClinical Significance
Heart rate<40 bpmBradycardia — cardiac arrest risk
Blood pressure<80/50 mmHgHaemodynamic compromise
Potassium<2.5 mmol/LFatal arrhythmia risk
Blood glucose<3 mmol/LHypoglycaemia
QTc (ECG)>450ms (F) / >430ms (M)Ventricular arrhythmia
Muscle powerUnable to stand from chair without armsSevere proximal myopathy
Rapid weight loss>1 kg/weekTrajectory risk
📋 3 — Subtype Quick Reference
FeatureAnorexia NervosaBulimia NervosaBinge Eating Disorder
Core behaviourRestriction ± purging; compulsive exerciseBinge-purge cycles; compensatory behaviourBinge without compensation
WeightLow — but not always severeUsually normal or aboveOften elevated
AmenorrhoeaCommon (functional hypothalamic)May occurUncommon
First-line RxNutritional rehabilitation; psychological support; NICE eating disorder serviceCBT-ED; guided self-help; fluoxetine 60mg ODCBT-ED; lisdexamfetamine (NICE TA607; specialist)
MedicationNone (NICE); SSRIs ineffective when underweight — QTc riskFluoxetine 60mg OD (NOT 20mg); 3–9 month courseLisdexamfetamine; Schedule 2; specialist initiation
Bone protectionCalcium + VitD; NOT bisphosphonates (teratogenic); OCP does not protect densityStandard fracture risk assessment if amenorrhoeaStandard assessment
⚠ 4 — Key Clinical Rules
NEVER prescribe SSRIs for mood in underweight AN — ineffective + prolongs QTc Fluoxetine for BN = 60mg OD — NOT 20mg (licensed dose) Lisdexamfetamine = specialist initiation only (Schedule 2); NOT in AN or BN Bisphosphonates NOT in reproductive-age women — teratogenic Males: 1 in 4 eating disorder presentations — screen regardless of demographics OCP does NOT protect bone density in AN — calcium + VitD is the intervention Refeeding syndrome: hypophosphataemia + hypokalaemia + hypomagnesaemia — specialist-managed Thiamine BEFORE glucose in malnourished patients (Wernicke’s prevention) Refer to eating disorder service — NOT CMHT; referral does not require confirmed diagnosis Calcium + VitD prescribed from first assessment — not deferred to specialist
🔬 5 — Monitoring and Investigations
InvestigationRationaleTiming
ECG (QTc)Arrhythmia risk; baseline before any medicationFirst assessment; repeat if QTc borderline
U&E + electrolytesPotassium, phosphate, magnesium (purging; refeeding)First assessment; frequency guided by risk
Blood glucoseHypoglycaemia in severe restrictionFirst assessment
FBCAnaemia; leucopenia in ANFirst assessment
LFTsHepatic steatosis in AN; before medicationsFirst assessment
TFTsExclude hypothyroidism (weight loss, amenorrhoea)First assessment
Pregnancy testAmenorrhoea; not all amenorrhoea is functionalFirst assessment (if amenorrhoea)
DEXA scanBone density — refer after 1 year of sustained ANVia eating disorder service
🎓
SCA Exam Quick Reference
Eating Disorders SCA — SCOFF First · MEED · Non-confrontational · No SSRIs in AN
NICE NG69 · Fluoxetine 60mg for BN · Urgent eating disorder service (not CMHT) · Calcium + VitD all
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💬 Opening & ICE
Framing opener (non-diagnostic): “I’m not here to tell you what to eat. I’d like to understand what’s been going on for you — in your own words, what’s brought you in today?”
ICE — Ideas: “What have you made of the changes in your eating and exercise recently? Do you think this is something to be concerned about?”
ICE — Concerns: “What worries you most about what’s happening? Is there anything you’re frightened of finding out today?”
ICE — Expectations: “What would feel like the most helpful thing that could come out of today? Is there anything specific you were hoping I could help with?”
Control function exploration: “You mentioned things have felt uncertain since starting university — what does sticking to your eating and exercise plan give you that feels important?” — this unlocks the control narrative; stay with it if disclosed
Amenorrhoea link: “Did you know that periods can stop when the body isn’t getting enough energy? That’s your body telling us something important.” — often a moment of genuine insight that increases openness
Challenge line: “They’ll just make me gain weight, won’t they?” — “The team’s starting point is listening to you and understanding your life — not imposing things on you. Would you be willing to meet them just once?”
✅ Key SCA Tasks (15pt)
SCOFF ≤5 (1pt): All 5 questions; ≥2/5 = refer without confirmed diagnosis
MEED all criteria (2pt): HR, BP, potassium, glucose, QTc, muscle power, weight trajectory — document each; any emergency criterion = 999 or same-day admission
Eating disorder service referral — urgent (2pt): within 1 week; NOT CMHT; NOT deferred until diagnosis confirmed
ICE all domains integrated (2pt): ideas explored (health narrative); concerns explored (fear of weight gain); expectations (what would help); control function disclosed and acknowledged
Investigations (2pt): ECG (QTc), electrolytes (potassium), glucose, FBC, pregnancy test — all ordered before specialist review
PHQ-9 + suicide risk (2pt): PHQ-9 administered; Q9≥1 = direct compassionate enquiry; safety plan if passive ideation confirmed; do not end consultation without this
Calcium + VitD (1pt): prescribed from first assessment; not deferred; NOT bisphosphonates
SCOFF performed (1pt): structured tool; ≥2/5 = refer
3-day follow-up call (1pt): specific day communicated; concrete commitment
Cardiac safety-net (1pt): “If you develop chest pain, palpitations or feel faint — 999 immediately”
Priya’s welfare role (1pt): discussed with Emma’s consent; framed as support, not surveillance
🔴 Never prescribe SSRIs for mood in underweight AN — ineffective + QTc risk = automatic SCA fail
🔴 Never refer to CMHT — eating disorder service is specialist pathway (NICE NG69)
👥 Relating to Others (11pt)
Non-confrontational illness model (2pt): avoid diagnostic labels early; “you have anorexia” closes Emma down immediately; use body-evidence language: “your body is giving us some signals”
Patient agenda and autonomy (2pt): “I’m not going to tell you what to eat” — immediate reduction in defensiveness; patient-led agenda from outset; “what would feel most helpful today?”
Empathy without reinforcing restriction (2pt): acknowledge the coping function without praising it; “It makes complete sense that when things felt out of control, finding something you could manage felt important”
Safety and suicidality (2pt): PHQ-9 Q9=1 in this case — direct but compassionate: “Sometimes when people are struggling this much, thoughts can come in that things would be simpler if they weren’t there — has anything like that been happening for you?”
Ambivalence as engagement (1pt): “You came today — which tells me part of you wanted to talk about this”; premature reassurance closes conversations; stay curious not prescriptive
Referral framing (1pt): “The team will listen to what your life is like and help you decide what you want”; “Would you be willing to go once?” — realistic achievable outcome is one agreed appointment
Welfare contact (1pt): Priya named as welfare contact with Emma’s explicit agreement; framed as care not supervision: “Would it be OK if I suggested Priya checks in with you over the next few days?”
🟩 Realistic outcome: Emma agrees to eat disorder service “once” — not full acceptance; this is the achievable target; GP should not push for more
💊 Drug Quick-Pick
Reviewed: July 2026 · citations verified against current NICE / UK guidance